Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms

Title
Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms
Authors
Keywords
induced pluripotent stem cells, IFT140, functional genomics, kidney organoid, cilia, nephronophthisis, CRISPR/Cas9, gene correction
Journal
AMERICAN JOURNAL OF HUMAN GENETICS
Volume 102, Issue 5, Pages 816-831
Publisher
Elsevier BV
Online
2018-04-26
DOI
10.1016/j.ajhg.2018.03.014

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