Article
Multidisciplinary Sciences
Khalid E. Alzahrani, Mahmoud Al-Gawati, Abdulaziz K. Assaifan, Abdullah Alodhayb, Khalid Alotaibi, Abdullah Alswieleh, Hamad Albrithen, Amal F. Alanazi
Summary: This study presents a novel approach based on microcantilever for measuring the level of vitamin D, using Bruno aptamer as a sensing layer. By measuring the changes in microcantilever deflection and frequency, the vitamin D concentration can be accurately detected with high selectivity.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Chemistry, Physical
Shringika Soni, Utkarsh Jain, Donald H. Burke, Nidhi Chauhan
Summary: Prescription stimulant drug (PSD) abuse is a global concern, and there is a need for the development of sensitive, rapid, and low-cost kits for on-spot PSD detection. In this study, a gold nanoflower modified, electrochemical aptasensor was successfully developed for Amphetamine (AMP) detection. The aptasensor showed high sensitivity, low limit of detection, and negligible interference from potentially interfering compounds. It was able to accurately detect AMP in spiked urine and water samples.
SURFACES AND INTERFACES
(2022)
Article
Engineering, Electrical & Electronic
Fahimeh Marvi, Kian Jafari
Summary: This paper presents a novel optical BioNEMS sensor based on a 1D photonic crystal structure, which can achieve label-free biosensing and early disease diagnosis with high sensitivity and mechanical characteristics.
IEEE SENSORS JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Najeeb Ullah, Beenish Noureen, Yulan Tian, Liping Du, Wei Chen, Chunsheng Wu
Summary: This study presents a label-free EIS sensor for the detection of Saxitoxin (STX), a highly toxic shellfish toxin. The sensor is convenient, desirable, and affordable, and demonstrates high selectivity and stability. It enables rapid and label-free detection of marine toxins.
Article
Spectroscopy
Hongjie Qi, Lixin Feng, Suixin Zhao, Haiyin Li, Feng Li
Summary: In this study, a novel method for antibiotic screening was developed, which enabled label-free, enzyme-free, and highly sensitive detection of target antibiotics. This method utilized an iridium (III) complex (Ir-QAU) that specifically intercalated in G-quadruplex (G4) DNA and restricted intra-molecular rotation, thereby achieving high sensitivity for target antibiotic detection. Successful application of this method in milk samples was demonstrated.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Beenish Noureen, Najeeb Ullah, Yulan Tian, Liping Du, Wei Chen, Chunsheng Wu, Ping Wang
Summary: This study developed an electrolyte-insulator semiconductor (EIS) sensor for the label-free detection of saxitoxin (STX), one of the most dangerous shellfish toxins. The sensor was covered with a layer of positively-charged weak polyelectrolyte and utilized a specific aptamer for STX detection. The results showed that the aptasensor had a low detection limit and good selectivity and stability. This sensor provides a convenient approach for the moderate, rapid, and label-free detection of marine biological toxins.
Article
Chemistry, Multidisciplinary
Yawei Wang, Lei Chen, Tiantian Xuan, Jian Wang, Xiuwen Wang
Summary: An integrated electrode system consisting of a graphene working electrode, a carbon counter electrode, and an Ag/AgCl reference electrode was fabricated for label-free detection of carcinoembryonic antigen. The linear relationship between CEA concentration (0.2-15.0 ng/ml) and impedance change was demonstrated, with a calculated detection limit of 0.085 ng/ml.
FRONTIERS IN CHEMISTRY
(2021)
Article
Multidisciplinary Sciences
Rugare G. Chingarande, Kai Tian, Yu Kuang, Aby Sarangee, Chengrui Hou, Emily Ma, Jarett Ren, Sam Hawkins, Joshua Kim, Ray Adelstein, Sally Chen, Kevin D. Gillis, Li- Qun Gu
Summary: Nucleic acids can undergo conformational changes upon binding small molecules, and a modular, label-free, nucleic acid-docked nanopore has been developed to detect these changes. By using specific ligands as testbeds, the nanopore tool can characterize the binding and release of ligand molecules from nucleic acids, providing potential for small molecule biosensing, drug discovery assayed via RNA and DNA conformational changes, and the design of artificial riboswitch effectors in synthetic biology.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Chemistry, Analytical
Jintao Liang, Fei Guo, Jiaying Huang, Xiaohong Tan, Lixian Sun, Zhide Zhou, Guiyin Li
Summary: An ultrasensitive label-free electrochemical aptasensing platform was constructed for the detection of GP73 protein in hepatocellular carcinoma.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Physical
Vo Thi Nhat Linh, Sang-Gu Yim, ChaeWon Mun, Jun-Yeong Yang, Seunghun Lee, Yeon Woo Yoo, Dong Kyung Sung, Yong-Ill Lee, Dong-Ho Kim, Sung-Gyu Park, Seung Yun Yang, Ho Sang Jung
Summary: A bioinspired nanoflower structure was fabricated on microneedle to serve as a surface-enhanced Raman scattering (SERS) sensor for intradermal sensing applications. The sensor was capable of detecting methylene blue down to a concentration of 50 nM and 1 nM in a skin phantom model.
APPLIED SURFACE SCIENCE
(2021)
Article
Food Science & Technology
Stefan Jaric, Aabha Bajaj, Vladimir Vukic, Ivana Gadjanski, Ibrahim Abdulhalim, Ivan Bobrinetskiy
Summary: In this study, a new method for label-free detection of cyanotoxin molecules using a graphene-modified surface plasmon resonance (SPR) aptasensor is reported. Molecular dynamic simulation reveals the strongest binding sites between the aptamer and cylindrospermopsin (CYN) are located between C18-C26 pairs. The SPR sensor was modified using the wet transfer method of CVD monolayer graphene. For the first time, graphene functionalized with an aptamer was used as a bioreceptor in conjunction with SPR for the detection of CYN, showing noticeable changes in the optical signal in response to concentrations below the maximum tolerable level of 1 μg/L and high specificity.
Article
Nanoscience & Nanotechnology
Tao Ming, Yan Cheng, Yu Xing, Jinping Luo, Gang Mao, Juntao Liu, Shuai Sun, Fanli Kong, Hongyan Jin, Xinxia Cai
Summary: The study introduces a paper-based aptasensor platform for convenient and affordable detection of biomarkers. Experimental results demonstrate its ability to accurately determine 17-beta-Estradiol in a wide concentration range and detect targets in clinical samples, showing its potential for various applications.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Eun Hye Koh, Won-Chul Lee, Yeong-Jin Choi, Joung-Il Moon, Jinah Jang, Sung-Gyu Park, Jaebum Choo, Dong-Ho Kim, Ho Sang Jung
Summary: A wearable SERS sensor has been developed for molecular sweat sensing, with the capability of measuring Raman signals without detachment from the skin. Through a multi-layer design, the sensor can absorb sweat, protect the skin, enhance signal, and has great potential for drug detection applications.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Applied
Li Wang, Hongsu Wang, Shuqing Huang, Fengling Wu, Xiaodi Niu
Summary: This study proposes an electrochemical sensor for the efficient detection of streptomycin in milk, using magnetic mesoporous carbon materials as a loaded material and unlabeled streptomycin aptamer as the identification element. The sensor demonstrates high sensitivity, wide detection range, and low detection limit, providing a rapid and sensitive method for streptomycin detection in milk.
Article
Chemistry, Analytical
Jianmei Yang, Xiaoyan Gan, Xinmei Song, Ruo Yuan, Yun Xiang
Summary: This article describes a label-free and highly sensitive method for detecting NGAL based on aptamer. The method utilizes metal ion-dependent DNAzyme and exonuclease III (Exo III) triggered signal amplification cascades to detect NGAL in diluted human serums. The biosensor shows high selectivity and has the potential to detect various protein biomarkers for disease diagnosis.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Physical
Yongpei Peng, Junhui Zhang, Weiwei Xue, Wenjie Wu, Yu Wang, Kainan Mei, Ye Chen, Depeng Rao, Tianhao Yan, Jianye Wang, Yunxia Cao, Shangquan Wu, Qingchuan Zhang
Summary: This study investigates the nanomechanical vibrations of oocytes at different developmental stages and reveals the characteristics of these vibrations, which are influenced by the cytoskeleton and mitochondrial distribution. The findings provide a new perspective for clinical quality assessment and basic research of oocytes, contributing to the advancement of life science.
