A novel malic acid-enhanced method for the analysis of 5-methyl-2′-deoxycytidine, 5-hydroxymethyl-2′-deoxycytidine, 5-methylcytidine and 5-hydroxymethylcytidine in human urine using hydrophilic interaction liquid chromatography-tandem mass spectrometry

Title
A novel malic acid-enhanced method for the analysis of 5-methyl-2′-deoxycytidine, 5-hydroxymethyl-2′-deoxycytidine, 5-methylcytidine and 5-hydroxymethylcytidine in human urine using hydrophilic interaction liquid chromatography-tandem mass spectrometry
Authors
Keywords
DNA and RNA modification, 5-Methylated and 5-hydroxymethylated cytosine nucleosides, Hydrophilic interaction liquid chromatography-tandem mass spectrometry, Malic acid, Colorectal cancer
Journal
ANALYTICA CHIMICA ACTA
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2018-07-03
DOI
10.1016/j.aca.2018.06.081

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