Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes

The Curvature Sensitivity of a Membrane-Binding Amphipathic Helix Can Be Modulated by the Charge on a Flanking Region

(2014) Sharon S. Y. Chong et al.   BIOCHEMISTRY

Conformational heterogeneity of α -synuclein in membrane

(2014) Josh V. Vermaas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

GRP78 clustering at the cell surface of neurons transduces the action of exogenous alpha-synuclein

(2014) S Bellani et al.   CELL DEATH AND DIFFERENTIATION

Introducing Protein Intrinsic Disorder

(2014) Johnny Habchi et al.   CHEMICAL REVIEWS

α-Synuclein oligomers distinctively permeabilize complex model membranes

(2014) Anja N. D. Stefanovic et al.   FEBS Journal

Sequence and Membrane Determinants of the Random Coil–Helix Transition of α-Synuclein

(2014) Sowmya B. Lokappa et al.   JOURNAL OF MOLECULAR BIOLOGY

Lysine residues at the first and second KTKEGV repeats mediate α-Synuclein binding to membrane phospholipids

(2014) Yonaton Zarbiv et al.   NEUROBIOLOGY OF DISEASE

N-Alpha-Acetylation of α-Synuclein Increases Its Helical Folding Propensity, GM1 Binding Specificity and Resistance to Aggregation

(2014) Tim Bartels et al.   PLoS One

Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour

(2014) Giuliana Fusco et al.   Nature Communications

One single method to produce native and Tat-fused recombinant human α-synuclein in Escherichia coli

(2013) Laura Caldinelli et al.   BMC BIOTECHNOLOGY

Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates

(2013) Donatella Diana et al.   CHEMISTRY-A EUROPEAN JOURNAL

Exploring the accessible conformations of N-terminal acetylated α-synuclein

(2013) Gina M. Moriarty et al.   FEBS LETTERS

In VivoCross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural Cells

(2013) Ulf Dettmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In-Cell NMR Characterization of the Secondary Structure Populations of a Disordered Conformation of α-Synuclein within E. coli Cells

(2013) Christopher A. Waudby et al.   PLoS One

The remarkable conformational plasticity of alpha-synuclein: blessing or curse?

(2013) Angélique Deleersnijder et al.   TRENDS IN MOLECULAR MEDICINE

Bacterial in-cell NMR of human α-synuclein: a disordered monomer by nature?: Figure 1

(2012) Andres Binolfi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Heterotypic Sam-Sam Association between Odin-Sam1 and Arap3-Sam: Binding Affinity and Structural Insights

(2012) Flavia A. Mercurio et al.   CHEMBIOCHEM

α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, andEscherichia coliExists Predominantly as Disordered Monomer

(2012) Bruno Fauvet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

(2011) Tim Bartels et al.   NATURE

A soluble  -synuclein construct forms a dynamic tetramer

(2011) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

(2010) He-Jin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biophysics of Parkinsons Disease: Structure and Aggregation of α- Synuclein

(2009) Vladimir Uversky et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Multiple Tight Phospholipid-Binding Modes of α-Synuclein Revealed by Solution NMR Spectroscopy

(2009) Christina R. Bodner et al.   JOURNAL OF MOLECULAR BIOLOGY

Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions

(2007) Peter Tompa et al.   TRENDS IN BIOCHEMICAL SCIENCES