High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

Published 2018 View Full Article

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Title
High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling
Authors
Keywords
Nucleotide exchange, SOS1, RAS, Small molecule, X-Ray structure, Agonist
Journal
ANALYTICAL BIOCHEMISTRY
Volume 548, Issue -, Pages 44-52
Publisher
Elsevier BV
Online
2018-02-11
DOI
10.1016/j.ab.2018.01.025

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