Article
Chemistry, Physical
Yu Wang, Tianhao Yan, Kainan Mei, Depeng Rao, Wenjie Wu, Ye Chen, Yongpei Peng, Jianye Wang, Shangquan Wu, Qingchuan Zhang
Summary: This study developed an ultrasensitive nanomechanical method based on peptide nucleic acid for the detection of SARS-CoV-2 RNA. The method has a low detection limit and can accurately diagnose COVID-19 patients, making it an important tool for early diagnosis and broad detection.
Article
Materials Science, Multidisciplinary
Y. Liu, Z. Lv, Q. Zhang, J. Zhao, Z. Fang, Z. Gao, Y. Su
Summary: This study introduces several camera calibration methods that can achieve high measurement accuracy even with low-precision calibration boards. Experimental results show that the fixing 3-points method can restore the calibration board more accurately and improve reproducibility and measurement accuracy.
EXPERIMENTAL MECHANICS
(2023)
Article
Materials Science, Multidisciplinary
F. Wang, L. M. Lei, X. Fu, L. Shi, X. M. Luo, Z. M. Song, G. P. Zhang
Summary: The fatigue crack growth behavior of TA19 alloy and its heat-treated samples was investigated. The crack growth resistance in different regimes was determined by analyzing the interaction between the fatigue crack and alpha/beta phase interface, columnar prior-beta grain boundary, and colony boundary. The results showed that the crack propagation threshold and resistance increased with the increase of lamellar alpha(p) phase and colony width in the near-threshold regime. In the Paris regime, the fatigue cracking path could be deflected at colony boundaries or columnar prior-beta grain boundaries, and the deflection angle influenced the crack growth rate.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Jian-Zhi Chen, Bin Zhang, Zhu-Man Song, Guang-Ping Zhang
Summary: The biaxial tension-torsion in-phase fatigue properties of a welded joint and base material of an A588 steel train bogie were compared. The relation between equivalent stress amplitude and cyclic fatigue life was determined. Results show that the welded joint specimen has a higher fatigue life than the base material at higher stress amplitudes, but the two become closer at lower stress amplitudes. A critical stress range of 368 MPa to 396 MPa dominates the fatigue damage behavior of the welded joint. When stress amplitude exceeds the critical stress, fatigue crack initiation tends to occur at the boundary between the base material and heat-affected zone, while cracks originate from the weld metal zone under lower stress amplitudes. Comprehensive analysis of microstructure and residual stress distribution provides insights for optimizing fatigue performance of welded metallic components.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2023)
Article
Nanoscience & Nanotechnology
Mei-Yue Li, Zhe-Xuan Wang, Bin Zhang, Fei Liang, Xue-Mei Luo, Guang-Ping Zhang
Summary: This study investigated the fatigue strength of nanocrystalline Ni/Ni-W laminated composites. The results showed that the fatigue resistance of the Ni/Ni-W laminated composites was improved compared to monotonic Ni. Shear banding and voiding were identified as the two dominant modes of fatigue damage in the composites. A deformation map was proposed to explain the critical conditions and transition of shear bands and voids. The introduction of ultrathin Ni-W layers hindered crack propagation across the heterogeneous interface, leading to improved fatigue strength.
SCRIPTA MATERIALIA
(2023)
Article
Optics
Zheng Fang, Yaru Wang, Yang Liu, Liangliang Lv, Guangqiang Fang, Zeqian Lv, Zeren Gao, Yong Su, Qingchuan Zhang
Summary: In order to enhance the detection capability of satellite-based synthetic aperture radar, a large antenna array with a length scale of 100 meters is urgently required. However, the deformation of the antenna leads to phase errors, which significantly impacts the antenna gain. Therefore, real-time and high-precision profile measurements of the antenna are crucial for active compensation of the phase and improving the antenna gain. To address the challenges of in-orbit measurements, a three-dimensional displacement measurement method based on laser distance measuring and digital image correlation (DIC) is proposed. The method combines the DIC method and a laser range finder to retrieve in-plane displacement information and depth information respectively.
Article
Materials Science, Multidisciplinary
C. Zhu, Z. Gao, W. Xue, H. Tu, Q. Zhang
Summary: This paper proposes a new method to use strobe lighting to assist image reconstruction for event cameras, providing a cost-effective alternative for high-speed deformation measurements. The method achieves high temporal resolution and low data redundancy, while exhibiting remarkable adaptability to the motion speed of the object being measured.
