Direct Real-Time Monitoring of Prodrug Activation by Chemiluminescence

Development of a theranostic prodrug for colon cancer therapy by combining ligand-targeted delivery and enzyme-stimulated activation

(2018) Amit Sharma et al.   BIOMATERIALS

The emergence of aqueous chemiluminescence: new promising class of phenoxy 1,2-dioxetane luminophores

(2018) Samer Gnaim et al.   CHEMICAL COMMUNICATIONS

Chemiluminescence molecular probe with intrinsic auto-inductive amplification: incorporation of chemiexcitation in a quinone-methide elimination

(2018) Samer Gnaim et al.   CHEMICAL COMMUNICATIONS

Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics

(2018) Min Hee Lee et al.   CHEMICAL SOCIETY REVIEWS

ortho-Chlorination of phenoxy 1,2-dioxetane yields superior chemiluminescent probes for in vitro and in vivo imaging

(2018) Tal Eilon-Shaffer et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A chemiluminescent probe for cellular peroxynitrite using a self-immolative oxidative decarbonylation reaction

(2018) Jian Cao et al.   Chemical Science

Near-Infrared Dioxetane Luminophores with Direct Chemiluminescence Emission Mode

(2017) Ori Green et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Immolative Chemiluminescence Polymers: Innate Assimilation of Chemiexcitation in a Domino-like Depolymerization

(2017) Samer Gnaim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vivo bioluminescence imaging of labile iron accumulation in a murine model ofAcinetobacter baumanniiinfection

(2017) Allegra T. Aron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opening a Gateway for Chemiluminescence Cell Imaging: Distinctive Methodology for Design of Bright Chemiluminescent Dioxetane Probes

(2017) Ori Green et al.   ACS Central Science

In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation

(2016) Jian Cao et al.   ANALYTICAL CHEMISTRY

Remarkable Enhancement of Chemiluminescent Signal by Dioxetane–Fluorophore Conjugates: Turn-ON Chemiluminescence Probes with Color Modulation for Sensing and Imaging

(2016) Nir Hananya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Real-Time Tracking and In Vivo Visualization of β-Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe

(2016) Kaizhi Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Liposomal Texaphyrin Theranostics for Metastatic Liver Cancer

(2016) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dual-channel NIR activatable theranostic prodrug for in vivo spatiotemporal tracking thiol-triggered chemotherapy

(2016) Mingzhou Ye et al.   Chemical Science

Small conjugate-based theranostic agents: an encouraging approach for cancer therapy

(2015) Rajesh Kumar et al.   CHEMICAL SOCIETY REVIEWS

NIR Fluorogenic Dye as a Modular Platform for Prodrug Assembly: Real-Time in vivo Monitoring of Drug Release

(2015) Orit Redy-Keisar et al.   ChemMedChem

Chemiluminescent probes for imaging H2S in living animals

(2015) J. Cao et al.   Chemical Science

Sensitive β-galactosidase-targeting fluorescence probe for visualizing small peritoneal metastatic tumours in vivo

(2015) Daisuke Asanuma et al.   Nature Communications

An Activatable Theranostic for Targeted Cancer Therapy and Imaging

(2014) Sankarprasad Bhuniya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Personalised cancer medicine

(2014) Sarah E. Jackson et al.   INTERNATIONAL JOURNAL OF CANCER

In Vivo and in Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug

(2014) Xumeng Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A fluorescence off–on reporter for real time monitoring of gemcitabine delivery to the cancer cells

(2013) Sankarprasad Bhuniya et al.   CHEMICAL COMMUNICATIONS

Folate-Based Near-Infrared Fluorescent Theranostic Gemcitabine Delivery

(2013) Zhigang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gemcitabine–Coumarin–Biotin Conjugates: A Target Specific Theranostic Anticancer Prodrug

(2013) Sukhendu Maiti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation

(2013) Genevieve C. Van de Bittner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

“Donor–Two-Acceptor” Dye Design: A Distinct Gateway to NIR Fluorescence

(2012) Naama Karton-Lifshin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-Specific, Activatable, and Theranostic Prodrug for Dual-Targeted Cancer Imaging and Therapy

(2011) Santimukul Santra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Unique Paradigm for a Turn-ON Near-Infrared Cyanine-Based Probe: Noninvasive Intravital Optical Imaging of Hydrogen Peroxide

(2011) Naama Karton-Lifshin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Real-time monitoring of drug release

(2009) Roy Weinstain et al.   CHEMICAL COMMUNICATIONS

Enabling personalized cancer medicine through analysis of gene-expression patterns

(2008) Laura J. van 't Veer et al.   NATURE