Article
Multidisciplinary Sciences
Sebastian Roth, Henrik Fox, Rene M'Pembele, Michiel Morshuis, Giovanna Lurati Buse, Markus W. Hollmann, Ragnar Huhn, Thomas Bitter
Summary: Noninvasive pulse contour analysis (NPCA) using the CNAP Monitor was tested for its feasibility in heart transplant and left ventricular assist device (LVAD) patients. The results showed that NPCA was not suitable for noninvasive evaluation of hemodynamic status.
Article
Physiology
Alexander Reshetnik, Jonida Gjolli, Markus van der Giet, Friederike Compton
Summary: Invasive thermodilution techniques are still the gold standard for cardiac output measurement, but there is a growing need for non-invasive techniques to simplify the process. A novel oscillometry-based CO estimation method was evaluated and found to have some level of agreement with transpulmonary thermodilution in certain circumstances.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Anesthesiology
Ramakrishna Mukkamala, Benjamin A. Kohl, Aman Mahajan
Summary: The study compared the accuracy of two CO monitors using different pulse contour analysis methods in patients undergoing off-pump coronary artery bypass surgery, with the Argos device found to be more accurate than the Vigileo-FloTrac device in CO trending and absolute CO measurement.
BMC ANESTHESIOLOGY
(2021)
Article
Materials Science, Ceramics
Ruizhi Wang, Enling Tang, Guolai Yang, Yafei Han, Chuang Chen, Mengzhou Chang, Kai Guo, Liping He
Summary: This research studies the discharge characteristics of PZT under high-pressure stress pulses and the effect of different circuits on its electrical output. The critical open-circuit measurement resistance (Rcritial) of PZT decreases with stress frequency, and the output voltage is positively correlated with load resistance. Experiments confirm a reverse positive charge appearing at the negative pole of the material during stress unloading.
CERAMICS INTERNATIONAL
(2022)
Review
Cardiac & Cardiovascular Systems
Pedram Hassan-Tash, Umar Ismail, Iain D. C. Kirkpatrick, Amir Ravandi, Davinder S. Jassal, Brett Hiebert, Malek Kass, Richard A. Krasuski, Ashish H. Shah
Summary: Cardiac output (CO) and other hemodynamic parameters are important in the management of cardiovascular conditions, but current technologies have limitations in measuring these parameters. This study aimed to validate a non-invasive cardiac system (NICaS) that derives stroke volume (SV) using total-body impedance cardiography and compare it with cardiac magnetic resonance (CMR), the gold standard method. The results showed strong correlation and agreement between NICaS-derived SV and CMR-derived SV, suggesting that this technology can non-invasively detect hemodynamic changes at different time points.
CURRENT PROBLEMS IN CARDIOLOGY
(2023)
Article
Anesthesiology
Irwin Gratz, Martin Baruch, Ahmed Awad, Brian McEniry, Isabel Allen, Julia Seaman
Summary: The study evaluated the performance of the noninvasive Vitalstream (VS) continuous physiological monitor in comparison to thermodilution cardiac output during cardiac surgery. The results showed a clinically acceptable agreement between the two methods, indicating the potential of the VS monitor in expanding access to effective fluid management monitoring tools.
BMC ANESTHESIOLOGY
(2023)
Review
Engineering, Biomedical
Daniel Barvik, Martin Cerny, Marek Penhaker, Norbert Noury
Summary: Noninvasive continuous blood pressure estimation is a promising method for long-term and continuous blood pressure monitoring in ecological situations. The current estimation algorithm is based on pulse transit time measurement, but requires calibration to minimize error. Recent research focuses on simplified arterial properties, but there is a need for more complete calibration models.
IEEE REVIEWS IN BIOMEDICAL ENGINEERING
(2022)
Proceedings Paper
Computer Science, Artificial Intelligence
Priya Darshini Kumari, Ksh Milan Singh, Mayaluri Zefree Lazarus, Sujeevan Kumar Agir
Summary: Cardiac Output (CO) is a crucial parameter to be monitored continuously during critical surgeries like liver transplantation. While traditional methods for monitoring CO are invasive, Impedance Cardiography (ICG) has gained popularity as a non-invasive alternative. The efficacy and reliability of ICG, however, have been subjects of debate.
2021 IEEE INTERNATIONAL CONFERENCE ON INTELLIGENT SYSTEMS, SMART AND GREEN TECHNOLOGIES (ICISSGT 2021)
(2021)
Article
Anesthesiology
Amon Heijne, Piet Krijtenburg, Andre Bremers, Gert Jan Scheffer, Ignacio Malagon, Cornelis Slagt
Summary: In this study, the accuracy of cardiac index (CI) measurements derived from different methods during high-risk surgeries like cytoreductive surgery and hyperthermic intraperitoneal chemotherapy was investigated. The ClearSight, FloTrac, and ProAQT systems were found to be unreliable in measuring CI compared to transpulmonary thermodilution (TPTD) during these procedures, with unsatisfactory reproducibility of changes over time.
KOREAN JOURNAL OF ANESTHESIOLOGY
(2021)
Article
Anesthesiology
Yuefu Wang, Weiqin Huang, Jiange Han, Yu Tian, Chunrong Wang, Lihuan Li
Summary: This study conducted a multi-center clinical study in China to test the equivalence of cardiac output measured with the ClearSight system and the pulmonary artery catheter bolus thermodilution method. The results showed that the ClearSight system is equivalent to the pulmonary artery catheter bolus thermodilution method in measuring cardiac output in cardiac surgery patients.
PERIOPERATIVE MEDICINE
(2022)
Article
Engineering, Electrical & Electronic
Konstantinos Patmanidis, Tobias Kist, Michael Glavanovics, Annette Muetze
Summary: This paper introduces an open loop current source gate driver (CSGD) with adjustable gate voltage that can be software programmed to enable variable turn on/off speeds without manual adjustment. It also discusses the need for further investigation of potential new failure mechanisms for newly developed silicon (Si) power devices, as well as evaluating hard switching speeds.
MICROELECTRONICS RELIABILITY
(2021)
Article
Anesthesiology
Musashi Yahagi, Kyuma Omi, Takuma Maeda
Summary: This study aimed to examine the accuracy of non-invasive cardiac output (CO) measurement in patients with severe aortic stenosis (AS). The results showed that the accuracy and trending ability of the ClearSight CO measurements were not acceptable in these patients, and therefore cannot replace the pulmonary artery catheter (PAC) thermodilution method.
KOREAN JOURNAL OF ANESTHESIOLOGY
(2022)
Article
Anesthesiology
Evgeniia Fot, Alexey A. Smetkin, Dmitriy A. Volkov, Tatyana N. Semenkova, Konstantin Paromov, Vsevolod V. Kuzkov, Mikhail Y. Kirov
Summary: The reliability of measuring cardiac index (CI) and stroke-volume variation (SVV) using the pulse-wave transit-time (PWTT) method was compared with conventional pulse-contour analysis after off-pump coronary artery bypass grafting (OPCAB). The study found that the PWTT algorithm for measuring CI and SVV was not accurate and precise compared to pulse-contour analysis.
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2023)
Article
Critical Care Medicine
Malini Premkumar Joshi, Resham Rathod, Shilpushp Jagannath Bhosale, Atul Prabhakar Kulkarni
Summary: This study compared the performance of continuous cardiac output measurement methods, esCCO and FloTrac, and found significant correlation between the stroke volume index and cardiac index measured by the two methods. Although esCCO showed some degree of underestimation compared to FloTrac in certain parameters, the limits of agreement and percentage error were clinically acceptable, suggesting the potential advantage of esCCO in measuring cardiac output.
