AMPK inhibits MTDH expression via GSK3β and SIRT1 activation: potential role in triple negative breast cancer cell proliferation

Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase

(2015) Carlos T. Pineda et al.   CELL

Targeting Mutant p53 by a SIRT1 Activator YK-3-237 Inhibits the Proliferation of Triple-Negative Breast Cancer Cells

(2015) Yong Weon Yi et al.   Oncotarget

Knockdown of astrocyte elevated gene-1 inhibits tumor growth and modifies microRNAs expression profiles in human colorectal cancer cells

(2014) Sujun Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AMPK Reverses the Mesenchymal Phenotype of Cancer Cells by Targeting the Akt–MDM2–Foxo3a Signaling Axis

(2014) Chih-Chien Chou et al.   CANCER RESEARCH

Statin-induced inhibition of breast cancer proliferation and invasion involves attenuation of iron transport: intermediacy of nitric oxide and antioxidant defence mechanisms

(2014) Anantha Koteswararao Kanugula et al.   FEBS Journal

Antitumor Effects of a Sirtuin Inhibitor, Tenovin-6, against Gastric Cancer Cells via Death Receptor 5 Up-Regulation

(2014) Sachiko Hirai et al.   PLoS One

Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy

(2013) Joungmok Kim et al.   CELL

Establishment and Characterization of MTDH Knockdown by Artificial Micro RNA Interference - Functions as a Potential Tumor Suppressor in Breast Cancer

(2012) Song Wang et al.   Asian Pacific Journal of Cancer Prevention

Anticancer Properties of Pomolic Acid-Induced AMP-Activated Protein Kinase Activation in MCF7 Human Breast Cancer Cells

(2012) Seog Hyeon Youn et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Role of Nuclear Factor-ĸB in Breast and Colorectal Cancer

(2012) Adeel Zubair et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Cancer Cell Survival Following DNA Damage-mediated Premature Senescence Is Regulated by Mammalian Target of Rapamycin (mTOR)-dependent Inhibition of Sirtuin 1

(2011) Jung Ho Back et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Knockdown of MTDH Sensitizes Endometrial Cancer Cells to Cell Death Induction by Death Receptor Ligand TRAIL and HDAC Inhibitor LBH589 Co-Treatment

(2011) Xiangbing Meng et al.   PLoS One

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Astrocyte elevated gene-1 induces protective autophagy

(2010) S. K. Bhutia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Multifaceted Role of MTDH/AEG-1 in Cancer Progression

(2009) G. Hu et al.   CLINICAL CANCER RESEARCH

Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression

(2009) Byoung Kwon Yoo et al.   JOURNAL OF CLINICAL INVESTIGATION

Knockdown of astrocyte elevated gene-1 inhibits proliferation and enhancing chemo-sensitivity to cisplatin or doxorubicin in neuroblastoma cells

(2009) Haiyan Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

AMP-activated protein kinase promotes human prostate cancer cell growth and survival

(2009) H. U. Park et al.   MOLECULAR CANCER THERAPEUTICS

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Somatic LKB1 Mutations Promote Cervical Cancer Progression

(2009) Shana N. Wingo et al.   PLoS One

Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis

(2009) Luni Emdad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Basis of Nuclear Factor- B Activation by Astrocyte Elevated Gene-1

(2008) D. Sarkar et al.   CANCER RESEARCH

Astrocyte Elevated Gene-1 is a Novel Prognostic Marker for Breast Cancer Progression and Overall Patient Survival

(2008) J. Li et al.   CLINICAL CANCER RESEARCH

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL