DNA enzymes as potential therapeutics: towards clinical application of 10-23 DNAzymes
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Title
DNA enzymes as potential therapeutics: towards clinical application of 10-23 DNAzymes
Authors
Keywords
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Journal
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 15, Issue 5, Pages 689-711
Publisher
Informa Healthcare
Online
2015-03-14
DOI
10.1517/14712598.2015.1025048
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- Unknown
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