NRF2 prevents hypertension, increased ADMA, microvascular oxidative stress, and dysfunction in mice with two weeks of ANG II infusion

An overview of the mechanisms and novel roles of Nrf2 in cardiovascular diseases

(2016) Shuai Jiang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Heme oxygenase-1 suppresses a pro-inflammatory phenotype in monocytes and determines endothelial function and arterial hypertension in mice and humans

(2015) Philip Wenzel et al.   EUROPEAN HEART JOURNAL

Thromboxane Prostanoid Receptors Enhance Contractions, Endothelin-1, and Oxidative Stress in Microvessels From Mice With Chronic Kidney Disease

(2015) C. Wang et al.   HYPERTENSION

Downregulation of Nuclear Factor Erythroid 2–Related Factor and Associated Antioxidant Genes Contributes to Redox-Sensitive Vascular Dysfunction in Hypertension

(2015) Rhéure A. Lopes et al.   HYPERTENSION

Activation of Nuclear Factor Erythroid 2-Related Factor 2 Coordinates Dimethylarginine Dimethylaminohydrolase/PPAR- /Endothelial Nitric Oxide Synthase Pathways That Enhance Nitric Oxide Generation in Human Glomerular Endothelial Cells

(2015) Z. Luo et al.   HYPERTENSION

Remodeling of Afferent Arterioles From Mice With Oxidative Stress Does Not Account for Increased Contractility but Does Limit Excessive Wall StressNovelty and Significance

(2015) Lingli Li et al.   HYPERTENSION

Reduced Renal Methylarginine Metabolism Protects against Progressive Kidney Damage

(2015) J. A. P. Tomlinson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Oxidative Stress in Hypertension: Role of the Kidney

(2013) Magali Araujo et al.   ANTIOXIDANTS & REDOX SIGNALING

Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease

(2013) Dick de Zeeuw et al.   NEW ENGLAND JOURNAL OF MEDICINE

Asymmetric Dimethylarginine and Reactive Oxygen Species

(2012) Christopher S. Wilcox   HYPERTENSION

Bardoxolone Methyl Decreases Megalin and Activates Nrf2 in the Kidney

(2012) S. A. Reisman et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Biology and Therapeutic Potential of the DDAH/ADMA Pathway

(2011) F. Arrigoni et al.   CURRENT PHARMACEUTICAL DESIGN

Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes

(2011) Pablo E. Pergola et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impaired Endothelial Function and Microvascular Asymmetrical Dimethylarginine in Angiotensin II–Infused Rats

(2010) Dan Wang et al.   HYPERTENSION

Effects of tempol and redox-cycling nitroxides in models of oxidative stress

(2010) Christopher S. Wilcox   PHARMACOLOGY & THERAPEUTICS

Cellular ADMA: Regulation and action

(2009) Tom Teerlink et al.   PHARMACOLOGICAL RESEARCH

Asymmetric dimethylarginine, oxidative stress, and vascular nitric oxide synthase in essential hypertension

(2008) Dan Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Global burden of blood-pressure-related disease, 2001

(2008) Carlene MM Lawes et al.   LANCET