Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures

Published 2018 View Full Article

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Title
Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures
Authors
Keywords
protein structure, genetic variation, spatial distribution, clustering, constraint, 3D model, evolution, ClinVar, COSMIC, gNOMAD
Journal
AMERICAN JOURNAL OF HUMAN GENETICS
Volume 102, Issue 3, Pages 415-426
Publisher
Elsevier BV
Online
2018-02-16
DOI
10.1016/j.ajhg.2018.01.017

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