A sweet code for glycoprotein folding

Crystal Structure and Functional Analyses of the Lectin Domain of Glucosidase II: Insights into Oligomannose Recognition

(2015) Linda J. Olson et al.   BIOCHEMISTRY

Glucosidase II and MRH-Domain Containing Proteins in the Secretory Pathway

(2015) Cecilia D’Alessio et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Calreticulin and Arginylated Calreticulin Have Different Susceptibilities to Proteasomal Degradation

(2015) Victor E. Goitea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reglucosylation by UDP-glucose:glycoprotein glucosyltransferase 1 delays glycoprotein secretion but not degradation

(2015) Abla Tannous et al.   MOLECULAR BIOLOGY OF THE CELL

Mammalian ER mannosidase I resides in quality control vesicles, where it encounters its glycoprotein substrates

(2015) Ron Benyair et al.   MOLECULAR BIOLOGY OF THE CELL

Both isoforms of human UDP-glucose:glycoprotein glucosyltransferase are enzymatically active

(2014) Yoichi Takeda et al.   GLYCOBIOLOGY

Trimming of glucosylated N-glycans by human ER α1,2-mannosidase I

(2014) Jun-ichi Aikawa et al.   JOURNAL OF BIOCHEMISTRY

ER-associated degradation: Protein quality control and beyond

(2014) Annamaria Ruggiano et al.   JOURNAL OF CELL BIOLOGY

Structural insight into substrate recognition by the endoplasmic reticulum folding-sensor enzyme: crystal structure of third thioredoxin-like domain of UDP-glucose:glycoprotein glucosyltransferase

(2014) Tong Zhu et al.   Scientific Reports

Antiviral therapies targeting host ER alpha-glucosidases: Current status and future directions

(2013) Jinhong Chang et al.   ANTIVIRAL RESEARCH

Diverse Effects of Macromolecular Crowding on the Sequential Glycan-Processing Pathway Involved in Glycoprotein Quality Control

(2013) Hikaru Matsushima et al.   CHEMBIOCHEM

Endoplasmic reticulum lectin XTP3-B inhibits endoplasmic reticulum-associated degradation of a misfolded α1-antitrypsin variant

(2013) Tsutomu Fujimori et al.   FEBS Journal

Glycan-dependent and -independent Interactions Contribute to Cellular Substrate Recruitment by Calreticulin

(2013) Sanjeeva J. Wijeyesakere et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitoylation is the switch that assigns calnexin to quality control or ER Ca2+ signaling

(2013) E. M. Lynes et al.   JOURNAL OF CELL SCIENCE

UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum

(2013) Sean P. Ferris et al.   MOLECULAR BIOLOGY OF THE CELL

The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation

(2013) Jeffrey M. Williams et al.   MOLECULAR BIOLOGY OF THE CELL

Calnexin Controls the STAT3-Mediated Transcriptional Response to EGF

(2013) Asvin K.K. Lakkaraju et al.   MOLECULAR CELL

Redox-Dependent Protein Quality Control in the Endoplasmic Reticulum: Folding to Degradation

(2012) Masatoshi Hagiwara et al.   ANTIOXIDANTS & REDOX SIGNALING

Chemical Synthesis of Intentionally Misfolded Homogeneous Glycoprotein: A Unique Approach for the Study of Glycoprotein Quality Control

(2012) Masayuki Izumi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Calreticulin in the immune system: ins and outs

(2012) Malini Raghavan et al.   TRENDS IN IMMUNOLOGY

The Expanding Horizons of Asparagine-Linked Glycosylation

(2011) Angelyn Larkin et al.   BIOCHEMISTRY

GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum

(2011) Michal Marzec et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Roles of the 15-kDa Selenoprotein (Sep15) in Redox Homeostasis and Cataract Development Revealed by the Analysis of Sep 15 Knockout Mice

(2011) Marina V. Kasaikina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Early EDEM1 Protein Maturation Events and Their Functional Implications

(2011) Taku Tamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of cysteine amino acid residues in calnexin

(2011) Helen Coe et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Glucosidase II and N-glycan mannose content regulate the half-lives of monoglucosylated species in vivo

(2011) Ivan D. Stigliano et al.   MOLECULAR BIOLOGY OF THE CELL

X-Ray Structure of the Human Calreticulin Globular Domain Reveals a Peptide-Binding Area and Suggests a Multi-Molecular Mechanism

(2011) Anne Chouquet et al.   PLoS One

The Two Caenorhabditis elegans UDP-Glucose:Glycoprotein Glucosyltransferase Homologues Have Distinct Biological Functions

(2011) Lucila I. Buzzi et al.   PLoS One

Essential glycan-dependent interactions optimize MHC class I peptide loading

(2011) P. A. Wearsch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein translocation across the ER membrane

(2010) Richard Zimmermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Precision Mapping of an In Vivo N-Glycoproteome Reveals Rigid Topological and Sequence Constraints

(2010) Dorota F. Zielinska et al.   CELL

EDEM1 accelerates the trimming of  1,2-linked mannose on the C branch of N-glycans

(2010) N. Hosokawa et al.   GLYCOBIOLOGY

Calnexin Deficiency Leads to Dysmyelination

(2010) Allison Kraus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calreticulin Is a Thermostable Protein with Distinct Structural Responses to Different Divalent Cation Environments

(2010) Sanjeeva J. Wijeyesakere et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain

(2010) Guennadi Kozlov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mannose Trimming Is Required for Delivery of a Glycoprotein from EDEM1 to XTP3-B and to Late Endoplasmic Reticulum-associated Degradation Steps

(2010) Bella Groisman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin

(2010) Bradley R. Pearse et al.   JOURNAL OF CELL BIOLOGY

Organization of the Sec61 Translocon, Studied by High Resolution Native Electrophoresis

(2010) Kurt Dejgaard et al.   JOURNAL OF PROTEOME RESEARCH

Functional cooperation between BiP and calreticulin in the folding maturation of a glycoprotein in Trypanosoma cruzi

(2010) Carlos A. Labriola et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Endoplasmic Reticulum Calcium Regulates the Retrotranslocation of Trypanosoma Cruzi Calreticulin to the Cytosol

(2010) Carlos A. Labriola et al.   PLoS One

Sep15, a Thioredoxin-like Selenoprotein, Is Involved in the Unfolded Protein Response and Differentially Regulated by Adaptive and Acute ER Stresses

(2009) Vyacheslav M. Labunskyy et al.   BIOCHEMISTRY

The Recognition Motif of the Glycoprotein-Folding Sensor Enzyme UDP-Glc:Glycoprotein Glucosyltransferase†

(2009) Kiichiro Totani et al.   BIOCHEMISTRY

Calreticulin: non-endoplasmic reticulum functions in physiology and disease

(2009) Leslie I. Gold et al.   FASEB JOURNAL

Human XTP3-B binds to  1-antitrypsin variant nullHong Kong via the C-terminal MRH domain in a glycan-dependent manner

(2009) D. Yamaguchi et al.   GLYCOBIOLOGY

Genetic analysis of glucosidase II β-subunit in trimming of high-mannose-type glycans

(2009) Taisuke Watanabe et al.   GLYCOBIOLOGY

Sugar-binding activity of the MRH domain in the ER  -glucosidase II   subunit is important for efficient glucose trimming

(2009) D. Hu et al.   GLYCOBIOLOGY

The sugar-binding ability of human OS-9 and its involvement in ER-associated degradation

(2009) Kaoru Mikami et al.   GLYCOBIOLOGY

The Structure of Calreticulin C-terminal Domain Is Modulated by Physiological Variations of Calcium Concentration

(2009) Ana María Villamil Giraldo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human OS-9, a Lectin Required for Glycoprotein Endoplasmic Reticulum-associated Degradation, Recognizes Mannose-trimmedN-Glycans

(2009) Nobuko Hosokawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucosidase II β Subunit Modulates N-Glycan Trimming in Fission Yeasts and Mammals

(2009) Ivan D. Stigliano et al.   MOLECULAR BIOLOGY OF THE CELL

Darwinian selection for sites of Asn-linked glycosylation in phylogenetically disparate eukaryotes and viruses

(2009) J. Cui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential phosphorylation of calreticulin affects AT1 receptor mRNA stability in VSMC

(2008) Cornelius F.H. Mueller et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endoplasmic Reticulum Glucosidase II Is Inhibited by Its End Products

(2008) Eran Bosis et al.   BIOCHEMISTRY

Thyroid Hormone Receptor α1 Follows a Cooperative CRM1/Calreticulin-mediated Nuclear Export Pathway

(2008) Matthew E. Grespin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate Specificity of the Oxidoreductase ERp57 Is Determined Primarily by Its Interaction with Calnexin and Calreticulin

(2008) Catherine E. Jessop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cotranslational Maturation Program for the Type II Membrane GlycoproteinInfluenzaNeuraminidase

(2008) Ning Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Macromolecular Crowding on Glycoprotein Processing Enzymes

(2008) Kiichiro Totani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER

(2008) R. Ushioda et al.   SCIENCE

Endoplasmic Reticulum (ER) Mannosidase I Is Compartmentalized and Required for N-Glycan Trimming to Man5–6GlcNAc2 in Glycoprotein ER-associated Degradation

(2007) Edward Avezov et al.   MOLECULAR BIOLOGY OF THE CELL