Dihydrofolate reductase 19-bp deletion polymorphism modifies the association of folate status with memory in a cross-sectional multi-ethnic study of adults

Homocysteine lowering, B vitamins, and cognitive aging

(2015) A David Smith et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

B-vitamin trials meta-analysis: less than meets the eye

(2015) Peter Garrard et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Effects of polymorphisms in endothelial nitric oxide synthase and folate metabolizing genes on the concentration of serum nitrate, folate, and plasma total homocysteine after folic acid supplementation: A double-blind crossover study

(2015) Rona Cabo et al.   NUTRITION

Fortification of Flour with Folic Acid

(2015) Robert J. Berry et al.   FOOD AND NUTRITION BULLETIN

Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals

(2014) Robert Clarke et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Folic acid handling by the human gut: implications for food fortification and supplementation

(2014) Imran Patanwala et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Low Folate Levels Are Associated with Reduced Risk of Colorectal Cancer in a Population with Low Folate Status

(2014) B. Gylling et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Revised D-A-CH intake recommendations for folate: how much is needed?

(2014) M B Krawinkel et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recycling

(2013) Jennifer Whitsett et al.   FREE RADICAL BIOLOGY AND MEDICINE

B-vitamins for neuroprotection: Narrowing the evidence gap

(2012) Yaarit Nachum-Biala et al.   BIOFACTORS

The Emerging Role of Unmetabolized Folic Acid in Human Diseases: Myth or Reality?

(2012) Rima Obeid et al.   CURRENT DRUG METABOLISM

Status of Vitamins B-12 and B-6 but Not of Folate, Homocysteine, and the Methylenetetrahydrofolate Reductase C677T Polymorphism Are Associated with Impaired Cognition and Depression in Adults

(2012) Denish Moorthy et al.   JOURNAL OF NUTRITION

Vitamin B-12 and Folate Status in Relation to Decline in Scores on the Mini-Mental State Examination in the Framingham Heart Study

(2012) Martha Savaria Morris et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Serum unmetabolized folic acid in a nationally representative sample of adults ≥60 years in the United States, 2001–2002

(2012) ReganL. Bailey et al.   Food & Nutrition Research

Identification and Characterization of an Inborn Error of Metabolism Caused by Dihydrofolate Reductase Deficiency

(2011) Siddharth Banka et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Dihydrofolate Reductase Deficiency Due to a Homozygous DHFR Mutation Causes Megaloblastic Anemia and Cerebral Folate Deficiency Leading to Severe Neurologic Disease

(2011) Holger Cario et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial

(2011) Celeste A. Jager et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions

(2011) Krista S. Crider et al.   Nutrients

Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors

(2010) Martha Savaria Morris et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Boston Puerto Rican Health Study, a longitudinal cohort study on health disparities in Puerto Rican adults: challenges and opportunities

(2010) Katherine L Tucker et al.   BMC PUBLIC HEALTH

Dihydrofolate Reductase Gene Intronic 19-bp Deletion Polymorphisms in a Japanese Population

(2010) Hideki Hayashi et al.   Drug Metabolism and Pharmacokinetics

B vitamins and the aging brain

(2010) Jacob Selhub et al.   NUTRITION REVIEWS

Depression and Plasma Amyloid β Peptides in the Elderly With and Without the Apolipoprotein E4 Allele

(2009) Xiaoyan Sun et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

DHFR 19-bp insertion/deletion polymorphism and MTHFR C677T in adult acute lymphoblastic leukaemia: Is the risk reduction due to intracellular folate unbalancing?

(2009) Donato Gemmati et al.   AMERICAN JOURNAL OF HEMATOLOGY

Homocysteine Lowering and Cognition in CKD: The Veterans Affairs Homocysteine Study

(2009) Christopher B. Brady et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Critical Role for Tetrahydrobiopterin Recycling by Dihydrofolate Reductase in Regulation of Endothelial Nitric-oxide Synthase Coupling

(2009) Mark J. Crabtree et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake

(2009) S. W. Bailey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The 19-bp deletion of dihydrofolate reductase (DHFR), methylenetetrahydrofolate reductase (MTHFR) C677T, Factor V Leiden, prothrombin G20210A polymorphisms in cancer patients with and without thrombosis

(2008) Aydan Eroglu et al.   ANNALS OF HEMATOLOGY

An insertion/deletion polymorphism of the dihydrofolate reductase (DHFR) gene is associated with serum and red blood cell folate concentrations in women

(2008) Anna Stanisławska-Sachadyn et al.   HUMAN GENETICS

Population admixture associated with disease prevalence in the Boston Puerto Rican health study

(2008) Chao-Qiang Lai et al.   HUMAN GENETICS

High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease

(2008) Paul S. Aisen   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A 19-Base Pair Deletion Polymorphism in Dihydrofolate Reductase Is Associated with Increased Unmetabolized Folic Acid in Plasma and Decreased Red Blood Cell Folate

(2008) Renee D. Kalmbach et al.   JOURNAL OF NUTRITION