17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use

Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium

(2017) Niloufar Farzan et al.   PHARMACOGENOMICS

17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells

(2016) Benjamin Joachim Schmiedel et al.   Nature Communications

Childhood asthma is associated with mutations and gene expression differences ofORMDLgenes that can interact

(2015) A. A. Toncheva et al.   ALLERGY

Differences in asthma genetics between Chinese and other populations

(2013) Ting F. Leung et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma

(2012) V Berce et al.   PHARMACOGENOMICS JOURNAL

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chromosome 17q21 Gene Variants Are Associated with Asthma and Exacerbations but Not Atopy in Early Childhood

(2008) Hans Bisgaard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications

(2008) Roger Tavendale et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY