A rapid solution-based method for determining the affinity of heroin hapten-induced antibodies to heroin, its metabolites, and other opioids

The Effect of Fluorophore Conjugation on Antibody Affinity and the Photophysical Properties of Dyes

(2018) Ágnes Szabó et al.   BIOPHYSICAL JOURNAL

Determination of cross-reactivity of poly- and monoclonal antibodies for synthetic cannabinoids by direct SPR and ELISA

(2017) Nico Langer et al.   FORENSIC SCIENCE INTERNATIONAL

A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse

(2017) Agnieszka Sulima et al.   JOURNAL OF MEDICINAL CHEMISTRY

Heroin-HIV-1 (H2) vaccine: induction of dual immunologic effects with a heroin hapten-conjugate and an HIV-1 envelope V2 peptide with liposomal lipid A as an adjuvant

(2017) Oscar B. Torres et al.   npj Vaccines

Isothermal titration calorimetry for drug design: Precision of the enthalpy and binding constant measurements and comparison of the instruments

(2016) Vaida Linkuvienė et al.   ANALYTICAL BIOCHEMISTRY

A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuse

(2015) Oscar B. Torres et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Efficacy, but Not Antibody Titer or Affinity, of a Heroin Hapten Conjugate Vaccine Correlates with Increasing Hapten Densities on Tetanus Toxoid, but Not on CRM197 Carriers

(2015) Rashmi Jalah et al.   BIOCONJUGATE CHEMISTRY

Characterization and optimization of heroin hapten-BSA conjugates: method development for the synthesis of reproducible hapten-based vaccines

(2014) Oscar B. Torres et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Injection Route and TLR9 Agonist Addition Significantly Impact Heroin Vaccine Efficacy

(2014) Paul T. Bremer et al.   MOLECULAR PHARMACEUTICS

Facial recognition of heroin vaccine opiates: Type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine

(2014) Gary R. Matyas et al.   VACCINE

Global structures of IgG isotypes expressing identical variable regions

(2013) Ertan Eryilmaz et al.   MOLECULAR IMMUNOLOGY

Liposomes containing monophosphoryl lipid A: A potent adjuvant system for inducing antibodies to heroin hapten analogs

(2013) Gary R. Matyas et al.   VACCINE

Direct Detection of Antibody Concentration and Affinity in Human Serum Using Microscale Thermophoresis

(2012) Svenja Lippok et al.   ANALYTICAL CHEMISTRY

Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions

(2012) Susanne A.I. Seidel et al.   METHODS

Structural and immunologic characterization of bovine, horse, and rabbit serum albumins

(2012) Karolina A. Majorek et al.   MOLECULAR IMMUNOLOGY

Probing Cocaine-Antibody Interactions in Buffer and Human Serum

(2012) Muthu Ramakrishnan et al.   PLoS One

Molecular Interaction Studies Using Microscale Thermophoresis

(2011) Moran Jerabek-Willemsen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Carboxylesterase inhibitors

(2011) M. Jason Hatfield et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

A Vaccine Strategy that Induces Protective Immunity against Heroin

(2011) G. Neil Stowe et al.   JOURNAL OF MEDICINAL CHEMISTRY

Impact of Distinct Chemical Structures for the Development of a Methamphetamine Vaccine

(2011) Amira Y. Moreno et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Large shifts in pKa values of lysine residues buried inside a protein

(2011) D. G. Isom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Charges in the hydrophobic interior of proteins

(2010) D. G. Isom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Utility of the carboxylesterase inhibitorbis-para-nitrophenylphosphate (BNPP) in the plasma unbound fraction determination for a hydrolytically unstable amide derivative and agonist of the TGR5 receptor

(2010) H. Eng et al.   XENOBIOTICA

Few and Far Between: How HIV May Be Evading Antibody Avidity

(2010) Joshua S. Klein et al.   PLoS Pathogens