Downregulation of Drp1, a fission regulator, is associated with human lung and colon cancers

Drp1-Dependent Mitochondrial Fission Plays Critical Roles in Physiological and Pathological Progresses in Mammals

(2017) Chenxia Hu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

(2016) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson’s disease model induced by MPTP

(2016) Emily Filichia et al.   Scientific Reports

Mitochondrial dynamics and mitochondrial quality control

(2015) Hong-Min Ni et al.   Redox Biology

Drp1 in Ischemic Neuronal Death: An Unusual Suspect

(2014) H. Pradeep et al.   CURRENT MEDICINAL CHEMISTRY

In vivo functions of Drp1: Lessons learned from yeast genetics and mouse knockouts

(2013) Hiromi Sesaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Drp1 is dispensable for apoptotic cytochromecrelease in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes

(2013) P Clerc et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

(2013) Stephen L. Archer   NEW ENGLAND JOURNAL OF MEDICINE

Depletion of mitochondrial fission factor DRP1 causes increased apoptosis in human colon cancer cells

(2012) Akane Inoue-Yamauchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of Med1/TRAP220 promotes the invasion and metastasis of human non-small-cell lung cancer cells by modulating the expression of metastasis-related genes

(2012) Hyun-Ju Kim et al.   CANCER LETTERS

Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

(2012) Jalees Rehman et al.   FASEB JOURNAL

Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress

(2012) W. Qian et al.   JOURNAL OF CELL SCIENCE

Dynamin, a membrane-remodelling GTPase

(2012) Shawn M. Ferguson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial dynamics regulates migration and invasion of breast cancer cells

(2012) J Zhao et al.   ONCOGENE

Mitochondrial dynamics in neurodegeneration

(2012) Kie Itoh et al.   TRENDS IN CELL BIOLOGY

Gender Differences in Cancer Susceptibility: An Inadequately Addressed Issue

(2012) M. Tevfik Dorak et al.   Frontiers in Genetics

Dynamin: Functional Design of a Membrane Fission Catalyst

(2011) Sandra L. Schmid et al.   Annual Review of Cell and Developmental Biology

Mitochondria as a Therapeutic Target for Aging and Neurodegenerative Diseases

(2011) P. H. Reddy et al.   Current Alzheimer Research

Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

(2010) Chuang-Rung Chang et al.   Annals of the New York Academy of Sciences

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

(2009) Junko Wakabayashi et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

(2009) Naotada Ishihara et al.   NATURE CELL BIOLOGY

Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA

(2008) Philippe A. Parone et al.   PLoS One

Mitochondrial dynamics and cancer

(2008) Stéphanie Grandemange et al.   SEMINARS IN CANCER BIOLOGY