INDIAN JOURNAL OF CRITICAL CARE MEDICINE
(2022)
Article
Engineering, Electrical & Electronic
Chuang Wang, Yan Lu, Xiuping Li, Rui P. Martins
Summary: This paper presents a dual-branch series-parallel hybrid buck converter with flying capacitor voltage auto-balancing and reduced output impedance. The converter balances the flying capacitor voltages automatically and reduces the output impedance to decrease conduction loss.
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS
(2022)
Review
Cardiac & Cardiovascular Systems
Davide Olivari, Daria De Giorgio, Lidia Irene Staszewsky, Francesca Fumagalli, Antonio Boccardo, Deborah Novelli, Martina Manfredi, Giovanni Babini, Anita Luciani, Laura Ruggeri, Aurora Magliocca, Davide Danilo Zani, Serge Masson, Angelo Belloli, Davide Pravettoni, Giuseppe Maiocchi, Roberto Latini, Giuseppe Ristagno
Summary: This study presents a novel porcine model of decompensated acute heart failure (AHF) that combines chronic and acute myocardial infarction, volume overload, and pressure overload. The model successfully replicates all typical clinical signs of AHF in a consistent and reproducible manner.
CARDIOVASCULAR DRUGS AND THERAPY
(2022)
Article
Physiology
Emanuele Rezoagli, Aurora Magliocca, Domenico Luca Grieco, Giacomo Bellani, Giuseppe Ristagno
Summary: In this study, animals undergoing mechanical chest compressions had lower levels of exhaled CO2 signal compared to animals receiving manual chest compressions. The Airway opening index (AOI) was negatively correlated with intrathoracic pressure swings, lung density, and respiratory system compliance. Animals with CPR-associated lung edema had lower levels of AOI.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Julia M. Rosenbloom, Elizabeth De Souza, Felipe D. Perez, James Xie, Maria Suarez-Nieto, Ellen Wang, T. Anthony Anderson
Summary: Inequitable variability in healthcare practice negatively affects patient outcomes, particularly in the perioperative period for children of color. Our study found that Asian children had lower odds of receiving opioids and having moderate-severe pain postoperatively compared to White non-Hispanic children.
JOURNAL OF RACIAL AND ETHNIC HEALTH DISPARITIES
(2023)
Article
Anesthesiology
Alice Kate Cummings Joyner, Michael R. King, Conrad Safranek, Gomathy Parvathinathan, Elizabeth De Souza, T. Anthony Anderson
Summary: Prolonged opioid use after surgery (POUS) increases healthcare costs and utilization in adults. This study investigates the economic burden of POUS in adolescent patients and finds that adolescents with POUS have higher healthcare costs and utilization compared to non-POUS patients.
ANESTHESIA AND ANALGESIA
(2023)
Article
Anesthesiology
Micaela Q. Dugan, T. Anthony Anderson, Elizabeth De Souza, Jorge R. Delgado
Summary: Results from this exploratory survey indicate that CPSP is a significant problem for children undergoing surgery across various specialties, with considerable impact on patient well-being even years after surgery.
JOURNAL OF ANESTHESIA
(2022)
Correction
Anesthesiology
Micaela Q. Dugan, Jorge R. Delgado, Elizabeth De Souza, T. Anthony Anderson
JOURNAL OF ANESTHESIA
(2022)
Letter
Anesthesiology
Micaela Q. Dugan, T. Anthony Anderson
JOURNAL OF ANESTHESIA
(2022)
Article
Clinical Neurology
Isha Thapa, Elizabeth De Souza, Andrew Ward, Nicholas Bambos, Thomas Anthony Anderson
Summary: Chronic pain is a significant public health issue, and its occurrence after pediatric surgeries is not well understood. This study examined the incidence and risk factors of chronic pain after the 20 most common pediatric surgeries in different age groups. The results showed varying rates of chronic pain after surgery across different age groups, with certain surgeries and patient variables being associated with a higher risk.