EXPERIMENTAL MECHANICS
(2023)
Article
Materials Science, Multidisciplinary
Zhe-Xuan Wang, Fei Liang, Guang-Ping Zhang, Bin Zhang
Summary: This study successfully fabricated Ni/Ni-W laminated composites with different monolayer thicknesses and investigated their microstructure stability and tensile properties at 400 degrees C. The annealed Ni0.5/Ni-W0.05 laminated composites exhibited high yield strength and excellent elongation to failure at 400 degrees C, surpassing the monotonic Ni material. The high strength of the laminated composites at high temperatures is attributed to the intrinsic strength of the Ni-W layers, the thickness-constrained effect on grain growth of Ni layers, and the interface coupling effect of heterogeneous structures. The plasticity of the composites can be derived from the heterogeneous laminated structure and the decrease in the constituent layer thickness, providing good co-deformation ability.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Physical
Bing-Li Hu, Yan-Wen Luo, Bin Zhang, Guang-Ping Zhang
Summary: Fatigue life prediction of Inconel 718 fabricated by laser powder bed fusion was investigated using a miniature specimen tests method and machine learning algorithms. Among the thirteen popular machine learning algorithms investigated, the adaptive boosting algorithm exhibited the best fitting accuracy, followed by the decision tree algorithm. These results demonstrate the capability of using small dataset-based machine learning techniques to predict fatigue life.
Article
Nanoscience & Nanotechnology
Yongman Liu, Wenjie Wu, Shuo Feng, Ye Chen, Xiaoping Wu, Qingchuan Zhang, Shangquan Wu
Summary: This study visualizes the mechanical interactions between cells and the extracellular matrix (ECM) during osmotic shock by quantifying the dynamic evolution of cell traction force. It is found that both hypertonic and hypotonic shocks induce continuous and large changes in cell traction force, which varies with cell volume. The direction of the traction force, however, remains independent of cell volume changes and is always toward the center of the cell-substrate interface. These findings provide new insights into the mechanical force response of cells to the external environment and may enhance our understanding of how the ECM regulates cell structure and function.
MICROSYSTEMS & NANOENGINEERING
(2023)
Article
Optics
Chuanbiao Bai, Zhaoxiang Jiang, Jiangcheng Zhao, Shangquan Wu, Qingchuan Zhang
Summary: This study develops a pixelated polarization-based parallel phase-shifting digital holographic microscopy method for the 3D dynamic observation of human sperm. The methodology allows for the retrieval of the 3D trajectory and motion parameters of sperm, and reconstructs the sperm head orientation and the thin, highly-dynamic flagellum. This system provides more comprehensive information on sperm motility and morphology, which is significant for male reproductive research.
Article
Nanoscience & Nanotechnology
Yao-Yao Bai, Bin Zhang, Xu-Ping Wu, Xue-Mei Luo, Guang-Ping Zhang
Summary: To address the trade-off between high sensitivity and wide sensing range, researchers developed a flexible pressure sensor with a mass-gradient distribution of Cu onto a textile coated with Ti3C2T x nanosheets. This sensor achieved both high sensitivity and wide sensing range by continuously changing the contact area and conductivity of the contact points under compressive loading. It also demonstrated excellent cycling stability, fast response/recovery time, and breathability, enabling wide applications in monitoring human physiological signals, transmitting encrypted information, and distinguishing pressure distribution in real time.
ACS APPLIED NANO MATERIALS
(2023)
Article
Engineering, Electrical & Electronic
Si-Qi Wang, Bin Zhang, Rong-Hao Qiao, Yan-Wen Luo, Xue-Mei Luo, Guang-Ping Zhang
Summary: Researchers have successfully fabricated a competitive reaction-driven MnO2 nanorod network on a nickel substrate, exhibiting high electroactivity and large strain. This material shows great potential in low-voltage electrochemical actuators for implantable medical devices.
ACS APPLIED ELECTRONIC MATERIALS
(2023)
Article
Chemistry, Physical
Yongpei Peng, Junhui Zhang, Weiwei Xue, Wenjie Wu, Yu Wang, Kainan Mei, Ye Chen, Depeng Rao, Tianhao Yan, Jianye Wang, Yunxia Cao, Shangquan Wu, Qingchuan Zhang
Summary: This study investigates oocytes from a mechanical perspective and characterizes their life activities through nanomechanical vibrations. The findings reveal significant nanomechanical vibrations in oocytes at different developmental stages, which are caused by the cytoskeleton and the distribution of mitochondria.
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
