The distribution of fitness effects in an uncertain world

The Utility of Fisher's Geometric Model in Evolutionary Genetics

(2014) O. Tenaillon   Annual Review of Ecology Evolution and Systematics

The temporal distribution of directional gradients under selection for an optimum

(2014) Luis-Miguel Chevin et al.   EVOLUTION

FISHER'S GEOMETRIC MODEL WITH A MOVING OPTIMUM

(2014) Sebastian Matuszewski et al.   EVOLUTION

A Bayesian MCMC Approach to Assess the Complete Distribution of Fitness Effects of New Mutations: Uncovering the Potential for Adaptive Walks in Challenging Environments

(2014) C. Bank et al.   GENETICS

Fisher’s Geometrical Model Emerges as a Property of Complex Integrated Phenotypic Networks

(2014) Guillaume Martin   GENETICS

Balancing Selection in Species with Separate Sexes: Insights from Fisher's Geometric Model

(2014) T. Connallon et al.   GENETICS

The deleterious mutation load is insensitive to recent population history

(2014) Yuval B Simons et al.   NATURE GENETICS

Cryptic genetic variation: evolution's hidden substrate

(2014) Annalise B. Paaby et al.   NATURE REVIEWS GENETICS

The Population Genetics of Evolutionary Rescue

(2014) H. Allen Orr et al.   PLoS Genetics

The spatial patterns of directional phenotypic selection

(2013) Adam M. Siepielski et al.   ECOLOGY LETTERS

SHIFTING FITNESS LANDSCAPES IN RESPONSE TO ALTERED ENVIRONMENTS

(2013) Ryan T. Hietpas et al.   EVOLUTION

SENSITIVITY OF THE DISTRIBUTION OF MUTATIONAL FITNESS EFFECTS TO ENVIRONMENT, GENETIC BACKGROUND, AND ADAPTEDNESS: A CASE STUDY WITHDROSOPHILA

(2013) Alethea D. Wang et al.   EVOLUTION

Implications of sex-specific selection for the genetic basis of disease

(2013) Edward H. Morrow et al.   Evolutionary Applications

Rapid evolution of quantitative traits: theoretical perspectives

(2013) Michael Kopp et al.   Evolutionary Applications

Evolutionary inevitability of sexual antagonism

(2013) T. Connallon et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Evolution of clonal populations approaching a fitness peak

(2012) I. Gordo et al.   Biology Letters

FISHER'S GEOMETRICAL MODEL OF FITNESS LANDSCAPE AND VARIANCE IN FITNESS WITHIN A CHANGING ENVIRONMENT

(2012) Xu-Sheng Zhang   EVOLUTION

Establishment of New Mutations in Changing Environments

(2012) Stephan Peischl et al.   GENETICS

Identifying sources of variation and the flow of information in biochemical networks

(2012) C. G. Bowsher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

COMPLEXITY, PLEIOTROPY, AND THE FITNESS EFFECT OF MUTATIONS

(2011) João Lourenço et al.   EVOLUTION

A Unified Treatment of the Probability of Fixation when Population Size and the Strength of Selection Change Over Time

(2011) D. Waxman   GENETICS

Fitness Landscapes: An Alternative Theory for the Dominance of Mutation

(2011) Federico Manna et al.   GENETICS

On the Fixation Process of a Beneficial Mutation in a Variable Environment

(2011) Hildegard Uecker et al.   GENETICS

Natural selection. I. Variable environments and uncertain returns on investment*

(2011) S. A. FRANK   JOURNAL OF EVOLUTIONARY BIOLOGY

Cost of Antibiotic Resistance and the Geometry of Adaptation

(2011) Ana Sousa et al.   MOLECULAR BIOLOGY AND EVOLUTION

Heterozygote advantage as a natural consequence of adaptation in diploids

(2011) D. Sellis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EVOLUTIONARY CONSTRAINT AND ECOLOGICAL CONSEQUENCES

(2010) Douglas J. Futuyma   EVOLUTION

Genomic patterns of pleiotropy and the evolution of complexity

(2010) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies

(2010) A. Eyre-Walker   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental duress and epistasis: how does stress affect the strength of selection on new mutations?

(2010) Aneil F. Agrawal et al.   TRENDS IN ECOLOGY & EVOLUTION

Abundant Genetic Variation + Strong Selection = Multivariate Genetic Constraints: A Geometric View of Adaptation

(2009) Bruce Walsh et al.   Annual Review of Ecology Evolution and Systematics

Toward a population genetic framework of developmental evolution: the costs, limits, and consequences of phenotypic plasticity

(2009) Emilie C. Snell-Rood et al.   BIOESSAYS

Fluctuating selection: the perpetual renewal of adaptation in variable environments

(2009) G. Bell   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Patterns of quantitative genetic variation in multiple dimensions

(2008) Mark Kirkpatrick   GENETICA

The Distribution of Beneficial and Fixed Mutation Fitness Effects Close to an Optimum

(2008) Guillaume Martin et al.   GENETICS