Membrane lipids as therapeutic targets for Parkinson’s disease: a possible link between Lewy pathology and membrane lipids

Lipid rafts involvement in the pathogenesis of Parkinson s disease

(2015) Shin-ichiro Kubo   Frontiers in Bioscience-Landmark

Glucocerebrosidase and Parkinson disease: Recent advances

(2015) Anthony H.V. Schapira   MOLECULAR AND CELLULAR NEUROSCIENCE

Aggregates feel the strain

(2015) Seung-Jae Lee et al.   NATURE

Gaucher-related synucleinopathies: The examination of sporadic neurodegeneration from a rare (disease) angle

(2015) S. Pablo Sardi et al.   PROGRESS IN NEUROBIOLOGY

Dietary Factors in the Etiology of Parkinson’s Disease

(2015) Zeynep S. Agim et al.   Biomed Research International

Metabolic and cellular bases of sphingolipidoses

(2015) Konrad Sandhoff   BIOCHEMICAL SOCIETY TRANSACTIONS

New functions of mitochondria associated membranes in cellular signaling

(2014) Alexander R. van Vliet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Arylsulphatase A activity in familial parkinsonism: a pathogenetic role?

(2014) Elena Antelmi et al.   JOURNAL OF NEUROLOGY

The prevalence of Parkinson's disease: A systematic review and meta-analysis

(2014) Tamara Pringsheim et al.   MOVEMENT DISORDERS

Lewy body disease and dementia with Lewy bodies

(2014) Kenji KOSAKA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome

(2013) Suzanne Lesage et al.   ANNALS OF NEUROLOGY

MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond

(2013) Jean E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Gangliosides and Gangliosidoses: Principles of Molecular and Metabolic Pathogenesis

(2013) K. Sandhoff et al.   JOURNAL OF NEUROSCIENCE

Altered ceramide acyl chain length and ceramide synthase gene expression in Parkinson's disease

(2013) Sarah K. Abbott et al.   MOVEMENT DISORDERS

Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease

(2013) Silke Appel-Cresswell et al.   MOVEMENT DISORDERS

Lysosomal impairment in Parkinson's disease

(2013) Benjamin Dehay et al.   MOVEMENT DISORDERS

A novel  -synuclein missense mutation in Parkinson disease

(2013) C. Proukakis et al.   NEUROLOGY

The Function of α-Synuclein

(2013) Jacob T. Bendor et al.   NEURON

Niemann-Pick disease type C1 predominantly involving the frontotemporal region, with cortical and brainstem Lewy bodies: An autopsy case

(2013) Yoichi Chiba et al.   NEUROPATHOLOGY

Dietary fat intake, pesticide use, and Parkinson's disease

(2013) Freya Kamel et al.   PARKINSONISM & RELATED DISORDERS

Extensive aggregation of α-synuclein and tau in juvenile-onset neuroaxonal dystrophy: an autopsied individual with a novel mutation in the PLA2G6 gene-splicing site

(2013) Yuichi Riku et al.   Acta Neuropathologica Communications

Parkinson’s disease is not associated with gastrointestinal myenteric ganglion neuron loss

(2012) Dana M. Annerino et al.   ACTA NEUROPATHOLOGICA

Where the endoplasmic reticulum and the mitochondrion tie the knot: The mitochondria-associated membrane (MAM)

(2012) Arun Raturi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ambroxol as a pharmacological chaperone for mutant glucocerebrosidase

(2012) Inna Bendikov-Bar et al.   BLOOD CELLS MOLECULES AND DISEASES

Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans

(2012) Gusheng Wu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Structural Intermediates during α-Synuclein Fibrillogenesis on Phospholipid Vesicles

(2012) Gemma Comellas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A randomized, controlled, delayed start trial of GM1 ganglioside in treated Parkinson's disease patients

(2012) Jay S. Schneider et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The link between the GBA gene and parkinsonism

(2012) Ellen Sidransky et al.   LANCET NEUROLOGY

GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology

(2012) D. Tsuang et al.   NEUROLOGY

Proteomic analysis of lipid raft-enriched membranes isolated from internal organelles

(2011) Chloe N. Poston et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

(2011) Joseph R. Mazzulli et al.   CELL

Synuclein deposition and non-motor symptoms in Parkinson disease

(2011) Kurt A. Jellinger   JOURNAL OF THE NEUROLOGICAL SCIENCES

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(2011) Noemi Fabelo et al.   MOLECULAR MEDICINE

Lysosomal storage disorders and Parkinson's disease: Gaucher disease and beyond

(2011) Tamar Shachar et al.   MOVEMENT DISORDERS

CNS expression of glucocerebrosidase corrects  -synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy

(2011) S. P. Sardi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disorders

(2010) Ozlem Goker-Alpan et al.   ACTA NEUROPATHOLOGICA

Common and Uncommon Pathogenic Cascades in Lysosomal Storage Diseases

(2010) Einat B. Vitner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease

(2010) Lonnie Schneider et al.   Molecular Neurodegeneration

Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations

(2010) Coro Paisán-Ruiz et al.   NEUROBIOLOGY OF AGING

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

Parkinson's disease: Insights from non-traditional model organisms

(2010) Ilse S. Pienaar et al.   PROGRESS IN NEUROBIOLOGY

Mutations for Gaucher Disease Confer High Susceptibility to Parkinson Disease

(2009) Jun Mitsui et al.   ARCHIVES OF NEUROLOGY

Formation and development of Lewy pathology: a critical update

(2009) Kurt A. Jellinger   JOURNAL OF NEUROLOGY

Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: A biological link between Gaucher disease and parkinsonism

(2009) Amy B. Manning-Boğ et al.   NEUROTOXICOLOGY

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

(2009) E. Sidransky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neuropathology of non-motor features of Parkinson disease

(2009) Dennis W. Dickson et al.   PARKINSONISM & RELATED DISORDERS

Animal models of Parkinson’s disease progression

(2008) Gloria E. Meredith et al.   ACTA NEUROPATHOLOGICA

A critical reappraisal of current staging of Lewy-related pathology in human brain

(2008) Kurt A. Jellinger   ACTA NEUROPATHOLOGICA

A critical evaluation of the Braak staging scheme for Parkinson's disease

(2008) Robert E. Burke et al.   ANNALS OF NEUROLOGY

Depression in Parkinson's disease: A double-blind, randomized, placebo-controlled pilot study of omega-3 fatty-acid supplementation

(2008) Ticyana Moralez da Silva et al.   JOURNAL OF AFFECTIVE DISORDERS

Neurodegeneration associated with genetic defects in phospholipase A2

(2008) A. Gregory et al.   NEUROLOGY

Glucosidase-beta variations and Lewy body disorders

(2008) Matthew J. Farrer et al.   PARKINSONISM & RELATED DISORDERS

Management of non-motor symptoms in advanced Parkinson disease

(2007) Daniel D. Truong et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES