Plazomicin: an investigational therapy for the treatment of urinary tract infections

In vitro bactericidal activity of aminoglycosides, including the next-generation drug plazomicin, against Brucella spp.

(2015) Steven C. Olsen et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Carbapenem-Resistant Klebsiella pneumoniae Strains Exhibit Diversity in Aminoglycoside-Modifying Enzymes, Which Exert Differing Effects on Plazomicin and Other Agents

(2014) Reem Almaghrabi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of Plazomicin against 5,015 Gram-Negative and Gram-Positive Clinical Isolates Obtained from Patients in Canadian Hospitals as Part of the CANWARD Study, 2011-2012

(2014) A. Walkty et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Plazomicin

(2014) I. Galani   DRUGS OF THE FUTURE

Multidrug-resistant and extensively drug-resistant Gram-negative pathogens: current and emerging therapeutic approaches

(2014) Ilias Karaiskos et al.   EXPERT OPINION ON PHARMACOTHERAPY

Aminoglycoside therapy in infectious diseases

(2013) Panagiotis Poulikakos et al.   EXPERT OPINION ON PHARMACOTHERAPY

Carbapenemases in Klebsiella pneumoniae and Other Enterobacteriaceae: an Evolving Crisis of Global Dimensions

(2012) L. S. Tzouvelekis et al.   CLINICAL MICROBIOLOGY REVIEWS

Exogenously acquired 16S rRNA methyltransferases found in aminoglycoside-resistant pathogenic Gram-negative bacteria: An update

(2012) Jun-ichi Wachino et al.   DRUG RESISTANCE UPDATES

Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin

(2012) George G Zhanel et al.   Expert Review of Anti-Infective Therapy

Activity of Plazomicin (ACHN-490) against MDR clinical isolates ofKlebsiella pneumoniae, Escherichia coli, andEnterobacterspp. from Athens, Greece

(2012) Irene Galani et al.   JOURNAL OF CHEMOTHERAPY

Activity of ACHN-490 Tested Alone and in Combination with Other Agents against Pseudomonas aeruginosa

(2011) Glenn A. Pankuch et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics and Safety of Single and Multiple Doses of ACHN-490 Injection Administered Intravenously in Healthy Subjects

(2011) Robert T. Cass et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Prevalence of 16S rRNA methylase genes in Enterobacteriaceae isolates from a Greek University Hospital

(2011) I. Galani et al.   CLINICAL MICROBIOLOGY AND INFECTION

Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance

(2011) A.-P. Magiorakos et al.   CLINICAL MICROBIOLOGY AND INFECTION

Activity of ACHN-490 against meticillin-resistant Staphylococcus aureus (MRSA) isolates from patients in US hospitals

(2011) Fred C. Tenover et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Antistaphylococcal Activity of ACHN-490 Tested Alone and in Combination with Other Agents by Time-Kill Assay

(2010) G. Lin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and Spectrum of the Neoglycoside ACHN-490

(2010) J. B. Aggen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Combating evolution with intelligent design: the neoglycoside ACHN-490

(2010) Eliana S Armstrong et al.   CURRENT OPINION IN MICROBIOLOGY

Activity of aminoglycosides, including ACHN-490, against carbapenem-resistant Enterobacteriaceae isolates

(2010) D. M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antimicrobial activity of a novel aminoglycoside, ACHN-490, against Acinetobacter baumannii and Pseudomonas aeruginosa from New York City

(2010) D. Landman et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Activity of a novel aminoglycoside, ACHN-490, against clinical isolates of Escherichia coli and Klebsiella pneumoniae from New York City

(2010) D. Landman et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In Vitro Activity of NXL104 in Combination with  -Lactams against Klebsiella pneumoniae Isolates Producing KPC Carbapenemases

(2009) A. Endimiani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES