Journal
BIOCHEMISTRY AND CELL BIOLOGY
Volume 97, Issue 1, Pages 21-29Publisher
CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS
DOI: 10.1139/bcb-2018-0008
Keywords
phagocytosis; target morphology; phagocytic plasticity; phagosomal maturation; phagocytic cup
Categories
Funding
- Natural Sciences and Engineering Research Council of Canada
- Canadian Institutes of Health Research
- Government of Ontario
- Ontario Graduate Scholarship
- Canada Graduate Scholarship
- Ryerson Graduate Fellowship
- Mitacs Postdoctoral Award
Ask authors/readers for more resources
Phagocytosis is an evolutionarily conserved process. In Protozoa, phagocytosis fulfills a feeding mechanism, while in Metazoa, phagocytosis diversified to play multiple organismal roles, including immune defence, tissue homeostasis, and remodeling. Accordingly, phagocytes display a high level of plasticity in their capacity to recognize, engulf, and process targets that differ in composition and morphology. Here, we review how phagocytosis adapts to its multiple roles and discuss in particular the effect of target morphology in phagocytic uptake and phagosome maturation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
