Novel insights into the regulation of miRNA transcriptional control: implications for T2D and related complications

Regulation of Vascular Smooth Muscle Cell Dysfunction Under Diabetic Conditions by miR-504Significance

(2016) Marpadga A. Reddy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Identification of microRNAs regulating Hlxb9 gene expression during the induction of insulin-producing cells

(2016) Changzheng Mu et al.   CELL BIOLOGY INTERNATIONAL

Differential DNA methylation of microRNAs within promoters, intergenic and intragenic regions of type 2 diabetic, pre-diabetic and non-diabetic individuals

(2016) Carmen Pheiffer et al.   CLINICAL BIOCHEMISTRY

miR-696 plays a role in hepatic gluconeogenesis in ob/ob mice by targeting PGC-1α

(2016) Zhijuan Fang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Integrator of Stress Responses Calmodulin Binding Transcription Activator 1 (Camta1) Regulates miR-212/miR-132 Expression and Insulin Secretion

(2016) Inês Guerra Mollet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional regulation of the miR-212/miR-132 cluster in insulin-secreting β-cells by cAMP-regulated transcriptional co-activator 1 and salt-inducible kinases

(2016) Helena Anna Malm et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy

(2016) Shawn S. Badal et al.   Nature Communications

miRNA let-7 expression is regulated by glucose and TNF-  by a remote upstream promoter

(2015) M. Katayama et al.   BIOCHEMICAL JOURNAL

Identification of microRNA biomarkers in type 2 diabetes: a meta-analysis of controlled profiling studies

(2015) Hongmei Zhu et al.   DIABETOLOGIA

Promoter hypermethylation of let-7a-3 is relevant to its down-expression in diabetic nephropathy by targeting UHRF1

(2015) Rui Peng et al.   GENE

p75NTR-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte–endothelial crosstalk in diabetes after limb ischaemia

(2015) Andrea Caporali et al.   Nature Communications

miR-24 in diabetes

(2015) Yaozu Xiang   Oncotarget

Oscillating glucose and constant high glucose induce endoglin expression in endothelial cells: the role of oxidative stress

(2014) Lucia La Sala et al.   ACTA DIABETOLOGICA

NFkappaB activation is essential for miR-21 induction by TGFβ1 in high glucose conditions

(2014) Radha Madhyastha et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Epigenetic Regulation of the DLK1-MEG3 MicroRNA Cluster in Human Type 2 Diabetic Islets

(2014) Vasumathi Kameswaran et al.   Cell Metabolism

Serum MiRNA Biomarkers serve as a Fingerprint for Proliferative Diabetic Retinopathy

(2014) Shao Qing et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes

(2014) E. Nilsson et al.   DIABETES

Global DNA methylation as a possible biomarker for diabetic retinopathy

(2014) Zhila Maghbooli et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Identification of a splicing variant that regulates type 2 diabetes risk factor CDKAL1 level by a coding-independent mechanism in human

(2014) B. Zhou et al.   HUMAN MOLECULAR GENETICS

DNA methylation and body-mass index: a genome-wide analysis

(2014) Katherine J Dick et al.   LANCET

Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome

(2014) Lily Agranat-Tamir et al.   NUCLEIC ACIDS RESEARCH

Differential Methylation of TCF7L2 Promoter in Peripheral Blood DNA in Newly Diagnosed, Drug-Naïve Patients with Type 2 Diabetes

(2014) Silvia Canivell et al.   PLoS One

DNA methylation of microRNA-375 in impaired glucose tolerance

(2014) XIAOLI WANG et al.   Experimental and Therapeutic Medicine

Drosha Promotes Splicing of a Pre-microRNA-like Alternative Exon

(2014) Mallory A. Havens et al.   PLoS Genetics

Ethnic Differences in MicroRNA-375 Expression Level and DNA Methylation Status in Type 2 Diabetes of Han and Kazak Populations

(2014) Xiangyun Chang et al.   Journal of Diabetes Research

Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study

(2013) B. Hidalgo et al.   DIABETES

MicroRNA-106b induces mitochondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2

(2013) Ying Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Alternative Splicing Regulates Biogenesis of miRNAs Located across Exon-Intron Junctions

(2013) Ze’ev Melamed et al.   MOLECULAR CELL

Expression and DNA methylation status of microRNA-375 in patients with type 2 diabetes mellitus

(2013) KAN SUN et al.   Molecular Medicine Reports

Biogenesis of intronic miRNAs located in clusters by independent transcription and alternative splicing

(2013) P. Ramalingam et al.   RNA

PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs

(2013) Annalisa Marsico et al.   GENOME BIOLOGY

A novel source for miR-21 expression through the alternative polyadenylation of VMP1 gene transcripts

(2012) Judit Ribas et al.   NUCLEIC ACIDS RESEARCH

Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs

(2012) X Li et al.   ONCOGENE

The emerging challenge in diabetes: The “metabolic memory”

(2012) Antonio Ceriello   VASCULAR PHARMACOLOGY

Effect of CpG Island Methylation on MicroRNA Expression in the k-562 Cell Line

(2011) Yang Yang et al.   BIOCHEMICAL GENETICS

Epigenetics in Alternative Pre-mRNA Splicing

(2011) Reini F. Luco et al.   CELL

Expression of the Splicing Factor Gene SFRS10 Is Reduced in Human Obesity and Contributes to Enhanced Lipogenesis

(2011) Jussi Pihlajamäki et al.   Cell Metabolism

Epigenetic Changes in Mitochondrial Superoxide Dismutase in the Retina and the Development of Diabetic Retinopathy

(2011) Q. Zhong et al.   DIABETES

DNA methylation in white blood cells

(2011) Mary Beth Terry et al.   Epigenetics

Identifying transcriptional start sites of human microRNAs based on high-throughput sequencing data

(2011) Chia-Hung Chien et al.   NUCLEIC ACIDS RESEARCH

IL-2R common  -chain is epigenetically silenced by nucleophosphin-anaplastic lymphoma kinase (NPM-ALK) and acts as a tumor suppressor by targeting NPM-ALK

(2011) Q. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-21 targets peroxisome proliferators-activated receptor-  in an autoregulatory loop to modulate flow-induced endothelial inflammation

(2011) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation and function of miRNA-21 in health and disease

(2011) Regalla Kumarswamy et al.   RNA Biology

Feed-Forward Microprocessing and Splicing Activities at a MicroRNA–Containing Intron

(2011) Maja M. Janas et al.   PLoS Genetics

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

(2010) Christopher G Bell et al.   BMC Medical Genomics

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

DNA Methylation Mediated by a MicroRNA Pathway

(2010) Liang Wu et al.   MOLECULAR CELL

Genomics, Type 2 Diabetes, and Obesity

(2010) Mark I. McCarthy   NEW ENGLAND JOURNAL OF MEDICINE

Structure and activity of putative intronic miRNA promoters

(2010) A. M. Monteys et al.   RNA

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

A transcription factor affinity-based code for mammalian transcription initiation

(2009) M. Megraw et al.   GENOME RESEARCH

Functional Association of the Microprocessor Complex with the Spliceosome

(2009) N. Kataoka et al.   MOLECULAR AND CELLULAR BIOLOGY

Epigenetic mechanisms that underpin metabolic and cardiovascular diseases

(2009) Peter D. Gluckman et al.   Nature Reviews Endocrinology

Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

(2008) Alexander Marson et al.   CELL

Alterations in MicroRNA Expression Contribute to Fatty Acid-Induced Pancreatic  -Cell Dysfunction

(2008) P. Lovis et al.   DIABETES

Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

(2008) C. Ling et al.   DIABETOLOGIA

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

MicroRNA-directed transcriptional gene silencing in mammalian cells

(2008) D. H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-373 induces expression of genes with complementary promoter sequences

(2008) R. F. Place et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA