Characterization of the Preclinical Pharmacology of the New 2-Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention

Rapid decline in the susceptibility of Plasmodium falciparum to dihydroartemisinin–piperaquine in the south of Vietnam

(2017) Ngo Viet Thanh et al.   MALARIA JOURNAL

Lead Selection of a New Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention

(2016) Marina Chavchich et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Declining Efficacy of Artemisinin Combination Therapy AgainstP. FalciparumMalaria on the Thai–Myanmar Border (2003–2013): The Role of Parasite Genetic Factors

(2016) Aung Pyae Phyo et al.   CLINICAL INFECTIOUS DISEASES

Primaquine pharmacology in the context of CYP 2D6 pharmacogenomics: Current state of the art

(2016) Sean R. Marcsisin et al.   PHARMACOLOGY & THERAPEUTICS

Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study

(2015) Michele D Spring et al.   LANCET INFECTIOUS DISEASES

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

(2015) S. Bhatt et al.   NATURE

Pharmacokinetic Interactions between Primaquine and Pyronaridine-Artesunate in Healthy Adult Thai Subjects

(2014) Podjanee Jittamala et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

JPC-2997, a New Aminomethylphenol with HighIn VitroandIn VivoAntimalarial Activities against Blood Stages of Plasmodium

(2014) Geoffrey W. Birrell et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dihydroartemisinin–Piperaquine Failure in Cambodia

(2014) David L. Saunders et al.   NEW ENGLAND JOURNAL OF MEDICINE

Designing the next generation of medicines for malaria control and eradication

(2013) Jeremy N Burrows et al.   MALARIA JOURNAL

Review of pyronaridine anti-malarial properties and product characteristics

(2012) Simon L Croft et al.   MALARIA JOURNAL

Compilation of 222 drugs’ plasma protein binding data and guidance for study designs

(2011) Fengling Zhang et al.   DRUG DISCOVERY TODAY

Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice

(2011) Geoffrey S Dow et al.   MALARIA JOURNAL

Addressing Central Nervous System (CNS) Penetration in Drug Discovery: Basics and Implications of the Evolving New Concept

(2009) Andreas Reichel   CHEMISTRY & BIODIVERSITY

Candidate Selection and Preclinical Evaluation ofN-tert-Butyl Isoquine (GSK369796), An Affordable and Effective 4-Aminoquinoline Antimalarial for the 21st Century

(2009) Paul M. O’Neill et al.   JOURNAL OF MEDICINAL CHEMISTRY

Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia

(2009) William O Rogers et al.   MALARIA JOURNAL

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE