Journal
BIOINFORMATICS
Volume 34, Issue 18, Pages 3225-3227Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bty331
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Funding
- Canadian Institutes for Health Research [FDN-154287]
- University of British Columbia 'Four Year Doctoral Fellowship'
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aSummary: Here, we present MetaBridge, a tool that collates protein interactors (curated metabolite-enzyme interactions) that influence the levels of specific metabolites including both biosynthetic and degradative enzymes. This enables network-based integrative analysis of metabolomics data with other omics data types. MetaBridge is designed to complement a systems-biology approach to analysis, pairing well with network analysis tools such as NetworkAnalyst.ca, but can be used in any bioinformatics workflow. Availability and implementation: MetaBridge has been implemented as a web tool at https://www.metabridge.org, and the source code is available at https://github.com/samhinshaw/metabridge_shiny (GNU GPLv3). Contact: bob@hancocklab.com
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