Article
Virology
Xunyan Ye, Obinna P. Iwuchukwu, Vasanthi Avadhanula, Letisha O. Aideyan, Trevor J. McBride, David M. Henke, Kirtida D. Patel, Felipe-Andres Piedra, Laura S. Angelo, Dimpy P. Shah, Roy F. Chemaly, Pedro A. Piedra
Summary: This study found that specific humoral and mucosal RSV antibodies play an important role in viral clearance in HCT recipients naturally infected with RSV, especially in the clearance of different RSV subtypes. The results of this study have implications for antigen selection in the development of RSV vaccines.
Article
Medicine, General & Internal
Jing Liu, Hai Li, Jie Xia, Xianbo Wang, Yan Huang, Beiling Li, Zhongji Meng, Yanhang Gao, Zhiping Qian, Feng Liu, Xiaobo Lu, Junping Liu, Guohong Deng, Yubao Zheng, Huadong Yan, Liang Qiao, Xiaomei Xiang, Qun Zhang, Ruochan Chen, Jinjun Chen, Sen Luo, La Gao, Liujuan Ji, Jing Li, Xinyi Zhou, Haotang Ren, Sihong Lu, Sumeng Li, Weituo Zhang, Xin Zheng
Summary: This study identified a non-linear association between baseline NLR and the adjusted probability of 90-day transplant-free mortality in cirrhotic patients. The risk of mortality increased with NLR values below 6.5, with patients below 4.5 having the highest risk. The increase in mortality risk with higher NLR was consistent across different subgroups of cirrhotic patients.
FRONTIERS IN MEDICINE
(2021)
Article
Emergency Medicine
Young Joo Seo, Jihion Yu, Jun-Young Park, Narea Lee, Jiwoong Lee, Ji Hyun Park, Hee Yeong Kim, Yu-Gyeong Kong, Young-Kug Kim
Summary: This study evaluated the association between RDW/albumin ratio and 90-day mortality after burn surgery. The results showed that an RDW/albumin ratio greater than 6.8 was associated with higher mortality, prolonged ICU stay rate, and longer ICU stay.
Article
Gastroenterology & Hepatology
Teena Nerwal, Livia Qoshe, Sneha Iyer, Genevieve Medina, Adrian Felix, Harish Lavu, Charles J. Yeo, Jordan M. Winter
Summary: By retrospectively reviewing the vital sign measurements of patients undergoing pancreaticoduodenectomy, it was found that mean systolic blood pressure < 95 mmHg on postoperative day 7 and mean temperature < 96.9 degrees F on postoperative day 3 were high-risk factors for predicting 90-day mortality. These factors can be used to identify patients for closer monitoring in order to rescue patients and prevent death.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Surgery
Manuel Pera, Joan Gibert, Marta Gimeno, Elisenda Garsot, Emma Eizaguirre, Monica Miro, Sandra Castro, Coro Miranda, Lorena Reka, Saioa Leturio, Marta Gonzalez-Duaigues, Clara Codony, Yanina Gobbini, Alexis Luna, Sonia Fernandez-Ananin, Aingeru Sarriugarte, Carles Olona, Joaquin Rodriguez-Santiago, Javier Osorio, Luis Grande
Summary: A risk prediction model for 90-day mortality after gastric cancer surgery was developed and validated using machine learning. The model demonstrated good discrimination capacity in a large cohort of patients. Its use may aid patients and surgeons in making informed decisions.
Article
Surgery
Chami Im, Tak Kyu Oh, In-Ae Song, Young-Tae Jeon
Summary: The study found that preoperative statin use was associated with reduced 90-day mortality and prolonged overall survival for adult patients undergoing elective noncardiac surgery, especially for high-intensity statin users.
Article
Clinical Neurology
Aparna Nutakki, Mashina Chomba, Lorraine Chishimba, Mataa M. Mataa, Stanley Zimba, Michelle Kvalsund, Rebecca F. Gottesman, Mona N. Bahouth, Deanna Saylor
Summary: In a study conducted in Lusaka, hemorrhagic stroke and seizures were identified as independent predictors of in-hospital mortality, while older age and aspiration pneumonia were found to be predictors of 90-day post-discharge mortality.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2022)
Article
Urology & Nephrology
Johan Bjorklund, Par Stattin, Erik Ronmark, Markus Aly, Olof Akre
Summary: This study investigated the cause-specific mortality in the postoperative period after radical prostatectomy (RP) for prostate cancer (PCa). The most common causes of death within 90 days after RP were cardiac disease and venous thromboembolic events. The occurrence of postoperative deaths from metastatic PCa was refuted.
Article
Surgery
Jihion Yu, Yu-Gyeong Kong, Jun -Young Park, Hee Yeong Kim, Miyoung Kwon, Yun Jae Han, Narae Lee, Young Joo Seo, Young-Kug Kim
Summary: High preoperative chart-derived frailty index (CFI) is associated with increased 90-day mortality, major adverse cardiac events, pneumonia, continuous renal replacement therapy requirement, and prolonged ICU stay following burn surgery.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Clinical Neurology
Adrian E. Jimenez, Kyle V. Cicalese, Sachiv Chakravarti, Jose L. Porras, Tej D. Azad, Christopher M. Jackson, Gary L. Gallia, Chetan Bettegowda, Jon Weingart, Debraj Mukherjee
Summary: This study quantified the effects of social determinant of health (SDOH) disparities on postoperative outcomes in brain tumor surgery. The findings indicate that SDOH disparities independently predict a prolonged hospital length of stay and increased 90-day mortality.
JOURNAL OF NEUROSURGERY
(2022)
Article
Education, Scientific Disciplines
Shukaib Arslan, Monzr M. Al Malki
Summary: This article presents a rational and stepwise approach to the use of MMUD for hematopoietic cell transplant in patients with hematologic malignancies. It also reviews novel approaches to reduce the incidence of graft-versus-host disease and improve transplant outcomes in MMUD recipients.
HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM
(2022)
Article
Gastroenterology & Hepatology
Arvid Pourlotfi, Rebecka Ahl Hulme, Gary A. Bass, Gabriel Sjolin, Yang Cao, Peter L. Matthiessen, Shahin Mohseni
Summary: This study retrospectively analyzed data from the Swedish Colorectal Cancer Register to evaluate the association between statin therapy and postoperative mortality following elective colon cancer surgery. The study found that statin users had a significant survival benefit, regardless of age, comorbidity burden, and surgical fitness.
DISEASES OF THE COLON & RECTUM
(2022)
Article
Immunology
Joseph Sassine, Fareed Khawaja, Terri Lynn Shigle, Victoria Handy, Farnaz Foolad, Samuel L. Aitken, Ying Jiang, Richard Champlin, Elizabeth Shpall, Katy Rezvani, Ella J. Ariza-Heredia, Roy F. Chemaly
Summary: Primary prophylaxis with letermovir in CMV-seropositive allogeneic HCT recipients is associated with significant reductions in refractory or resistant CMV infections, nonrelapse mortality at week 48, as well as CS-CMVi and CMV end-organ disease. This approach effectively prevents difficult-to-treat CMV infections and improves outcomes after allogeneic HCT.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Health Care Sciences & Services
Jonathan Handler, Olivia J. J. Lee, Sheena Chatrath, Jeremy McGarvey, Tyler Fitch, Divya Jose, John Vozenilek
Summary: Advance care planning (ACP) is important for end-of-life care, but many people do not engage in it. Timely and accurate mortality prediction can encourage ACP. We evaluated the performance of a new 5-to-90-day mortality predictor across different populations and timeframes and found consistent and equitable results.
JOURNAL OF MEDICAL SYSTEMS
(2023)
Article
Hematology
Warren Fingrut, Arjun Law, Wilson Lam, Fotios V. Michelis, Auro Viswabandya, Jeffrey H. Lipton, Rajat Kumar, Jonas Mattsson, Dennis Dong Hwan Kim
Summary: The study indicates that high levels of ferritin in the blood are associated with poorer outcomes post allogeneic hematopoietic stem cell transplantation (HCT), especially in patients who develop graft-versus-host disease (GVHD). Elevated ferritin(Post-HCT) is linked to lower overall survival and higher non-relapse mortality, indicating its potential as an independent prognostic marker for post-HCT outcomes.
ANNALS OF HEMATOLOGY
(2021)
