Article
Chemistry, Analytical
Zuzhe Kang, Jiao Yang, Jingjing Jiang, Li Zhao, Yanrong Zhang, Qin Tu, Jinyi Wang, Mao-Sen Yuan
Summary: Pesticide pollution is a severe challenge for food quality and human safety. A new turn-on fluorescent chemosensor has been successfully developed in this study for sensitive, selective, and rapid detection of the pesticide paraquat. The chemosensor utilizes the host-guest strategy and aggregation-induced emission to achieve fluorescence enhancement. It shows good detection performance in real samples and living zebrafish.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Applied
Yu-Ting Zeng, Si-Yu Gao, Kaspars Traskovskis, Baoxiang Gao, Xiang-Kui Ren
Summary: The novel tetraphenylethylene derivative TPE-POSS was designed as a turn-on fluorescent sensor for detecting F-. Experimental results demonstrated its excellent detection ability, high selectivity, and sensitivity to F-. The collapse of POSS nanocages due to Si-O bond cleavage triggers the AIE activity of TPE luminogens.
Article
Chemistry, Applied
Tao Tao, Dongsheng Fang, Yunyun Chen, Yuting Fan, Haijie Lu
Summary: Aggregation-induced fluorescent materials, specifically TPE functionalized oligothiophenes, show potential for effective detection of explosives, with a balance between aggregation-induced emission and aggregation-caused quenching phenomena. Experimental results demonstrate the influence of TPE end-caps on energy level convergence.
Article
Chemistry, Applied
Nagendra Kalva, Chinh Hoang Tran, Min Woong Lee, Rimesh Augustine, Soo Jeong Lee, Il Kim
Summary: This study developed a facile synthesis method for AIE-active HPGs and designed a solid-state sensor for detecting nitroaromatic explosives. The resulting AIE-active HPGs showed excellent AIE characteristics and high sensitivity towards nitro compounds by conjugating tetraphenylethylene moieties onto the periphery of the HPGs.
Article
Chemistry, Analytical
Cheng Zhang, Xihao Pan, Siyao Cheng, Aming Xie, Wei Dong
Summary: With the increasingly severe international security situation, the demand for rapid and effective detection of explosives is growing. Research has found that by synthesizing two novel probes, it is possible to specifically detect the explosive FOX-7, providing the possibility for practical applications.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Dongying Pan, Yan Don, Yunhua Lu, Guoyong Xiao, Haijun Chi, Zhizhi Hu
Summary: In this study, a water-soluble fluorescent probe TPE-M was designed and synthesized for the detection of hypochlorous acid. The results showed that TPE-M exhibited excellent water solubility and could solely recognize hypochlorous acid. The detection limit of the fluorescent probe for hypochlorous acid was calculated to be 0.25 μM.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Physical
Xiaoyi Zhang, Shengjie Jiang, Guoliang Lin, Hongyu Guo, Fafu Yang
Summary: In this study, two new tetraphenylethylene-rufigallol-tetraphenylethylene triads were synthesized with good fluorescence properties and studied for their liquid crystalline behaviors. The compound with dodecyl chains demonstrated lower phase transition temperatures and a wider mesophase temperature range compared to the other compound. These findings suggest that symmetrical trimers are an effective approach for constructing novel fluorescence columnar liquid crystals.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Physical
Xiaoyi Zhang, Guoliang Lin, Hongyu Guo, Fafu Yang
Summary: This study reported two novel liquid crystals with good fluorescence in aggregated states, synthesized by a simple procedure. The columnar liquid crystalline behaviors and AIE fluorescence properties of the compounds were confirmed, showing that the properties can be tuned by the lengths of the terminal alkyl chains.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Materials Science, Multidisciplinary
Mandana Dilamian, Majid Joghataei, Zahra Ashrafi, Christoph Bohr, Sanjay Mathur, Hajar Maleki
Summary: Fibrous aerogels, a new class of aerogels based on advanced 1D nanofibers, stand out for their ease of processability, versatility, and multifunctionality. Combining the properties of aerogels and electrospun nanofibers, they offer superior mechanical properties and additional functionalities, with the possibility of selecting a wide range of materials and tunable porosity.
APPLIED MATERIALS TODAY
(2021)
Article
Chemistry, Multidisciplinary
Anna Brzechwa-Chodzynska, Grzegorz Markiewicz, Piotr Cecot, Jack Harrowfield, Artur R. Stefankiewicz
Summary: In this study, we describe the self-assembly of a tetraphenylethylene (TPE) derivative with amino acid substitution into a hydrogen-bonded dimeric capsule. Depending on the conditions, the TPE derivative exhibits bluish photoluminescence with QYs up to 24% due to the AIE effect and excimer formation.
CHEMICAL COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Ratan W. Jadhav, Sopan M. Wagalgave, Bajarang Kumbhar, Rushikesh M. Khadake, Ambadas B. Rode, Sidhanath Bhosale, Sheshanath Bhosale
Summary: A novel tetraphenylethylene functionalized aminoglycoside antibiotic kanamycin has been synthesized and characterized. The probe showed strong affinity towards bovine serum albumin (BSA) compared to other biological competitors. UV-Vis absorption and fluorescence emission spectroscopy revealed the recognition of BSA. The fluorescence quenching efficiency and binding constant were determined, and molecular docking study provided insight into the detailed interactions between the probe and BSA.
SCIENTIFIC REPORTS
(2022)
Article
Polymer Science
Haoying Wang, Fangyu Wang, Pengpeng Deng, Jinping Zhou
Summary: Functional polymer based on renewable material MC was modified with TPE to form a fluorescent derivative with thermoresponsive and biocompatible properties, suitable for bioimaging applications.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Chemistry, Applied
Feng-Ying Ye, Ming Hu, Wei Yu, Yan-Song Zheng
Summary: In this study, a sulfur-containing tetraphenylethylene tetracycle tetrathioether with high yield was synthesized, which exhibited exceptional selectivity and sensitivity towards palladium ions and enabled visual detection. The probe displayed aggregation-induced emission enhancement and 100% fluorescence quantum yield in the aggregation state, making it a promising candidate for detecting palladium ions.
Article
Chemistry, Multidisciplinary
Xiang Li, Qin Zhou, Miao Zhu, Wei Chen, Beibei Wang, Ye Sha, Hong Yan
Summary: A novel star-shaped molecule based on TPE-o-carborane with a triphenylamine core has been synthesized, showing an improved luminescent quantum yield of 62% in the solid state.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Lian Zhou, Wei Meng, Lin Sun, Lin Du, Xiaopeng Xuan, Jun Zhang
Summary: A study introduced an organic functional group to distinguish the four phenyl rings of tetraphenylethylene, and determined the in situ temperature-dependent crystal structures to show conformational changes of tert-butyl (3-(1,2,2-triphenylvinyl)phenyl)carbamate (BTPC). The isotropic displacement parameters of each phenyl further confirmed the inequivalent vibrations of the molecule due to the crystal's anisotropy.
Article
Engineering, Environmental
Jiaojun Wei, Pan Ran, Qiuyu Li, Jinfu Lu, Long Zhao, Yuan Liu, Xiaohong Li
Summary: The development of injectable hyaluronic acid hydrogels with bone marrow mesenchymal stem cell spheroids and short fiber fillers demonstrates potential for cartilage lesion repair. Results show that the approach can promote chondrogenic differentiation, extracellular matrix production, and inflammation reduction in osteochondral defects and osteoarthritis treatment.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Biomedical
Songzhi Xie, Chuanfei Mo, Wenxiong Cao, Shuang Xie, Shang Li, Zhanlin Zhang, Xiaohong Li
Summary: This study developed rod-shaped tubular micromotors for efficient penetration and thorough destruction of thrombi. The encapsulation of urokinase (uPA) into micromotors extended the half-life and increased bioavailability. The motion propelled by E. coli Nissle 1917 (EcN) enhanced the adsorption capacities of the micromotors. Fucoidan-mediated targeting improved thrombolysis capacity. In the treatment of venous thrombi in mice, the micromotors completely removed the blood clots and alleviated bleeding.
ACTA BIOMATERIALIA
(2022)
Article
Chemistry, Multidisciplinary
Qingjie Liu, Shuang Xie, Duan Fan, Tianpeng Xie, Guilan Xue, Xue Gou, Xiaohong Li
Summary: Biomimetic piezoelectric scaffolds with gradient piezoelectric properties were fabricated to induce the integrated osteochondral differentiation of rat MSCs. The piezoelectric potential positively modulated cell adhesion, intracellular calcium transients, Ca2+ binding proteins, and differentiation-related genes. The scaffold integrated osteogenic and chondrogenic differentiation on different areas, providing a smooth transition between cartilage and bone.
Article
Engineering, Biomedical
Maohua Chen, Jingjing Zhou, Pan Ran, Fangmei Lei, Jie Meng, Junwu Wei, Xiaohong Li
Summary: Developing novel approaches to combat bacterial resistance is crucial. In this study, amphiphilic antimicrobial copolymers, black phosphorus quantum dots, and S-nitrosocysteamine are assembled into nanoparticles, achieving synergistic antibacterial efficacy. This approach shows promising potential in promoting wound recovery and suppressing inflammatory cells.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Engineering, Biomedical
Shuang Xie, Kun Huang, Jiawen Peng, Yuan Liu, Wenxiong Cao, Dandan Zhang, Xiaohong Li
Summary: This study developed self-propelled nanomotors for the treatment of diabetic foot ulcers. The nanomotors released nitric oxide in the biofilm microenvironment to effectively kill bacteria and stimulate angiogenesis. Experimental results demonstrated that the treatment with nanomotors successfully eliminated bacterial infections and promoted wound healing.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Pan Ran, Huan Zheng, Wenxiong Cao, Xinwei Jia, Guiyuan Zhang, Yuan Liu, Xiaohong Li
Summary: This study developed injectable theranostic hydrogels for real-time diagnosis of infected wounds, imaging-guided antibacterial photodynamic therapy, and effective removal of bacterial debris. The hydrogels exhibited strong mechanical properties, self-healing ability, and the capability to remove bacterial debris through photothermal effect. The hydrogel dressing change significantly accelerated the healing of infected wounds by relieving oxidative stress, regulating inflammatory factors, promoting collagen deposition, and stimulating angiogenesis.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Engineering, Biomedical
Pan Ran, Tian Xia, Huan Zheng, Fangmei Lei, Zhanlin Zhang, Junwu Wei, Xiaohong Li
Summary: An injectable theranostic hydrogel was developed for long-term imaging of infected wounds, detection of infection recurrence, and on-demand bactericidal effect without antibiotics. The hydrogel exhibited reversible naked-eye diagnosis and photodynamic therapy, utilizing light-triggered gelation and color changes that could be monitored with a smart phone.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Biomedical
Zixin Zhu, Xue Gou, Laiyi Liu, Tian Xia, Jiayi Wang, Yimeng Zhang, Chenjun Huang, Wei Zhi, Ran Wang, Xiaohong Li, Shengnian Luo
Summary: A dynamically evolving antibacterial and repair-promoting nanocomposite (NCs) was designed by in situ self-assembling of zeolitic imidazolate framework-8 (ZIF-8) on the surface of barium titanate (BTO) and further loading with a small amount of ciprofloxacin (CIP). The combination of pH-stimulated drug delivery and ultrasound-controlled sonodynamics has the potential to dynamically evolve in infected wound sites, offering a multifunctional therapy.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Biomedical
Jie Meng, Peng Zhang, Qingjie Liu, Pan Ran, Shuang Xie, Junwu Wei, Xiaohong Li
Summary: Antibacterial electrotherapy using near-infrared illumination of pyroelectric nanoparticles has been developed to address the effectiveness and safety concerns in the antibacterial treatment. The Janus tBT@PDA NPs, obtained by capping polydopamine on tetragonal BaTiO3 NPs followed by ciprofloxacin loading, generate photothermal and pyroelectric effects under NIR illumination. The pyroelectric Janus nanomotors demonstrate synergistic PEDT/photothermal/antibiotic effects to enhance antibacterial efficacy while avoiding excessive heat, ROS, and antibiotic doses.
