E3 ubiquitin ligase Cbl-b suppresses human ORMDL3 expression through STAT6 mediation

E3 Ubiquitin Ligase Cbl-b Regulates Thymic-Derived CD4+CD25+Regulatory T Cell Development by Targeting Foxp3 for Ubiquitination

(2015) Yixia Zhao et al.   JOURNAL OF IMMUNOLOGY

E3 Ubiquitin Ligase Cbl-b Suppresses Proallergic T Cell Development and Allergic Airway Inflammation

(2014) Guilin Qiao et al.   Cell Reports

Signal transducer and activator of transcription 6 directly regulates human ORMDL3 expression

(2013) Rongfang Qiu et al.   FEBS Journal

T Cell Activation Threshold Regulated by E3 Ubiquitin Ligase Cbl-b Determines Fate of Inducible Regulatory T Cells

(2013) G. Qiao et al.   JOURNAL OF IMMUNOLOGY

Promoter Characterization and Role of cAMP/PKA/CREB in the Basal Transcription of the Mouse ORMDL3 Gene

(2013) Li-Li Zhuang et al.   PLoS One

All-Trans Retinoic Acid Modulates ORMDL3 Expression via Transcriptional Regulation

(2013) Li-Li Zhuang et al.   PLoS One

Peptide-induced immune regulation by a promiscuous and immunodominant CD4T-cell epitope of Timothy grass pollen: a role of Cbl-b and Itch in regulation

(2013) Stephen J Till et al.   THORAX

ORMDL3 modulates store-operated calcium entry and lymphocyte activation

(2012) Amado Carreras-Sureda et al.   HUMAN MOLECULAR GENETICS

Mechanisms elevating ORMDL3 expression in recurrent wheeze patients: Role of Ets-1, p300 and CREB

(2012) Rui Jin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

STAT6 expression in T cells, alveolar macrophages and bronchial biopsies of normal and asthmatic subjects

(2012) Katsuyuki Tomita et al.   Journal of Inflammation-London

Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma

(2012) V Berce et al.   PHARMACOGENOMICS JOURNAL

ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6

(2012) M. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide association study to identify genetic determinants of severe asthma

(2012) Y I Wan et al.   THORAX

Characterization of a novel isoform of the human ORMDL3 gene

(2011) Rui Jin et al.   CELL AND TISSUE RESEARCH

Rhinovirus bronchiolitis and recurrent wheezing: 1-year follow-up

(2011) F. Midulla et al.   EUROPEAN RESPIRATORY JOURNAL

Effects of a 17q21 chromosome gene variant, tobacco smoke and furred pets on infant wheeze

(2011) E V Bräuner et al.   GENES AND IMMUNITY

Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL-17 secretion

(2011) Anna Lluis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice

(2011) Charles Perkins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STAT6-Dependent Regulation of Th9 Development

(2011) R. Goswami et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association study of bronchial asthma in the Volga-Urals region of Russia

(2011) A. S. Karunas et al.   MOLECULAR BIOLOGY

Cbl-b regulates airway mucosal tolerance to aeroallergen

(2010) S. Y. Oh et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Genome-wide Profiling of Interleukin-4 and STAT6 Transcription Factor Regulation of Human Th2 Cell Programming

(2010) Laura L. Elo et al.   IMMUNITY

Allele-Specific Chromatin Remodeling in the ZPBP2/GSDMB/ORMDL3 Locus Associated with the Risk of Asthma and Autoimmune Disease

(2009) Dominique J. Verlaan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress

(2009) Gerard Cantero-Recasens et al.   HUMAN MOLECULAR GENETICS