Article
Biochemistry & Molecular Biology
Nguyen Huy Hung, Pham Minh Quan, Prabodh Satyal, Do Ngoc Dai, Vo Van Hoa, Ngo Gia Huy, Le Duc Giang, Nguyen Thi Ha, Le Thi Huong, Vu Thi Hien, William N. Setzer
Summary: Essential oils have potential as environmentally friendly and safe pesticides, as well as therapeutic agents for Alzheimer's disease. Some plant species' essential oils showed good inhibition activity against acetylcholinesterase.
Article
Plant Sciences
Jiahui Sun, Peipei Sun, Chuanzhi Kang, Lanyue Zhang, Lanping Guo, Yaping Kou
Summary: In recent years, essential oils have gained wide attention for their extensive applications in natural functional ingredients, pharmaceutical preparations, biomedical products, and the cosmetics industry. This study analyzed the chemical compositions and biological activities of essential oils extracted from six Lamiaceae herbs, showing their excellent and diverse biological activities that make them perfect natural functional ingredients in antioxidant, antitumor, or anti-arthritic drugs.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Agronomy
Salvatore Barreca, Salvatore La Bella, Antonella Maggio, Mario Licata, Silvestre Buscemi, Claudio Leto, Andrea Pace, Teresa Tuttolomondo
Summary: The study aimed to improve the food shelf-life and aromatic flavor of extra-virgin olive oil by adding essential oils from medicinal and aromatic plants. The results suggest that essential oils have an antioxidant effect on olive oil.
Article
Agricultural Engineering
Lanyue Zhang, Mao Ye, Yaohui Shi, Haiping Zhu, Lejing Chi, Chunxing Pan, Yani Xu, Xi Zheng, Hongping Xiang, Chunlian Li
Summary: Essential oils extracted from Pogostemon cablin, Angelica dahurica, and Myristica fragrans plants exhibited strong anti-inflammatory and anti-microbial activities, as well as significant anti-oxidant properties. These oils were found to inhibit the production of inflammatory markers and showed potential use in food, fragrances, cosmetics, and health products.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Review
Biochemistry & Molecular Biology
Thais A. S. Oliveira, Mariana B. Santiago, Valmore H. P. Santos, Eliane O. Silva, Carlos H. G. Martins, Antonio E. M. Crotti
Summary: This review article provides an updated overview of the literature from 2011 to 2021 regarding the antibacterial activity of EOs against the main bacteria responsible for caries and periodontal diseases. The criteria for classifying the in vitro antibacterial activity of EOs has been updated, and the most promising results are highlighted.
CHEMISTRY & BIODIVERSITY
(2022)
Article
Plant Sciences
Giuseppe Amato, Lucia Caputo, Rosaria Francolino, Mara Martino, Vincenzo De Feo, Laura De Martino
Summary: Many studies have shown that certain essential oils have herbicidal effects and can be used as alternatives to chemical herbicides. In this study, the chemical composition of essential oils from two ecotypes of O. heracleoticum in Southern Italy was compared and their potential as natural herbicides was investigated using seeds of Raphanus sativus, Sinapis arvensis, and Lolium multiflorum. The study also evaluated the inhibitory activity of the essential oils on the alpha-amylase enzyme, which is involved in seed germination. The results showed that the essential oils exhibited herbicidal and alpha-amylase inhibitory activities, suggesting their potential for further exploration.
Review
Plant Sciences
Trifone D'Addabbo, Pinarosa Avato
Summary: Essential oils can be a valuable source of new food-safe and healthy nematicidal products due to their strong activity on crop pathogens and pests, as well as their low environmental persistence. Testing 16 different essential oils from various botanical origins and compositions revealed that most of them are highly suitable for formulating new safe nematicides.
Review
Plant Sciences
Babett Greff, Andras Saho, Erika Lakatos, Laszlo Varga
Summary: Soil-borne phytopathogens can cause significant losses to cereal and horticultural crops worldwide. Synthetic pesticides are still widely used, but the search for sustainable alternatives is becoming more urgent. The incorporation of botanicals and aromatic plants into agricultural practices can help control plant diseases, but their application needs to be carefully regulated to avoid negative impacts on soil fertility. This study reviews the efficiency of secondary metabolites from aromatic and medicinal plants as biopesticides against soil-borne plant pathogens, and highlights the potential of recycling waste from aromatic plant industries to improve soil health.
Article
Agricultural Engineering
Jeferson Adriano e Silva Assuncao, Diego da Silva Marcelino, Jessica Regina Sales Felisberto, Elsie Fraklin Guimaraes, George de Azevedo Queiroz, Ygor Jesse Ramos, Davyson de Lima Moreira
Summary: This study aimed to assess the post-harvest impact of UV-C irradiation on the metabolic profile of essential oils (EOs) from fresh leaves of Piper aduncum cultivated in Southeastern Brazil. The results showed that UV-C radiation can alter the relative percentage of specific chemical constituents, with a significant increase in the relative percentage of the compound dillapiole. This study suggests that UV-C irradiation may be a promising technique for enriching the dillapiole content in the essential oil of P. aduncum.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Plant Sciences
Svetlana V. Zhigzhitzhapova, Elena P. Dylenova, Bato V. Zhigzhitzhapov, Danaya B. Goncharova, Zhargal A. Tykheev, Vasiliy V. Taraskin, Oleg A. Anenkhonov
Summary: Plants of arid regions, such as Artemisia frigida, have developed essential oil compositions in response to heterogeneous factors, including climate. This study found that the composition of A. frigida essential oil varies significantly under different climatic conditions.
Article
Biochemistry & Molecular Biology
Aishwarya Chaure, Marketa Houdkova, Julien Antih, Klara Urbanova, Ivo Doskocil, Mukund Lal Naik, Khageshwar Singh Patel, