Perivascular adipose tissue dysfunction aggravates adventitial remodeling in obese mini pigs via NLRP3 inflammasome/IL-1 signaling pathway

MD2 Blockage Protects Obesity-Induced Vascular Remodeling via Activating AMPK/Nrf2

(2017) Lintao Wang et al.   Obesity

Teneligliptin, a dipeptidyl peptidase-4 inhibitor, attenuated pro-inflammatory phenotype of perivascular adipose tissue and inhibited atherogenesis in normoglycemic apolipoprotein-E-deficient mice

(2017) Hotimah Masdan Salim et al.   VASCULAR PHARMACOLOGY

Vitamin D Deficiency Accelerates Coronary Artery Disease Progression in SwineHighlights

(2016) Songcang Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Obesity-Related Perivascular Adipose Tissue Damage Is Reversed by Sustained Weight Loss in the RatHighlights

(2016) Charlotte E. Bussey et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Clinical Perspective: Contribution of Dysfunctional Perivascular Adipose Tissue (PVAT) to Cardiovascular Risk

(2016) Xiaoming Lian et al.   CURRENT HYPERTENSION REPORTS

Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes

(2016) Kashyap A. Patel et al.   DIABETES

Early adventitial activation characterized by NADPH oxidase expression and neovascularization in an aortic transplantation model

(2016) Mengyao Sun et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Effect of long-term treatment with melatonin on vascular markers of oxidative stress/inflammation and on the anticontractile activity of perivascular fat in aging mice

(2016) Claudia Agabiti-Rosei et al.   HYPERTENSION RESEARCH

The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation

(2016) Deepika Sharma et al.   JOURNAL OF CELL BIOLOGY

Obesity Severity and Duration Are Associated With Incident Metabolic Syndrome: Evidence Against Metabolically Healthy Obesity From the Multi-Ethnic Study of Atherosclerosis

(2016) Morgana Mongraw-Chaffin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats

(2016) Ernesto Martínez-Martínez et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Vitamin D controls resistance artery function through regulation of perivascular adipose tissue hypoxia and inflammation

(2016) Christopher J. Pelham et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Macrophages activate iNOS signaling in adventitial fibroblasts and contribute to adventitia fibrosis

(2016) Guannan Zhang et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells

(2016) Megan M. Robblee et al.   Cell Reports

Complement-Mediated Macrophage Polarization in Perivascular Adipose Tissue Contributes to Vascular Injury in Deoxycorticosterone Acetate–Salt MiceSignificance

(2015) Cheng-Chao Ruan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lean and Obese Coronary Perivascular Adipose Tissue Impairs Vasodilation via Differential Inhibition of Vascular Smooth Muscle K+ Channels

(2015) J. N. Noblet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vitamin D Protects Against Atherosclerosis via Regulation of Cholesterol Efflux and Macrophage Polarization in Hypercholesterolemic SwineSignificance

(2015) Kai Yin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

(2015) Jong-Seok Moon et al.   JOURNAL OF CLINICAL INVESTIGATION

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

(2015) Hexin Shi et al.   NATURE IMMUNOLOGY

Perivascular Adipose Tissue in Vascular Function and Disease

(2014) Nicholas K. Brown et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Reducing RIP140 Expression in Macrophage Alters ATM Infiltration, Facilitates White Adipose Tissue Browning, and Prevents High-Fat Diet-Induced Insulin Resistance

(2014) P.-S. Liu et al.   DIABETES

Perivascular Adipose Tissue Potentiates Contraction of Coronary Vascular Smooth Muscle

(2013) Meredith Kohr Owen et al.   CIRCULATION

Apolipoprotein AI and High-Density Lipoprotein Have Anti-Inflammatory Effects on Adipocytes via Cholesterol Transporters

(2013) Tomio Umemoto et al.   CIRCULATION RESEARCH

The complex P2X7receptor/inflammasome in perivascular fat tissue of heavy smokers

(2013) Chiara Rossi et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Perivascular Adipose Tissue–Derived Complement 3 Is Required for Adventitial Fibroblast Functions and Adventitial Remodeling in Deoxycorticosterone Acetate–Salt Hypertensive Rats

(2010) Cheng-Chao Ruan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Epicardial Perivascular Adipose-Derived Leptin Exacerbates Coronary Endothelial Dysfunction in Metabolic Syndrome via a Protein Kinase C-β Pathway

(2010) Gregory A. Payne et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Obesity Promotes Inflammation in Periaortic Adipose Tissue and Angiotensin II-Induced Abdominal Aortic Aneurysm Formation

(2009) Sara B. Police et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proinflammatory Phenotype of Perivascular Adipocytes

(2009) Tapan K. Chatterjee et al.   CIRCULATION RESEARCH