A sensitive LC-MS/MS method for simultaneous determination of cabozantinib and its metabolite cabozantinib N -oxide in rat plasma and its application in a pharmacokinetic study

Mutagenic and carcinogenic structural alerts and their mechanisms of action

(2016) Alja Plošnik et al.   Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology

An LC-MS/MS method for rapid and sensitive high-throughput simultaneous determination of various protein kinase inhibitors in human plasma

(2016) Ali S. Abdelhameed et al.   BIOMEDICAL CHROMATOGRAPHY

Clinical Pharmacokinetics of IPX066

(2016) Hsuan-Ming Yao et al.   CLINICAL NEUROPHARMACOLOGY

Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial

(2016) Toni K Choueiri et al.   LANCET ONCOLOGY

An LC-MS/MS method for the quantitation of cabozantinib in rat plasma: Application to a pharmacokinetic study

(2015) Qinghong Su et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Pharmacokinetics and tissue distribution model of cabozantinib in rat determined by UPLC–MS/MS

(2015) Xianqin Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Pharmacokinetic (PK) drug interaction studies of cabozantinib: Effect of CYP3A inducer rifampin and inhibitor ketoconazole on cabozantinib plasma PK and effect of cabozantinib on CYP2C8 probe substrate rosiglitazone plasma PK

(2015) Linh Nguyen et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma

(2015) Toni K. Choueiri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Degradation kinetics study of cabozantinib by a novel stability-indicating LC method and identification of its major degradation products by LC/TOF-MS and LC–MS/MS

(2014) Chunyong Wu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Cabozantinib Inhibits Growth of Androgen-Sensitive and Castration-Resistant Prostate Cancer and Affects Bone Remodeling

(2013) Holly M. Nguyen et al.   PLoS One

Pharmacokinetics, Safety and Tolerability of Bencycloquidium Bromide, a Novel Selective Muscarinic M1/M3 Receptor Antagonist, After Single and Multiple Intranasal Doses in Healthy Chinese Subjects

(2013) Luning Sun et al.   Drugs in research & development

Cabozantinib as a Novel Therapy for Renal Cell Carcinoma

(2013) Ulka Vaishampayan   Current Oncology Reports

Structural analysis and predictive value of the rodent in vivo micronucleus assay results

(2010) R. Benigni et al.   MUTAGENESIS