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Chemistry, Analytical
Fan He, Jinyi Yang, Tingting Zou, Zhenlin Xu, Yuanxin Tian, Wenjia Sun, Hong Wang, Yuanming Sun, Hongtao Lei, Zijian Chen, Juewen Liu, Xuecai Tan, Yudong Shen
Summary: A gold nanoparticle-based immunochromatographic assay was developed for simultaneous detection of sildenafil and its analogues, with qualitative and quantitative analysis capabilities in a rapid manner.
ANALYTICA CHIMICA ACTA
(2021)
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Food Science & Technology
Zehua Xu, Tieqiang Sun, Hongwei He, Wentao Liu, Longxing Fan, Lingdi Zhao, Xinglin Wu, Zhenyu Han, Yingcun Zhang, Qiangqiang Wang, Baoan Ning, Zhixian Gao
Summary: An immunochromatographic assay based on competitive format was developed for rapid and sensitive detection of DES and E-2 in milk and tissue samples. The method showed good specificity, simple procedure, and low cost compared with the HPLC-MS / MS method, making it suitable for food safety monitoring and early warning.
FOOD SCIENCE & NUTRITION
(2021)
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Chemistry, Analytical
Yuan Cheng, Wenliang Ge, Hua Kuang, Jianping Zhu, Liqiang Liu, Yingyue Zhu, Chuanlai Xu
Summary: A highly sensitive and specific monoclonal antibody was developed for KCZ detection in chicken samples, with a visual limit of detection of 0.5 ng/g. The CGIA method shows great potential for rapidly detecting KCZ residues in chicken samples, with results revealed in only 10 minutes.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Xiaoling Li, Xinxin Xu, Aihong Wu, Shanshan Song, Hua Kuang, Liqiang Liu, Zhengyou Wang, Chuanlai Xu
Summary: An antibody and two detection methods (ic-ELISA and ICA) were developed for the detection of phenolphthalein in slimming products. These methods showed high sensitivity and a wide detection range, enabling rapid and accurate detection of phenolphthalein.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Food Science & Technology
Youxue Wu, Meijiao Wu, Cheng Liu, Yachen Tian, Shuiqin Fang, Hao Yang, Bin Li, Qing Liu
Summary: The study has developed a rapid, simple, and sensitive colloidal gold immunochromatographic test strip for detecting Salmonella, with the ability to detect multiple strains within minutes, important for food safety.
Article
Chemistry, Analytical
Chunhui Lu, Si Li, Wei Jiang, Qi Liu, Xiaomei Wang, Chen Yang, Quan Wang
Summary: A rapid and sensitive fluorescence-based immunochromatographic test was developed to quantitatively determine chloramphenicol levels in three food products. The method demonstrated high detection sensitivity and specificity, and could be completed for field detection within 30 minutes.
ANALYTICAL METHODS
(2022)
Article
Engineering, Environmental
Lu Zeng, Xinxin Xu, Lingling Guo, Zhongxing Wang, Hongliu Ding, Shanshan Song, Liguang Xu, Hua Kuang, Liqiang Liu, Chuanlai Xu
Summary: A monoclonal antibody against histamine was prepared with high sensitivity for rapid detection in fish samples, which was confirmed to complete the testing process within 15 minutes and produce comparable results with liquid chromatography-mass spectrometry and commercial test strips.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Biochemistry & Molecular Biology
Xiuying Liu, Yuanyuan Cheng, Binbin Guan, Fei Xia, Ling Fan, Xue Gao, Xiaofei Sun, Xuepeng Li, Lijie Zhu
Summary: A multicolor immunochromatographic assay platform based on quantum dot nanobeads is developed for rapid and simultaneous detection of nitrofuran metabolites in aquatic products. The platform shows low detection limits, fast detection, and good stability and specificity.
Article
Chemistry, Analytical
Ming Li, Chenfei Han, Chuqin Yang, Mingna Sun, Jinsheng Duan, Xuchun Qiu, Daolin Du
Summary: A ultrasensitive fluorometric oligonucleotide immunoassay (UFOIA) based on a fluorometric oligonucleotide and magnetic separation was proposed for simultaneous detection of two mycotoxins, exhibiting improved sensitivities compared to ELISA.
ANALYTICAL METHODS
(2022)
Article
Chemistry, Applied
Ying Xu, Biao Ma, Erjing Chen, Xiaoping Yu, Zihong Ye, Chuanxin Sun, Mingzhou Zhang
Summary: A dual fluorescent immunochromatographic assay based on europium nanoparticles was developed for simultaneous detection of CIT and ZEN in corn samples, showing high sensitivity and accuracy.
Article
Chemistry, Analytical
Yimeng Pang, Zehao Yang, Xiaohua Liu, Xing Shen, Zhenlin Xu, Hongtao Lei, Hongwei Zhao, Xiangmei Li
Summary: Robustness is crucial for improving the analytical performance of immunochromatography. A novel composite nanocarrier has been developed in this study to enhance the sensitivity and robustness of traditional immunochromatographic assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Biochemical Research Methods
Yiyi Chen, Yanghong Shen, Haifeng Wang, Jinzhi Zhang, Junli Zhu
Summary: Due to universal contamination and synergistic toxicity of multiple mycotoxins in foodstuff, a novel dual-channel immunochromatographic assay (ICA) based on improved up-conversion nanoparticles (IUCNPs) was developed for rapidly detecting aflatoxin B1 (AFB1) and zearalenone (ZEN). The IUCNPs-ICA exhibited high specificity for the targeted mycotoxins, and showed excellent accuracy with low detection limits. The method also demonstrated good stability and precision during long-term storage, suggesting potential for on-site screening in agricultural products.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Peiyuan Cai, Rongzhi Wang, Sumei Ling, Shihua Wang
Summary: This study developed strip assays based on gold nanoparticles and gold nano-flowers for rapid detection of trace amounts of tenuazonic acid (TA), demonstrating high sensitivity and specificity.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Analytical
Shengyang Zhou, Liguang Xu, Hua Kuang, Jing Xiao, Chuanlai Xu
Summary: A rapid lateral flow fluorescence microsphere immunoassay test strip (FM-ICTS) was established for the detection of deoxynivalenol (DON) residues in agricultural products based on competitive immunoreactivity. The method, utilizing highly sensitive antibodies and fluorescent markers, is simple, reliable, and sensitive for food safety analysis.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Applied
Sha Chen, Tian Guan, Zhenjie Qian, Qiqi Quan, Jin Wang, Xiangmei Li, Shaozong Wu, Yiyong Yan, Xiaojun Yao, Shiwei Zhang, Hongtao Lei
Summary: In this study, a rapid and sensitive method for the detection of three stimulant laxatives in slimming foods was developed using a broad-specific and highly sensitive monoclonal antibody. The method showed qualitative and quantitative detection abilities with acceptable recoveries and consistent results with liquid chromatography with tandem mass spectrometry.
Article
Chemistry, Analytical
Gang Qu, Yuxin Zhao, Qiaoli Zhang, Jina Wu, Xiaosen Li, Yang Yang, Shilei Liu
Summary: In this study, magnetic mesoporous materials combined with real-time in situ mass spectrometry were used for the high-throughput detection of hydrolyzed products of organophosphorus nerve agents. The method showed good linearity, low limits of detection and quantification, and high extraction recoveries. The magnetic preparation method used was quick, cost-effective, rugged, and safe. The results demonstrated the potential of this method for rapid and efficient determination of the target analytes in environmental samples.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Anna Hildebrand, Mariam Merchant, Danny O'Hare
Summary: Substandard and falsified artemisinin derivatives in antimalarials have caused significant deaths and economic losses. This study evaluates the feasibility of voltammetric methods for identifying and quantifying artemether. The findings suggest that electrochemical analysis shows promise as a method for artemether identification and quantification.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Marx Osorio Araujo Pereira, Alvaro Ferreira Junior, Edson Silvio Batista Rodrigues, Helena Mulser, Giovanna Nascimento de Mello e Silva, Wallans Torres Pio dos Santos, Eric de Souza Gil
Summary: Brazilian spotted fever (BSF) is a serious and rapidly evolving disease. A new impedimetric immunosensor was developed for rapid diagnosis by measuring specific antibodies in plasma. The sensor demonstrated selectivity and accuracy, and has potential for important applications in diagnostic testing.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Kathrin Schilling, Ronald A. Glabonjat, Olgica Balac, Marta Galvez-Fernandez, Arce Domingo-Relloso, Vesna Slavkovich, Jeff Goldsmith, Miranda R. Jones, Tiffany R. Sanchez, Ana Navas-Acien
Summary: Analysis of trace elements in urine is an important tool for assessing exposures, diagnosing nutritional status, and guiding public health and healthcare intervention. This study provides a sensitive method for analyzing 18 elements in urine samples, using only 100 μL. The results show good accuracy and sensitivity of the method.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Mengya Li, Shijie Liu, Shiliang Guo, Dong Liang, Miaoyun Li, Yaodi Zhu, Lijun Zhao, Jong-Hoon Lee, Gaiming Zhao, Yangyang Ma, Yanxia Liu
Summary: In this study, a magnetic flow device was developed to purify spores in a culture medium system. The device used magnetic nanoparticles to absorb vegetative cells, separating them from the spores. The achieved purity of the collected spores was over 95%. The study also demonstrated a rapid quantitative detection method using Raman spectroscopy.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Wanqiong Liu, Zixuan Wu, Jianwei Peng, Zebin Xu, Yong Liang
Summary: Metal-organic frameworks (MOFs) are effective carriers for molecular imprinting, but their poor dispersibility in aqueous solution is a significant drawback. In this study, we have applied amphiphilic block copolymers and molecularly imprinted technology on MOFs to improve the hydrophilicity of molecularly imprinted fluorescent materials.
ANALYTICAL METHODS
(2024)
