Global remodeling of the mouse DNA methylome during aging and in response to calorie restriction

Caloric restriction delays age-related methylation drift

(2017) Shinji Maegawa et al.   Nature Communications

Comparative idiosyncrasies in life extension by reduced mTOR signalling and its distinctiveness from dietary restriction

(2016) Michael Garratt et al.   AGING CELL

Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes

(2016) Vadim N. Gladyshev   AGING CELL

Reference-free deconvolution of DNA methylation data and mediation by cell composition effects

(2016) E. Andres Houseman et al.   BMC BIOINFORMATICS

DNA methylation and healthy human aging

(2015) Meaghan J. Jones et al.   AGING CELL

Base resolution methylome profiling: considerations in platform selection, data preprocessing and analysis

(2015) Zhifu Sun et al.   Epigenomics

Protein Oxidation and Proteolytic Signalling in Aging

(2014) Christiane Ott et al.   CURRENT PHARMACEUTICAL DESIGN

Dietary restriction of rodents decreases aging rate without affecting initial mortality rate - a meta-analysis

(2013) Mirre J. P. Simons et al.   AGING CELL

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

(2013) David E. Harrison et al.   AGING CELL

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects

(2013) Joseph L. McClay et al.   HUMAN MOLECULAR GENETICS

Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites

(2013) I. Florath et al.   HUMAN MOLECULAR GENETICS

Expression of DNA Methyltransferases Is Influenced by Growth Hormone in the Long-Living Ames Dwarf Mouse In Vivo and In Vitro

(2013) V. L. Armstrong et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Continuous Aging of the Human DNA Methylome Throughout the Human Lifespan

(2013) Åsa Johansson et al.   PLoS One

Aging epigenetics: Causes and consequences

(2012) Covadonga Huidobro et al.   MOLECULAR ASPECTS OF MEDICINE

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Aging effects on DNA methylation modules in human brain and blood tissue

(2012) Steve Horvath et al.   GENOME BIOLOGY

How epigenetics can explain human metastasis: A new role for microRNAs

(2011) Amaia Lujambio et al.   CELL CYCLE

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

(2010) V. K. Rakyan et al.   GENOME RESEARCH

Widespread and tissue specific age-related DNA methylation changes in mice

(2010) S. Maegawa et al.   GENOME RESEARCH

Comparison of the DNA methylation profiles of human peripheral blood cells and transformed B-lymphocytes

(2010) Yan V. Sun et al.   HUMAN GENETICS

CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer

(2010) A Lujambio et al.   ONCOGENE

Aging of signal transduction pathways, and pathology

(2008) Morgan E. Carlson et al.   EXPERIMENTAL CELL RESEARCH