Journal
BEHAVIOURAL PROCESSES
Volume 157, Issue -, Pages 601-609Publisher
ELSEVIER
DOI: 10.1016/j.beproc.2018.04.010
Keywords
Social defeat; Contextual conditioning; Contextual memory; Self-grooming
Categories
Funding
- Sao Paulo Research Foundation (FAPESP) [2013/01383-6]
- National Council for Scientific and Technological Development (CNPq) [478696/2013-2]
- PADC/FCF-UNESP
- CNPq [131661/2013-2]
- FAPESP [2011/04561-1]
- CNPq fellowship [306556/2015-4]
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Aggressive interactions between conspecific animals have been used as a social stressor with ethological characteristics to study how social interactions can modulate animal's behavior. Here, a new protocol based on aggressive and non-aggressive interactions was developed to study how different social interactions can alter the behavioral profile of animals re-exposed to the context in which the interaction occurred. We used factor analysis to trace the behavioral profile of socially defeated and non-defeated mice when they were re-exposed to the apparatus [three interconnected chambers: home chamber, tunnel and surface area]; we also compared the behavior presented before (habituation) and 24 h after (re-exposure) the non-aggressive or aggressive interactions. A final factor analysis from defeated animals yielded 4 factors that represented 72.09% of total variance; whereas non-defeated animal's analysis was loaded with 5 factors that represented 85.46% of total variance. A 5-min non-aggressive interaction reduced the frequency of stretched attend behavior in the tunnel, whereas a single social defeat reduced time in the tunnel and increased time spent performing self-grooming in the home chamber without conditioning any other spatio-temporal and complementary measures. Together, these results suggest that different social interactions may modulate distinct behavioral profiles in animals when re-exposed to the context.
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