Syndecan-2 Attenuates Radiation-induced Pulmonary Fibrosis and Inhibits Fibroblast Activation by Regulating PI3K/Akt/ROCK Pathway via CD148

Molecular networks underlying myofibroblast fate and fibrosis

(2016) April Stempien-Otero et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Major apoptotic mechanisms and genes involved in apoptosis

(2016) Yağmur Kiraz et al.   TUMOR BIOLOGY

Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways

(2016) Julia Barbara Kral et al.   Scientific Reports

Effect of 2-arachidonoylglycerol on myosin light chain phosphorylation and platelet activation: The role of phosphatidylinositol 3 kinase/AKT pathway

(2014) Maria Grazia Signorello et al.   BIOCHIMIE

Pneumonitis and pulmonary fibrosis associated with breast cancer treatments

(2014) Claudia Omarini et al.   BREAST CANCER RESEARCH AND TREATMENT

Prostaglandin E2Inhibits α-Smooth Muscle Actin Transcription during Myofibroblast Differentiation via Distinct Mechanisms of Modulation of Serum Response Factor and Myocardin-related Transcription Factor-A

(2014) Loka R. K. Penke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shed syndecan-2 inhibits angiogenesis

(2014) G. De Rossi et al.   JOURNAL OF CELL SCIENCE

IPF Fibroblasts Are Desensitized to Type I Collagen Matrix-Induced Cell Death by Suppressing Low Autophagy via Aberrant Akt/mTOR Kinases

(2014) Richard Seonghun Nho et al.   PLoS One

Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation

(2013) Francesco Ortuso et al.   ACS Chemical Biology

Syndecan-2 Exerts Antifibrotic Effects by Promoting Caveolin-1–mediated Transforming Growth Factor-β Receptor I Internalization and Inhibiting Transforming Growth Factor-β1 Signaling

(2013) Yuanyuan Shi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Involvement of PI3K and ROCK signaling pathways in migration of bone marrow-derived mesenchymal stem cells through human brain microvascular endothelial cell monolayers

(2013) Mei-Na Lin et al.   BRAIN RESEARCH

Molecular Mechanisms and Treatment of Radiation-Induced Lung Fibrosis

(2013) Nian-Hua Ding et al.   CURRENT DRUG TARGETS

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

(2013) Yong Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Modulation of the Rho/ROCK Pathway in Heart and Lung after Thorax Irradiation Reveals Targets to Improve Normal Tissue Toxicity

(2012) Virginie Monceau et al.   CURRENT DRUG TARGETS

Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148

(2011) James R. Whiteford et al.   MOLECULAR BIOLOGY OF THE CELL

Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4

(2010) Dianhua Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of serum response factor in the pathogenesis of disease

(2010) Joseph M Miano   LABORATORY INVESTIGATION

Linking actin dynamics and gene transcription to drive cellular motile functions

(2010) Eric N. Olson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pathogenetic mechanisms in radiation fibrosis

(2010) John Yarnold et al.   RADIOTHERAPY AND ONCOLOGY

Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells

(2009) Jasminka Omerovic et al.   BIOCHEMICAL JOURNAL

Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines

(2009) K. Hayashida et al.   BLOOD

Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation

(2009) S. B. Haudek et al.   CARDIOVASCULAR RESEARCH

The tyrosine phosphatase CD148 interacts with the p85 regulatory subunit of phosphoinositide 3-kinase

(2008) Nobuo Tsuboi et al.   BIOCHEMICAL JOURNAL