Targeting glucosylceramide synthase induction of cell surface globotriaosylceramide (Gb3) in acquired cisplatin-resistance of lung cancer and malignant pleural mesothelioma cells

Title
Targeting glucosylceramide synthase induction of cell surface globotriaosylceramide (Gb3) in acquired cisplatin-resistance of lung cancer and malignant pleural mesothelioma cells
Authors
Keywords
Cisplatin, Glucosylceramide synthase (GCS), Globotriaosylceramide (Gb3), Lung cancer, Multidrug resistance 1/P-glycoprotein (MDR1), Multidrug resistance-associated protein 1 (MRP1), Malignant pleural mesothelioma (MPM), DL-threo-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol (PPMP), Cyclosporin A, Acquired drug resistance
Journal
EXPERIMENTAL CELL RESEARCH
Volume 336, Issue 1, Pages 23-32
Publisher
Elsevier BV
Online
2015-05-23
DOI
10.1016/j.yexcr.2015.05.012

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