ACTA BIOMATERIALIA
(2023)
Article
Chemistry, Multidisciplinary
Kun Wei, Songzhi Xie, Zhao Zhang, Zhanlin Zhang, Wenxiong Cao, Qibo Fang, Xiaohong Li
Summary: Pickering emulsions are more resistant to droplet coalescence than surfactant-stabilized emulsions. Janus fiber fragments (JFs) were prepared by electrospinning poly(styrene-maleic anhydride) (PSMA) derivatives and cryosectioning aligned fibers, followed by conjugation of hydrophobic and hydrophilic ligands. JFs showed high stability and could be reused for oil harvesting.
Article
Engineering, Biomedical
Junwu Wei, Yuan Liu, Yingxin Li, Zhanlin Zhang, Jie Meng, Shuang Xie, Xiaohong Li
Summary: To overcome the limitations of cancer phototherapy, researchers designed Janus pyroelectric nanoparticles (NPs) that generate self-powered motion and built-in electric fields. These NPs enhance tumor cell internalization and produce reactive oxygen species (ROS) for pyroelectric dynamic therapy (PEDT), leading to significant induction of tumor cell apoptosis and suppression of tumor growth. The asymmetrical photothermal effect of the Janus NPs creates thermophoretic force to enhance tumor diffusion and cellular uptake, resulting in boosted cytotoxicity and intracellular ROS levels. The incorporation of gold nanoparticles (Au NPs) further increases the photothermal effect and elevates cellular uptake rates, enhancing the antitumor efficacy.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Zhanlin Zhang, Hui Yan, Wenxiong Cao, Shuang Xie, Pan Ran, Kun Wei, Xiaohong Li
Summary: This study proposes a strategy that combines persistent luminescence (PL)-excited photothermal therapy (PTT), thermophoresis-propelled motion, and PL-triggered NO release for cancer phototherapy. The strategy allows for readily applicable treatment of deep tumors using ultrasonication. The enhanced cellular uptake, long-lasting PTT, and increased intracellular NO levels achieved through this strategy effectively inhibit tumor growth.
Article
Chemistry, Physical
Junwu Wei, Jing Xia, Xing Liu, Pan Ran, Guiyuan Zhang, Chaoming Wang, Xiaohong Li
Summary: Ce-doped hollow BaTiO3 nanoparticles were developed to improve the piezocatalytic effect through hollow structure and defect engineering, enhancing polarization, piezoelectric potential, and antibacterial therapy.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2023)
Article
Materials Science, Biomaterials
Xinyan Tao, Yuan Liu, Zhenhua Ding, Shuang Xie, Wenxiong Cao, Xiaohong Li
Summary: This study proposes a local administration strategy for obesity treatment using R-Ha(Chr) fiber rods loaded with chrysin and F-Ats(Rk) fiber fragments loaded with raspberry ketone. This strategy improves lipid metabolism, reduces inflammation, and leads to weight loss.
BIOMATERIALS SCIENCE
(2023)
Article
Materials Science, Biomaterials
Jiawen Peng, Shuang Xie, Kun Huang, Pan Ran, Junwu Wei, Zhanlin Zhang, Xiaohong Li
Summary: This study proposes the use of self-propelled nanomotors to enhance biofilm infiltration, bacterial destruction, and endotoxin clearance, thereby accelerating the healing of infected burn wounds. The nanomotors release nitric oxide to destroy bacteria and bind with the bacteria to remove endotoxins. Animal experiments showed that the infected wounds were completely healed and exhibited skin features similar to normal skin after treatment with the nanomotors.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)