Journal
EXPERT REVIEW OF NEUROTHERAPEUTICS
Volume 15, Issue 6, Pages 621-628Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1586/14737175.2015.1044982
Keywords
doose syndrome; epilepsy; GLUT-1 deficiency; infantile spasms; ketogenic; lennox-gastaut syndrome; low glycemic index diet; MCT diet; modified atkins diet; seizures
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Available pharmacologic treatments for seizures are limited in their efficacy. For a patient with seizures, pharmacologic treatment with available anticonvulsant medications leads to seizure control in <70% of patients. Surgical resection can lead to control in a select subset of patients but still leaves a significant number of patients with uncontrolled seizures. The ketogenic diet and related diets have proven to be useful in pharmacoresistant childhood epilepsy.
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