Article
Oncology
E. M. B. P. Reuling, D. D. Naves, K. J. Hartemink, E. H. F. M. van der Heijden, P. W. Plaisier, A. F. T. M. Verhagen, J. M. A. Daniels, C. Dickhoff
Summary: This study evaluated the impact of endobronchial therapy (EBT) on bronchial carcinoid, and whether EBT reduces the extent of surgical resection or increases surgical morbidity. The analysis found no significant difference in postoperative complications between patients who underwent EBT before surgery and those who did not.
Article
Oncology
Hao Yang, Tong Liu, Mengqi Li, Zhanglan Fang, Ling Luo
Summary: This study aimed to evaluate the prognostic impact of the number of examined lymph nodes (ELNs) on the long-term survival of patients with early-stage pulmonary typical carcinoid tumors (TC). The results showed that a higher number of ELNs was associated with a greater long-term survival rate. Therefore, the authors recommend using at least 4 ELNs as the cutoff value for evaluating the prognosis of early-stage TCs, especially for patients with a tumor size of 1.1 to 3.0 cm.
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
(2022)
Article
Surgery
Julie Hallet, Calvin Law
Summary: The management of nodal disease in SB-NETs remains controversial, with debates on the extent of lymph node dissection for localized tumors. While resection is important, it should be balanced with functional outcomes. Nodal dissection is useful for staging in localized disease, but the benefit in survival remains unclear. Different stages of nodal extent should be considered in loco-regional disease to guide appropriate resection strategies.
WORLD JOURNAL OF SURGERY
(2021)
Article
Surgery
Yuki Fujii, Ching-Wei Tzeng, Yi-Ju Chiang, Daniel M. Halperin, Arvind Dasari, Michael P. Kim, Matthew H. G. Katz, Jeffrey E. Lee, Naruhiko Ikoma
Summary: The study found that the presence of regional LN metastases and the extent of surgery did not affect overall survival among patients with D-NETs. Radical resection to clear occult LN metastases for nonfunctioning, sporadic D-NETs was not supported by the current study.
JOURNAL OF SURGICAL RESEARCH
(2021)
Article
Oncology
Yeong Jeong Jeon, Junghee Lee, Sumin Shin, Jong Ho Cho, Yong Soo Choi, Jhingook Kim, Jae Ill Zo, Young Mog Shim, Yoon-La Choi, Hong Kwan Kim
Summary: This study aimed to evaluate the impact of micropapillary and/or solid components on survival and recurrence of patients with resected stage I lung adenocarcinoma (LUAD). The results showed that complete lymph node assessment had a favorable prognostic effect on overall survival and recurrence-free survival in MPSOL(+) patients. A complete lymph node assessment would be required, even if sublobar resection is unavoidable, for patients with solid tumor or tumor>2 cm.
Article
Surgery
Song Xu, Xiongfei Li, Fan Ren, Jinling He, Shikang Zhao, Yanye Wang, Dian Ren, Shuai Zhu, Xi Lei, Gang Chen, Jun Chen
Summary: This study aimed to determine the optimal surgical procedure for early-stage pulmonary carcinoids (PCs). Through a retrospective study and propensity score matching analysis, it was found that sublobar resection may not significantly compromise the long-term oncological outcomes in early-stage PCs with a diameter <= 3 cm if lymph node assessment is performed adequately.
Article
Oncology
Yukiharu Hiyoshi, Nobuya Daitoku, Toshiki Mukai, Toshiya Nagasaki, Tomohiro Yamaguchi, Takashi Akiyoshi, Chihiro Yasue, Akiko Chino, Shoichi Saito, Manabu Takamatsu, Yosuke Fukunaga
Summary: This study analyzed the risk factors and prognostic impact of lymph node (LN) metastasis in 195 patients with stage I-III rectal neuroendocrine tumors (NETs) who underwent radical surgery. The study found that tumor size > 10 mm, presence of central depression, tumor grade G2, depth of invasion, LN swelling on preoperative imaging (cN1), venous invasion, and multiple NETs were risk factors for LN metastasis. LN metastasis was associated with poor disease-free and disease-specific survival.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Multidisciplinary Sciences
Kiyoun Yi, Gwang Ha Kim, Su Jin Kim, Cheol Woong Choi, Moon Won Lee, Bong Eun Lee, Geun Am Song
Summary: Endoscopic resection provides favorable long-term outcomes for d-NETs <= 10 mm in size, limited to the submucosal layer, and without lymph node or distant metastasis, when endoscopically complete resection is achieved.
SCIENTIFIC REPORTS
(2023)
Article
Urology & Nephrology
Markus von Deimling, Marc Furrer, Laura S. Mertens, Andrea Mari, Noor van Ginkel, Mara Bacchiani, Moritz Maas, Renate Pichler, Roger Li, Marco Moschini, Alberto Bianchi, Malte W. Vetterlein, Chiara Lonati, Felice Crocetto, Jacob Taylor, Karl H. Tully, Luca Afferi, Francesco Soria, Francesco del Giudice, Mattia Longoni, Ekaterina Laukhtina, Alessandro Antonelli, Michael Rink, Margit Fisch, Yair Lotan, Philippe E. Spiess, Peter C. Black, Bernhard Kiss, Benjamin Pradere, Shahrokh F. Shariat
Summary: In patients with clinically lymph node-positive bladder cancer, extended pelvic lymph node dissection did not improve recurrence-free survival or overall survival compared to standard pelvic lymph node dissection, regardless of induction chemotherapy.
Review
Medicine, General & Internal
Ralph F. Staerkle, Raphael Nicolas Vuille-dit-Bille, Christopher Soll, Rebekka Troller, Jaswinder Samra, Milo A. Puhan, Stefan Breitenstein
Summary: There is no evidence of an impact on survival with extended versus standard lymph node resection. However, the operating time may have been longer and blood loss greater in the extended resection group. Current evidence neither supports nor refutes the effect of extended lymph lymphadenectomy in people with adenocarcinoma of the head of the pancreas.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Gastroenterology & Hepatology
Jonathan Ragheb, Shruti Mony, Jason Klapman, Tolga Erim, Angela Reagan, Robert Butler, Yanbin Dong, Michael Cruise, Barbara A. Centeno, Pablo Bejarano, Tyler Stevens, Umar Hayat, Amit Bhatt
Summary: The study suggests that the main predictor of recurrence in low-grade DNETs <1.0 cm is the presence of positive tumor margins at the initial endoscopic resection. Ninety-two percent of recurrences were detected within 3 years of resection, indicating the need for more frequent, earlier surveillance. No recurrences occurred in the cohort after 4 years of surveillance.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Reproductive Biology
Pim Laven, Roy Kruitwagen, Petra Zusterzeel, Brigitte Slangen, Toon van Gorp, Jochem van der Pol, Sandrina Lambrechts
Summary: The study showed that performing SLN procedure after resection of the tumor seems to be less effective in detecting sentinel nodes compared to injecting the tracer in the ovarian ligaments before tumor resection.
JOURNAL OF OVARIAN RESEARCH
(2021)
Article
Oncology
Andra Nica, Zbigniew Marchocki, Lilian T. Gien, Rachel Kupets, Danielle Vicus, Allan Covens
Summary: This study found that cervical conization with SLN biopsy is a safe treatment option for selected patients with early cervical cancer. Patients had good oncologic, fertility, and obstetric outcomes post-surgery.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Article
Surgery
Haydee Del Calvo, Duc T. Nguyen, Edward Y. Chan, Ray Chihara, Edward A. Graviss, Min P. Kim
Summary: This study analyzed the National Cancer Database to determine the optimal surgical resection for patients with typical carcinoid tumors. The results showed that anatomic resection compared to wedge resection was associated with improved survival in patients with early-stage typical carcinoid lung cancer.
JOURNAL OF SURGICAL RESEARCH
(2022)
Review
Urology & Nephrology
Muhannad Alsyouf, Siamak Daneshmand
Summary: Testicular germ cell tumors (GCTs) are the most common malignancy among young males. The majority of patients present with early stages of the disease that are highly curable. Primary retroperitoneal lymph node dissection (RPLND) has been shown to be effective for low-volume metastatic GCT, providing an alternative to systemic chemotherapy.
EUROPEAN UROLOGY FOCUS
(2023)
Article
Cardiac & Cardiovascular Systems
Soh Hosoba, Toshiaki Ito, Makoto Mori, Riku Kato, Koh Kajiyama, Shogo Maeda, Yuji Nakai, Yoshihiro Morishita
Summary: This study describes the approach and perioperative outcomes of totally endoscopic isolated and concomitant surgical aortic valve replacement (AVR) using various valve types. The results demonstrate that endoscopic AVR can safely address concomitant valve diseases.
ANNALS OF THORACIC SURGERY
(2024)