EGFR and IGF-1R in regulation of prostate cancer cell phenotype and polarity: opposing functions and modulation by T-cadherin

Cross-talk between EGFR and T-cadherin: EGFR activation promotes T-cadherin localization to intercellular contacts

(2013) Emmanouil Kyriakakis et al.   CELLULAR SIGNALLING

T-cadherin loss promotes experimental metastasis of squamous cell carcinoma

(2013) Maria Philippova et al.   EUROPEAN JOURNAL OF CANCER

T-cadherin Is Essential for Adiponectin-mediated Revascularization

(2013) Jennifer L. Parker-Duffen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches

(2013) T Karantanos et al.   ONCOGENE

N-Cadherin Dependent Collective Cell Invasion of Prostate Cancer Cells Is Regulated by the N-Terminus of α-Catenin

(2013) Yuanyuan Cui et al.   PLoS One

T-cadherin attenuates insulin-dependent signalling, eNOS activation, and angiogenesis in vascular endothelial cells

(2012) Maria Philippova et al.   CARDIOVASCULAR RESEARCH

Diverse Functions of IGF/Insulin Signaling in Malignant and Noncancerous Prostate Cells: Proliferation in Cancer Cells and Differentiation in Noncancerous Cells

(2012) Isabel Heidegger et al.   ENDOCRINOLOGY

T-Cadherin Is an Auxiliary Negative Regulator of EGFR Pathway Activity in Cutaneous Squamous Cell Carcinoma: Impact on Cell Motility

(2012) Emmanouil Kyriakakis et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Expression of the IGF Axis Is Decreased in Local Prostate Cancer but Enhanced after Benign Prostate Epithelial Differentiation and TGF-β Treatment

(2011) Petra Massoner et al.   AMERICAN JOURNAL OF PATHOLOGY

Castration-Resistant Prostate Cancer: Targeted Therapies

(2011) S. Leo et al.   CHEMOTHERAPY

Paradoxical effects of T-cadherin on squamous cell carcinoma: up- and down-regulation increase xenograft growth by distinct mechanisms

(2011) Dennis Pfaff et al.   JOURNAL OF PATHOLOGY

Plasma and tissue insulin-like growth factor-I receptor (IGF-IR) as a prognostic marker for prostate cancer and anti-IGF-IR agents as novel therapeutic strategy for refractory cases: A review

(2011) Emine Elif Ozkan   MOLECULAR AND CELLULAR ENDOCRINOLOGY

T-cadherin loss induces an invasive phenotype in human keratinocytes and squamous cell carcinoma (SCC) cells in vitro and is associated with malignant transformation of cutaneous SCC in vivo

(2010) D. Pfaff et al.   BRITISH JOURNAL OF DERMATOLOGY

Targeted therapeutic approaches for hormone-refractory prostate cancer

(2010) Flora Stavridi et al.   CANCER TREATMENT REVIEWS

Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene

(2010) Hagit Schayek et al.   EXPERIMENTAL CELL RESEARCH

Epidermal growth factor receptor expression escapes androgen regulation in prostate cancer: a potential molecular switch for tumour growth

(2009) A M Traish et al.   BRITISH JOURNAL OF CANCER

A guide and guard: The many faces of T-cadherin

(2009) Maria Philippova et al.   CELLULAR SIGNALLING

Conditional Deletion of Insulin-like Growth Factor-I Receptor in Prostate Epithelium

(2008) B. W. Sutherland et al.   CANCER RESEARCH

T-cadherin Supports Angiogenesis and Adiponectin Association with the Vasculature in a Mouse Mammary Tumor Model

(2008) L. W. Hebbard et al.   CANCER RESEARCH

Cadherins in development and cancer

(2008) Marc P. Stemmler   Molecular BioSystems

Cadherin-11 Promotes the Metastasis of Prostate Cancer Cells to Bone

(2008) K. Chu et al.   MOLECULAR CANCER RESEARCH

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY