Article
Chemistry, Multidisciplinary
Chaoyu Fan, Yonghua Tang, Hao Wang, Yifan Huang, Fei Xu, Yun Yang, Yangyang Huang, Weifeng Rong, Youhui Lin
Summary: Inspired by the structures of enzymes, researchers have developed a fast and robust method to generate ZIF-90 metallo-nanozymes. ZIF-90 exhibits enzyme-like activity, high stability, and recyclability.
Article
Chemistry, Multidisciplinary
Rajib Moi, Moumita Chandra, Kartik Maity, Debabrata Pradhan, Kumar Biradha
Summary: Coordination polymers and metal-organic frameworks have shown promise as photocatalytic materials for hydrogen evolution reaction. This study reported two isostructural fluorescein-based coordination polymers as efficient photocatalysts under white light. The band gap of the polymers was found to have a significant effect on their photocatalytic efficiency, with Mn-FCB exhibiting higher activity due to extended visible light absorption and lower band gap.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Chemistry, Analytical
Xu Zhu, Jing Tang, Xilian Ouyang, Yibo Liao, Haopeng Feng, Jiangfang Yu, Li Chen, Yating Lu, Yuyang Yi, Lin Tang
Summary: In this study, a portable paper-based colorimetric sensor with a smartphone platform was developed for on-site and quantitative analysis of antibiotic residues. The method is based on aptamer-regulated nanozyme activity and shows an ultrahigh sensitivity. This analysis platform has excellent potential for on-site and mass screening of antibiotic residues.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Rong-Jia Wei, Mo Xie, Ri-Qin Xia, Jun Chen, Hua-Juan Hu, Guo-Hong Ning, Dan Li
Summary: This article presents a method for the rapid and scalable construction of Au-MOFs at ambient conditions, demonstrating their high chemical stability under alkaline conditions and good performance as heterogeneous catalysts.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Nanoscience & Nanotechnology
Joseph F. Olorunyomi, Jacinta F. White, Thomas R. Gengenbach, Rachel A. Caruso, Cara M. Doherty
Summary: A bioinspired metal-organic framework (MOF) material has been developed to achieve high sensitivity and selectivity for Pb2+ through fluorescence sensing by imitating metal-protein interactions. The HS-C/Au(x)/UiO-66 composite films, modified with both gold nanoparticles and thiol-functionalized carbon dots, demonstrate extraordinary sensitivity to Pb2+ and can switch between fluorescence quenching and enhancement by adjusting the Au content. This solid-state sensing platform shows great potential for ensuring public safety from Pb2+ contamination in drinking water.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Biomaterials
Ning Nie, Yifan Liu, Bing Li, Zhentao Hua, Jianfeng Liu, Jinjian Liu, Wei Wang
Summary: The copper phosphate nanospheres coated by poly (ethylene glycol) diacrylate (Cu-3(PO4)(2)@PEGDA) act as nanozymes to enhance the anti-tumor effects of oxidative stress therapy (OST) by catalyzing the generation of hydroxyl radicals and consuming glutathione. The photothermal properties of Cu-3(PO4)(2)@PEGDA further improve the outcome of the therapy, and a new PEGylation strategy for peroxidase-like nanozymes is proposed to overcome traditional drawbacks.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Engineering, Environmental
Weian Wang, Dalei Wang, Haizeng Song, Derek Hao, Bentuo Xu, Jiawei Ren, Mingliang Wang, Chaoqing Dai, Yueyue Wang, Wei Liu
Summary: This study investigates the photocatalytic activity of Au@ZIF-Co/Zn for treating Rhodamine B/Cr(VI) mixture solutions and 4-nitrophenol solution under visible light. It is found that the size of gold nanoparticles significantly affects the surface plasmon resonance effect, internal electron transfer capacity, and carrier density change. The charge-transfer photocatalytic mechanism and size influence of gold nanoparticles in composite photocatalysts are revealed through photoelectric chemistry experiments and radical quenching experiments.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Peng Wu, Yu Shen, Hongfeng Li, Wenxiong Shi, Lulu Zhang, Ting Pan, Wenbo Pei, Weina Zhang, Fengwei Huo
Summary: Metal nanoparticles supported on metal-organic frameworks have shown excellent performance in catalytic reactions. By controlling the growth behavior of nanoparticles on specific binding sites of MOFs, improved reaction performance can be achieved, providing insights into the structure-activity relationship.
Article
Chemistry, Analytical
Hong-Yan Shan, Ke-Yi Shen, Shu-Shu Song, Can Chen, Fei-Ying Ruan, Ai-Jun Wang, Pei-Xin Yuan, Jiu-Ju Feng
Summary: Autism spectrum disorders (ASDs) are a significant concern worldwide, and miRNA detection using the photoelectrochemical (PEC) method has attracted attention. In this research, 1,2,4,5-benzenetetramine tetrahydrochloride (BTA) was used as a ligand to form AuCl4- -MOFs, followed by the formation of Au NPs embedded in MOFs (MOFs@Au NPs). The MOFs@Au NPs showed significantly increased anode photocurrent compared to Au NPs alone. A label-free PEC biosensor was constructed using MOFs@Au NPs as a photosensitizer to detect miRNA-23a-3p related to ASDs. The sensor exhibited a wide linear range and low limit of detection, making it promising for blood-based RNA detection in biomedicine.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Inorganic & Nuclear
Tong Li, Xuanying Hu, Cui Yang, Lei Han, Kai Tao
Summary: By constructing a ZnCoS@NiMn-LDH heterostructure with a built-in electric field, outstanding energy storage properties have been achieved for the electrode material. This research provides a new approach for designing high-performance electrode materials through heterostructure and morphology engineering.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Stamatis S. Passadis, Sofia Hadjithoma, Michael G. Papanikolaou, Anastasios D. Keramidas, Haralampos N. Miras, Themistoklis A. Kabanos
Summary: The hydrolytically stable dioxime ligand, H(3)pidiox, exhibits strong chelation with hard metals in high oxidation states, potentially useful in metal sequestering processes from aqueous solutions. Experimental data analysis indicates that zirconium compounds with different structural features can be synthesized under different pH conditions.
DALTON TRANSACTIONS
(2022)
Article
Materials Science, Biomaterials
Zhengzou Fang, Erli Yang, Ying Du, Daqing Gao, Guoqiu Wu, Yuanjian Zhang, Yanfei Shen
Summary: Developing a nanoplatform that combines graphene oxide, metal-organic framework, and folate-functionalized erythrocyte membrane is important for improving cancer therapy outcomes. This nanoplatform can precisely target cancer cells, avoid immune elimination, and have robust imaging capabilities. It can also trigger synergistic photothermal and photodynamic therapy, promoting the generation of tumor-associated antigens and an anti-tumor immune response. This innovative biomimetic nanoplatform opens up new possibilities for cancer diagnosis and therapy.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Review
Chemistry, Physical
Jun Guo, Yue Wan, Yanfei Zhu, Meiting Zhao, Zhiyong Tang
Summary: MNP/MOF composite photocatalysts exhibit excellent performance and great potential applications, especially in photocatalytic hydrogen production, carbon dioxide reduction, organic transformation reactions, and photodegradation of pollutants. The challenges and prospects in the current research are also proposed and discussed for further advancement in this hot research field.
Article
Chemistry, Multidisciplinary
Peipei Yang, Jia Tao, Fengfeng Chen, Yuying Chen, Jiaqi He, Kui Shen, Peng Zhao, Yingwei Li
Summary: Nanozyme-based chemodynamic therapy (CDT) has emerged as an effective cancer treatment with low side effects and without the requirement of exogenous energy. Constructing a single kind of catalyst with multiple functions for enhanced CDT is still a challenge, but this study successfully synthesized seven types of bimetallic nanoparticles using a metal-organic framework, showing promising activity.
Article
Engineering, Environmental
Elham Ragheb, Mojtaba Shamsipur, Fahimeh Jalali, Farimah Mousavi
Summary: A novel adsorbent was prepared for the fast and selective removal of heavy metal ions Hg(II), Cd(II), and Pb(II). The adsorbent was made by immobilizing tripeptide glutathione on the surface of a magnetic metal-organic framework (Fe3O4-ZrMOF). The adsorbent showed a high adsorption capacity and efficiency, removing 95-99% of the target ions within 20 minutes.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Astronomy & Astrophysics
Guoying Zhao, Zhaosheng Li, Yuanyue Pan, Maurizio Falanga, Long Ji, Yupeng Chen, Shu Zhang
Summary: Type I X-ray bursts are the result of unstable thermonuclear burning on the surface of a neutron star, resulting in the release of energetic X-ray photons. These bursts interact with the surrounding accretion disk, increasing the accretion rate. By analyzing two photospheric radius expansion bursts in 4U 1636-536, it was found that the spectral fitting can be improved by considering enhanced persistent emission or reflection from the accretion disk. Evidence suggests that both Poynting-Robertson drag and disk reflection occurred during these bursts, and the disk reflection may contribute up to 20-30% of the total burst emissions.
ASTRONOMY & ASTROPHYSICS
(2022)
Article
Astronomy & Astrophysics
Xiaobo Li, Mingyu Ge, Lin Lin, Shuang-Nan Zhang, Liming Song, Xuelei Cao, Bing Zhang, Fangjun Lu, Yupeng Xu, Shaolin Xiong, Youli Tuo, Ying Tan, Weichun Jiang, Jinlu Qu, Shu Zhang, Lingjun Wang, Jieshuang Wang, Binbin Zhang, Peng Zhang, Chengkui Li, Congzhan Liu, Tipei Li, Qingcui Bu, Ce Cai, Yong Chen, Yupeng Chen, Zhi Chang, Li Chen, Tianxiang Chen, Yibao Chen, Weiwei Cui, Yuanyuan Du, Guanhua Gao, He Gao, Yudong Gu, Ju Guan, Chengcheng Guo, Dawei Han, Yue Huang, Jia Huo, Shumei Jia, Jing Jin, Lingda Kong, Bing Li, Gang Li, Wei Li, Xian Li, Xufang Li, Zhengwei Li, Xiaohua Liang, Jinyuan Liao, Hexin Liu, Hongwei Liu, Xiaojing Liu, Xuefeng Lu, Qi Luo, Tao Luo, Binyuan Ma, Ruican Ma, Xiang Ma, Bin Meng, Yi Nang, Jianyin Nie, Ge Ou, Xiaoqin Ren, Na Sai, Xinying Song, Liang Sun, Lian Tao, Chen Wang, Pengju Wang, Wenshuai Wang, Yusa Wang, Xiangyang Wen, Bobing Wu, Baiyang Wu, Mei Wu, Shuo Xiao, Sheng Yang, Yanji Yang, Qibin Yi, Qianqing Yin, Yuan You, Wei Yu, Fan Zhang, Hongmei Zhang, Juan Zhang, Wanchang Zhang, Wei Zhang, Yifei Zhang, Yuanhang Zhang, Haisheng Zhao, Xiaofan Zhao, Shijie Zheng, Dengke Zhou
Summary: This study reports the detection of a strong quasi-periodic oscillation (QPO) of about 40 Hz in an X-ray burst from the magnetar SGR J1935+2154, which is associated with FRB 200428. The discovery suggests that some FRBs may be related to strong oscillation processes of neutron stars, providing important clues for understanding the origin and mechanism of FRBs.
ASTROPHYSICAL JOURNAL
(2022)
Review
Multidisciplinary Sciences
Maonan Wang, Hui Jiang, Xiaohui Liu, Xuemei Wang
Summary: This study provides a brief overview of recent advances and challenges in the biophysical factors and strategies of tumor immune escape, and comprehensive analysis of the forces acting on tumor cells during immune escape. The development of biophysics is also dependent on the advancement of detection tools.
Article
Nanoscience & Nanotechnology
Yihan Wang, Ke Huang, Zhaojian Qin, Jiayu Zeng, Ying Zhang, Lihong Yin, Xiaohui Liu, Hui Jiang, Xuemei Wang
Summary: With the deepening of cancer clinical research, miRNAs provide new ideas for molecular diagnosis and treatment of tumors. Improving the molecular delivery efficiency of miRNA is the key to the success of miRNA therapy. The study proposes a self-assembly diagnosis and treatment technology based on metal precursor-mediated tumor microenvironmental response, which can achieve accurate targeting and cargo delivery.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biochemical Research Methods
Weiwei Liu, Farouk Semcheddine, Hui Jiang, Xuemei Wang
Summary: In this study, a multifunctional nanocomposite was successfully synthesized, which could efficiently load an anticancer drug and had excellent cell imaging and photothermal functions. After modification with folic acid, the composite material could target tumor cells and showed a highly effective inhibitory effect against various tumor cells through a chemo-photothermal synergistic effect.
BIOCONJUGATE CHEMISTRY
(2022)
Article
Engineering, Environmental
Tanziela Tanziela, Sana Shaikh, Fawad Ur Rehman, Farouk Semcheddine, Hui Jiang, Zuhong Lu, Xuemei Wang
Summary: Drug resistance is a major obstacle in cancer therapy. The emerging field of nanotechnology and exosomes as drug carriers offer promising strategies for effective and targeted delivery of therapeutic cargo to malignant sites. This study developed a bioresponsive self-assembly drug delivery platform using exosomes isolated from glioblastoma cells, which showed high cancer targeting and biocompatibility. These engineered exosomes can be used for early cancer diagnosis and have potential for targeted chemotherapy.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Maonan Wang, Zengchao Guo, Jiayu Zeng, Liu Liu, Yihan Wang, Jinpeng Wang, Hongbing Lu, Haijun Zhang, Hui Jiang, Xuemei Wang
Summary: This study found that KRAS is highly expressed in pancreatic cancer tumors and is closely related to poor patient prognosis. A smart bio-responsive nanomedicine was proposed to target-deliver KRAS shRNA and achieve cancer cell diagnosis and treatment through a special oxidative stress-responsive effect.
CHINESE CHEMICAL LETTERS
(2023)
Article
Engineering, Environmental
Zengchao Guo, Jiang Xiao, Weiwei Liu, Yihan Wang, Tengfei Liu, Hui Jiang, Xiaohui Liu, Xuemei Wang
Summary: Researchers have developed a multimode and broad-spectrum antimicrobial system based on cationic polypeptides and in situ self-assembled strategy. This system can effectively kill bacteria under irradiation and demonstrates high biocompatibility.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Hao Liu, Zhiming Liu, Yihan Wang, Jiang Xiao, Xiaohui Liu, Hui Jiang, Xuemei Wang
Summary: The biomineralization of tunable gold nanocrystals with in situ protein coronas by intracellular liquid-liquid phase separation (LLPS) was achieved for in situ molecule surface-enhanced Raman spectrum (SERS) analysis and tumor fluorescence identification. Anisotropic gold nanocrystals were obtained by regulating LLPS, allowing for directional growth and differentiation of clinical tumor tissue samples. This study reveals the mechanism of intracellular tunable nanocrystal biomineralization and provides the basis for its biomedical application.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Analytical
Jinpeng Wang, Qingxiu Xia, Ke Huang, Lihong Yin, Hui Jiang, Xiaohui Liu, Xuemei Wang
Summary: In this study, an ultrafast, specific, and accurate cancer cell imaging strategy based on dynamically self-assembling fluorescent nanoclusters was developed. It can rapidly and accurately distinguish lung cancer cells from normal cells within 1 minute, and has been validated in alveolar lavage fluid samples from lung cancer patients. This strategy provides a safe and promising cancer diagnostic platform for cancer therapy.
Article
Engineering, Environmental
Yi Han Wang, Ke Huang, Zhao Jian Qin, Hong Jie Xiong, Teng Fei Liu, Ting Ya Wang, Xiang Dong Lai, Xiao Hui Liu, Hui Jiang, Xue Mei Wang
Summary: In this study, a unique cancer microenvironment responsive bioreactor was constructed to form fluorescent and magnetic nanocomposites of the Au&Fe3O4-DNA complexes in situ. The Au&Fe3O4-DNA complexes efficiently inhibited tumor growth by consuming intracellular glutathione, inducing oxidative stress injury and activating apoptosis. Moreover, this system allowed enhanced photothermal therapy under near-infrared light irradiation, providing a promising approach for cancer early diagnosis and efficient treatment.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Chemistry, Analytical
Xinyi Xu, Xuemei Wang, Hui Jiang
Summary: This review focuses on the promoting effect of biosensing technology on the diagnosis and treatment of diabetes mellitus. The types of diabetes and their corresponding pathogeneses are introduced, followed by the diabetes prevalence and research progress at home and abroad. Breakthrough technology based on biosensing technology in the field of diabetes diagnosis and treatment is summarized. Diversified ways of blood glucose detection and multiple combinations of diabetes biomarkers are discussed for diagnosis, while various insulin administration routes and non-drug treatment means are presented for treatment. The prospect of the future development of diabetes diagnosis and treatment is put forward at the end of the review.
Review
Chemistry, Multidisciplinary
Hongjie Xiong, Liu Liu, Xiaohui Liu, Hui Jiang, Xuemei Wang
Summary: Aptamers have excellent molecule-targeting ability and are promising candidates for cancer immunotherapy due to their advantages over monoclonal antibodies. By combining tumor- and immune cell-targeting aptamers, multivalent bispecific aptamers were designed to enhance immune efficacy. Aptamers can also be combined with nanomaterials and immune cells, showing potential in targeted cargo delivery, regulation of cell-cell interactions, and tumor immunogenicity activation.
CHEMISTRY-SWITZERLAND
(2023)
Article
Materials Science, Multidisciplinary
Haiming Gao, Zhaojian Qin, Yihan Wang, Hongjie Xiong, Xuemei Wang, Hui Jiang
Summary: This study demonstrates the role of hydroxypropyl-fl-cyclodextrin (HP -fl-CD) in directing the self-assembly of dipeptide-protected gold nano-clusters (Ac-CG-Au NCs) into 1-D assemblies. The resulting assemblies exhibit enhanced stability and higher charge transfer efficiency, leading to a 2-fold larger photoluminescence quantum yield compared to Ac-CG-Au NCs. The pH-sensitive emission of the 1-D assemblies makes them suitable for selective labeling of lysosomes in HeLa cells, providing a potential tool for subcellular trafficking observation.
ACS MATERIALS LETTERS
(2022)
Review
Engineering, Biomedical
Tanziela Tanziela, Xiawei Dong, Jing Ye, Zengchao Guo, Hui Jiang, Zuhong Lu, Xiaohui Liu, Xuemei Wang
Summary: Exosomes, as natural nanocarriers, have shown great potential in the field of nanomedicine. They can be engineered or modified with different therapeutic substances to improve their specificity, efficiency, and safety in cancer therapy.
PROGRESS IN BIOMEDICAL ENGINEERING
(2022)
