Growth control mechanisms in neuronal regeneration

mTOR coordinates protein synthesis, mitochondrial activity and proliferation

(2015) Masahiro Morita et al.   CELL CYCLE

Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury

(2015) Vera Valakh et al.   NEUROBIOLOGY OF DISEASE

Subtype-Specific Regeneration of Retinal Ganglion Cells following Axotomy: Effects of Osteopontin and mTOR Signaling

(2015) Xin Duan et al.   NEURON

Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

(2015) J. Ruschel et al.   SCIENCE

Enhanced axon outgrowth and improved long-distance axon regeneration in sprouty2 deficient mice

(2014) Letizia Marvaldi et al.   Developmental Neurobiology

Syntaxin13 Expression Is Regulated by Mammalian Target of Rapamycin (mTOR) in Injured Neurons to Promote Axon Regeneration

(2014) Yongcheol Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cAMP-responsive Element-binding Protein (CREB) and cAMP Co-regulate Activator Protein 1 (AP1)-dependent Regeneration-associated Gene Expression and Neurite Growth

(2014) Thong C. Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long-Distance Axonal Growth from Human Induced Pluripotent Stem Cells after Spinal Cord Injury

(2014) Paul Lu et al.   NEURON

Lost in the jungle: new hurdles for optic nerve axon regeneration

(2014) Vincent Pernet et al.   TRENDS IN NEUROSCIENCES

Central Nervous System Regenerative Failure: Role of Oligodendrocytes, Astrocytes, and Microglia

(2014) Jerry Silver et al.   Cold Spring Harbor Perspectives in Biology

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration

(2014) Liu Yang et al.   Nature Communications

PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system

(2014) Radhika Puttagunta et al.   Nature Communications

mTORC1 regulates the efficiency and cellular capacity for protein synthesis

(2013) Christopher G. Proud   BIOCHEMICAL SOCIETY TRANSACTIONS

Injury-Induced HDAC5 Nuclear Export Is Essential for Axon Regeneration

(2013) Yongcheol Cho et al.   CELL

PTEN Inhibition to Facilitate Intrinsic Regenerative Outgrowth of Adult Peripheral Axons

(2013) K. J. Christie et al.   JOURNAL OF NEUROSCIENCE

The Kinesin-2 Family Member KIF3C Regulates Microtubule Dynamics and Is Required for Axon Growth and Regeneration

(2013) L. F. Gumy et al.   JOURNAL OF NEUROSCIENCE

Epigenetic Regulation of Sensory Axon Regeneration after Spinal Cord Injury

(2013) M. J. Finelli et al.   JOURNAL OF NEUROSCIENCE

Axonally Synthesized  -Actin and GAP-43 Proteins Support Distinct Modes of Axonal Growth

(2013) C. J. Donnelly et al.   JOURNAL OF NEUROSCIENCE

Crosstalk between mTOR complexes

(2013) Jianling Xie et al.   NATURE CELL BIOLOGY

Axon–soma communication in neuronal injury

(2013) Ida Rishal et al.   NATURE REVIEWS NEUROSCIENCE

Developmental Decline in Neuronal Regeneration by the Progressive Change of Two Intrinsic Timers

(2013) Y. Zou et al.   SCIENCE

PI3K–GSK3 signalling regulates mammalian axon regeneration by inducing the expression of Smad1

(2013) Saijilafu et al.   Nature Communications

Cross-talk between KLF4 and STAT3 regulates axon regeneration

(2013) Song Qin et al.   Nature Communications

Transcription Factor Oscillations Induce Differential Gene Expressions

(2012) Keng Boon Wee et al.   BIOPHYSICAL JOURNAL

An analytical solution describing the propagation of positive injury signals in an axon: effect of dynein velocity distribution

(2012) A.V. Kuznetsov   COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING

HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration

(2012) Yongcheol Cho et al.   EMBO JOURNAL

Axonal transcription factors signal retrogradely in lesioned peripheral nerve

(2012) Keren Ben-Yaakov et al.   EMBO JOURNAL

Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control

(2012) V. L. Patel et al.   GENES & DEVELOPMENT

Dual Leucine Zipper Kinase Is Required for Retrograde Injury Signaling and Axonal Regeneration

(2012) Jung Eun Shin et al.   NEURON

Subcellular Knockout of Importin β1 Perturbs Axonal Retrograde Signaling

(2012) Rotem Ben-Tov Perry et al.   NEURON

Full-length axon regeneration in the adult mouse optic nerve and partial recovery of simple visual behaviors

(2012) S. de Lima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Motor-Driven Mechanism for Cell-Length Sensing

(2012) Ida Rishal et al.   Cell Reports

Tuning the Orchestra: Transcriptional Pathways Controlling Axon Regeneration

(2012) Andrea Tedeschi   Frontiers in Molecular Neuroscience

Neuronal Intrinsic Mechanisms of Axon Regeneration

(2011) Kai Liu et al.   Annual Review of Neuroscience

The histone acetyltransferase p300 promotes intrinsic axonal regeneration

(2011) Perrine Gaub et al.   BRAIN

Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity

(2011) Christopher J Donnelly et al.   EMBO JOURNAL

Valproic acid improves locomotion in vivo after SCI and axonal growth of neurons in vitro

(2011) Lei Lv et al.   EXPERIMENTAL NEUROLOGY

Axonal Localization of Transgene mRNA in Mature PNS and CNS Neurons

(2011) D. E. Willis et al.   JOURNAL OF NEUROSCIENCE

Netrin-1-Induced Local  -Actin Synthesis and Growth Cone Guidance Requires Zipcode Binding Protein 1

(2011) K. Welshhans et al.   JOURNAL OF NEUROSCIENCE

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

(2011) Fang Sun et al.   NATURE

Axon Regeneration Pathways Identified by Systematic Genetic Screening in C. elegans

(2011) Lizhen Chen et al.   NEURON

In vivo imaging reveals a phase-specific role of STAT3 during central and peripheral nervous system axon regeneration

(2011) F. M. Bareyre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation

(2010) P Gaub et al.   CELL DEATH AND DIFFERENTIATION

Mammalian Target of Rapamycin (mTOR) Activation Increases Axonal Growth Capacity of Injured Peripheral Nerves

(2010) Namiko Abe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Roles of c-Jun N-Terminal Kinase Isoforms in Neurite Initiation and Elongation during Axonal Regeneration

(2010) M. Barnat et al.   JOURNAL OF NEUROSCIENCE

Long-Distance Axon Regeneration in the Mature Optic Nerve: Contributions of Oncomodulin, cAMP, and pten Gene Deletion

(2010) T. Kurimoto et al.   JOURNAL OF NEUROSCIENCE

Calcium and Cyclic AMP Promote Axonal Regeneration in Caenorhabditis elegans and Require DLK-1 Kinase

(2010) A. Ghosh-Roy et al.   JOURNAL OF NEUROSCIENCE

Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-κB dependent AP-1-mediated ICAM-1 expression in breast cancer cells

(2010) Mansoor Ahmed et al.   Molecular Cancer

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization

(2010) L. F. Gumy et al.   RNA

Local calcium-dependent mechanisms determine whether a cut axonal end assembles a retarded endbulb or competent growth cone

(2009) Dotan Kamber et al.   EXPERIMENTAL NEUROLOGY

A conditioning lesion induces changes in gene expression and axonal transport that enhance regeneration by increasing the intrinsic growth state of axons

(2009) Paul N. Hoffman   EXPERIMENTAL NEUROLOGY

Sunday Driver Interacts with Two Distinct Classes of Axonal Organelles

(2009) Namiko Abe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Synthesis of Spermidine as a Result of Upregulation of Arginase I Promotes Axonal Regeneration in Culture and In Vivo

(2009) K. Deng et al.   JOURNAL OF NEUROSCIENCE

MyosinV controls PTEN function and neuronal cell size

(2009) Michiel T. van Diepen et al.   NATURE CELL BIOLOGY

SOCS3 Deletion Promotes Optic Nerve Regeneration In Vivo

(2009) Patrice D. Smith et al.   NEURON

HDAC6 is a target for protection and regeneration following injury in the nervous system

(2009) M. A. Rivieccio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Can Molecular Motors Drive Distance Measurements in Injured Neurons?

(2009) Naaman Kam et al.   PLoS Computational Biology

Sox11 transcription factor modulates peripheral nerve regeneration in adult mice

(2008) Michael P. Jankowski et al.   BRAIN RESEARCH

A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth and regeneration

(2008) A Tedeschi et al.   CELL DEATH AND DIFFERENTIATION

Signaling cascades as cellular devices for spatial computations

(2008) Jörg Stelling et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Frequency-modulated nuclear localization bursts coordinate gene regulation

(2008) Long Cai et al.   NATURE

Localized Regulation of Axonal RanGTPase Controls Retrograde Injury Signaling in Peripheral Nerve

(2008) Dmitry Yudin et al.   NEURON

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

(2008) K. K. Park et al.   SCIENCE