Article
Anesthesiology
Ziyu Gan, Julia M. Rosenbloom, Elizabeth De Souza, T. Anthony Anderson
Summary: A retrospective cohort study found that Asian, Black, and Hispanic children of certain age groups were more likely to receive general anesthesia during magnetic resonance imaging (MRI) scans compared to White children. This phenomenon may indicate disparate care for children based on their race/ethnicity.
ANESTHESIA AND ANALGESIA
(2023)
Article
Anesthesiology
Thomas Anthony Anderson, Cholawat Pacharinsak, Jose Vilches-Moure, Husniye Kantarci, J. Bradley Zuchero, Kim Butts-Pauly, David Yeomans
Summary: Focused ultrasound can inhibit peripheral nerve nociceptive fibers, increase nociceptive thresholds and alter nerve structure in an animal model of acute pain. It has the potential as a peripheral nerve blockade technique for acute pain management.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Review
Polymer Science
Emma J. Murphy, Gustavo Waltzer Fehrenbach, Ismin Zainol Abidin, Ciara Buckley, Therese Montgomery, Robert Pogue, Patrick Murray, Ian Major, Emanuele Rezoagli
Summary: The prevention and treatment of diseases require effective functioning immune systems, which can be achieved by eliminating infections and abnormal cells. Immune or biological therapy can stimulate or inhibit the immune system depending on the circumstances. Polysaccharides, abundant biomacromolecules in plants, animals, and microbes, interact with and affect the immune response, playing a crucial role in treating various human illnesses. There is an urgent need to identify natural biomolecules that can prevent infection and treat chronic diseases. This article discusses the therapeutic potential of naturally occurring polysaccharides, extraction methods, and immunological modulatory capabilities.
Article
Medicine, General & Internal
Matteo Pozzi, Claudio Ripa, Valeria Meroni, Daniela Ferlicca, Alice Annoni, Marta Villa, Maria Grazia Strepparava, Emanuele Rezoagli, Simone Piva, Alberto Lucchini, Giacomo Bellani, Giuseppe Foti
Summary: ICU survivors may suffer from long-term physical and psychological impairments, and memories from the critical illness can influence their long-term psychological outcome. However, the role of ICU memories in COVID-19 critically ill patients is not yet known. A prospective observational study was conducted to investigate patients' memories from the critical illness experience and their association with a six-month psychological outcome and quality of life evaluation. The lack of pre-ICU memories was found to be an independent predictor of worse psychological outcomes in terms of anxiety, depression, and Post-traumatic Stress Disorder (PTDS). Understanding the factors associated with long-term outcomes in ICU survivors, including their experiences before ICU admission, is crucial.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Alice Nova, Emanuele Rezoagli, Nilde Eronia, Annalisa Benini, Andrea Scognamiglio, Giuseppe Foti, Giacomo Bellani
Summary: This study aimed to evaluate the predictive performance of the combination of LUSS and ROX indices in patients with hypoxemia due to COVID-19 pneumonia. The results showed that the LUSS/ROX index had higher accuracy in predicting negative outcomes compared to the LUSS index.
Article
Anesthesiology
Aurora Magliocca, Carlo Perego, Francesca Motta, Giulia Merigo, Edoardo Micotti, Davide Olivari, Francesca Fumagalli, Jacopo Lucchetti, Marco Gobbi, Alessandra Mandelli, Roberto Furlan, Markus B. Skrifvars, Roberto Latini, Giacomo Bellani, Fumito Ichinose, Giuseppe Ristagno
Summary: The modulation of the kynurenine pathway through genetic deletion of the rate-limiting enzyme indoleamine 2,3-dioxygenase may have a protective effect on post-cardiac arrest brain injury, as shown by improved survival, neurologic function, and brain microintegrity.
Meeting Abstract
Anesthesiology
Thomas A. Anderson, Alice Joyner, Michael R. King, Conrad Safranek, Gomathy Parvathinathan, Beth De Souza
ANESTHESIA AND ANALGESIA
(2022)