Is there potential to target FOXM1 for ‘undruggable’ lung cancers?

Dragging Ras Back in the Ring

(2014) Andrew G. Stephen et al.   CANCER CELL

Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition

(2014) Michael V. Gormally et al.   Nature Communications

Novel agents in development for advanced non-small cell lung cancer

(2014) Thomas E. Stinchcombe   Therapeutic Advances in Medical Oncology

Foxm1 transcription factor is required for the initiation of lung tumorigenesis by oncogenic KrasG12D

(2013) I-C Wang et al.   ONCOGENE

Targeting FOXM1 in cancer

(2012) Marianna Halasi et al.   BIOCHEMICAL PHARMACOLOGY

Foxm1 Mediates Cross Talk between Kras/Mitogen-Activated Protein Kinase and Canonical Wnt Pathways during Development of Respiratory Epithelium

(2012) I.-C. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

FOXM1 Promotes Allergen-Induced Goblet Cell Metaplasia and Pulmonary Inflammation

(2012) X. Ren et al.   MOLECULAR AND CELLULAR BIOLOGY

Multiple faces of FoxM1 transcription factor

(2011) Tanya V. Kalin et al.   CELL CYCLE

Forkhead box M1 transcriptional factor is required for smooth muscle cells during embryonic development of blood vessels and esophagus

(2009) Vladimir Ustiyan et al.   DEVELOPMENTAL BIOLOGY

Deletion of Forkhead Box M1 Transcription Factor from Respiratory Epithelial Cells Inhibits Pulmonary Tumorigenesis

(2009) I-Ching Wang et al.   PLoS One

Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors

(2008) I-C Wang et al.   ONCOGENE