Didehydro-Cortistatin A: a new player in HIV-therapy?

A Hardwired HIV Latency Program

(2015) Brandon S. Razooky et al.   CELL

HIV therapeutic vaccines: moving towards a functional cure

(2015) Geetha H Mylvaganam et al.   CURRENT OPINION IN IMMUNOLOGY

The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency

(2015) Guillaume Mousseau et al.   mBio

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

(2014) Courtney V. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triptolide inhibits human immunodeficiency virus type 1 replication by promoting proteasomal degradation of Tat protein

(2014) Zhitao Wan et al.   Retrovirology

Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy

(2014) Mary F. Kearney et al.   PLoS Pathogens

Blocking HIV-1 Replication by Targeting the Tat-Hijacked Transcriptional Machinery

(2013) Serena Massari et al.   CURRENT PHARMACEUTICAL DESIGN

Increase in 2–Long Terminal Repeat Circles and Decrease in D-dimer After Raltegravir Intensification in Patients With Treated HIV Infection: A Randomized, Placebo-Controlled Trial

(2013) Hiroyu Hatano et al.   JOURNAL OF INFECTIOUS DISEASES

Cellular and molecular mechanisms involved in the establishment of HIV-1 latency

(2013) Daniel A Donahue et al.   Retrovirology

Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study

(2013) Asier Sáez-Cirión et al.   PLoS Pathogens

An Analog of the Natural Steroidal Alkaloid Cortistatin A Potently Suppresses Tat-Dependent HIV Transcription

(2012) Guillaume Mousseau et al.   Cell Host & Microbe

The Viral Protein Tat Can Inhibit the Establishment of HIV-1 Latency

(2012) D. A. Donahue et al.   JOURNAL OF VIROLOGY

The Control of HIV Transcription: Keeping RNA Polymerase II on Track

(2011) Melanie Ott et al.   Cell Host & Microbe

HIV reservoirs and the possibility of a cure for HIV infection

(2011) S. Palmer et al.   JOURNAL OF INTERNAL MEDICINE

Celastrol Inhibits Tat-Mediated Human Immunodeficiency Virus (HIV) Transcription and Replication

(2011) Vivek Narayan et al.   JOURNAL OF MOLECULAR BIOLOGY

Scalable Synthesis of Cortistatin A and Related Structures

(2011) Jun Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The molecular biology of HIV latency: breaking and restoring the Tat-dependent transcriptional circuit

(2010) Jonathan Karn   Current Opinion in HIV and AIDS

15-Deoxy-Δ12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification

(2009) Parisa Kalantari et al.   FASEB JOURNAL

Modeling HIV persistence, the latent reservoir, and viral blips

(2009) Libin Rong et al.   JOURNAL OF THEORETICAL BIOLOGY

Latently-infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activity

(2009) Steven Yukl et al.   VIROLOGY