Journal
BIOCHIMIE
Volume 145, Issue -, Pages 2-7Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biochi.2017.11.015
Keywords
Aptamer; Oligonucleotide; Riboswitch; Biosensor; Diagnostic; Pre-clinical and clinical
Categories
Funding
- Novaptech
- Somalogic
- Caris Life Sciences
- Alios Biopharma
- Servier
- Eurogentec
- ChemGenes Corporation
- NanoTemper
- Integrated Dna Technologies
- University of Bordeaux (IdEx Bordeaux, ANR)
- CEA
- Synthetic Biology Bordeaux
- LabEx TRAIL
- SIRIC BRIO
- TecSan
- Bordeaux Metropole
- Region Nouvelle Aquitaine
- 2 Bind
- RNAssist
- Biomedicines
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About 150 participants attended the symposium organised at the Palais de la Bourse in Bordeaux, France on September 22-23, 2017. Thirty speakers from all over the world delivered lectures covering selection processes, aptamer chemistry and innovative applications of these powerful tools that display major advantages over antibodies. Beyond the remarkable science presented, lively discussion and fruitful exchange between participants made this meeting a great success. A series of lectures were focused on synthetic biology (riboswitches, new synthetic base pairs, mutated polymerases). Innovative selection procedures including functional screening of oligonucleotide pools were described. Examples of aptasensors for the detection of pathogens were reported. The potential of aptamers for the diagnostic and the treatment of diseases was also presented. Brief summaries of the lectures presented during the symposium are given in this report. The third edition of this symposium will take place in Boulder, Colorado in Summer 2018 (information available at http://www.aptamers-in-bordeaux.com/). (C) 2017 Elsevier B.V. and Societe Francaise de Biochimie et Biologie Moleculaire (SFBBM). All rights reserved.
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