Genetic backgrounds and modifier genes of NTD mouse models: An opportunity for greater understanding of the multifactorial etiology of neural tube defects

High-resolution genetic localization of a modifying locus affecting disease severity in the juvenile cystic kidneys (jck) mouse model of polycystic kidney disease

(2016) David R. Beier   MAMMALIAN GENOME

The orphan GPCR, Gpr161, regulates the retinoic acid and canonical Wnt pathways during neurulation

(2015) Bo I. Li et al.   DEVELOPMENTAL BIOLOGY

Genetic Modifiers and Oligogenic Inheritance

(2015) M. Kousi et al.   Cold Spring Harbor Perspectives in Medicine

Genetic, Epigenetic, and Environmental Contributions to Neural Tube Closure

(2014) Jonathan J. Wilde et al.   Annual Review of Genetics

Neural Tube Defects

(2014) Nicholas D.E. Greene et al.   Annual Review of Neuroscience

Planar cell polarity gene mutations contribute to the etiology of human neural tube defects in our population

(2014) Patrizia De Marco et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Systematic Review and Meta-analyses: Fever in Pregnancy and Health Impacts in the Offspring

(2014) J. W. Dreier et al.   PEDIATRICS

2012 Update on global prevention of folic acid-preventable spina bifida and anencephaly

(2013) Monica E. Youngblood et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

IsLMNB1a susceptibility gene for neural tube defects in humans?

(2013) Alexis Robinson et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel–Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and Wnt signalling defects

(2013) Zakia A. Abdelhamed et al.   HUMAN MOLECULAR GENETICS

Mouse as a model for multifactorial inheritance of neural tube defects

(2012) Irene E. Zohn   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Genome-wide screen of human bromodomain-containing proteins identifies Cecr2 as a novel DNA damage response protein

(2012) Seul-Ki Lee et al.   MOLECULES AND CELLS

Modifier Genes and the Plasticity of Genetic Networks in Mice

(2012) Bruce A. Hamilton et al.   PLoS Genetics

Lamin B1 Polymorphism Influences Morphology of the Nuclear Envelope, Cell Cycle Progression, and Risk of Neural Tube Defects in Mice

(2012) Sandra C. P. De Castro et al.   PLoS Genetics

Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice

(2011) Anna E Beaudin et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development

(2011) Christine E. Dawe et al.   DEVELOPMENTAL DYNAMICS

CECR2 Is Involved in Spermatogenesis and Forms a Complex with SNF2H in the Testis

(2011) Peter J. Thompson et al.   JOURNAL OF MOLECULAR BIOLOGY

Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes

(2011) Megan K. Kooistra et al.   PHYSIOLOGICAL GENOMICS

Cecr2 mutations causing exencephaly trigger misregulation of mesenchymal/ectodermal transcription factors

(2010) Nicholas A. Fairbridge et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Understanding diabetic teratogenesis: Where are we now and where are we going?

(2010) Sheller Zabihi et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure

(2010) Muriel J. Harris et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure

(2010) J. Mao et al.   DEVELOPMENT

Epidemiologic and genetic aspects of spina bifida and other neural tube defects

(2010) Kit Sing Au et al.   Developmental Disabilities Research Reviews

The Biology of Chromatin Remodeling Complexes

(2009) Cedric R. Clapier et al.   Annual Review of Biochemistry

Maternal Overweight and Obesity and the Risk of Congenital Anomalies

(2009) Katherine J. Stothard et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic background influences embryonic lethality and the occurrence of neural tube defects in Men1 null mice: relevance to genetic modifiers

(2009) Manuel C Lemos et al.   JOURNAL OF ENDOCRINOLOGY

SHMT1 and SHMT2 Are Functionally Redundant in Nuclear De novo Thymidylate Biosynthesis

(2009) Donald D. Anderson et al.   PLoS One

Sall1, Sall2, and Sall4 Are Required for Neural Tube Closure in Mice

(2008) Johann Böhm et al.   AMERICAN JOURNAL OF PATHOLOGY

Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos

(2008) Wenchu Lin et al.   DEVELOPMENTAL DYNAMICS

Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/β-catenin and the planar cell polarity pathways during early trunk formation in mouse

(2008) Wataru Satoh et al.   GENESIS

Cytoplasmic Serine Hydroxymethyltransferase Regulates the Metabolic Partitioning of Methylenetetrahydrofolate but Is Not Essential in Mice

(2008) Amanda J. MacFarlane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Extracellular Domain of Lrp5/6 Inhibits Noncanonical Wnt Signaling In Vivo

(2008) Vitezslav Bryja et al.   MOLECULAR BIOLOGY OF THE CELL

Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects

(2008) Ron Korstanje et al.   PHYSIOLOGICAL GENOMICS

The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development

(2008) P. G. Matteson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA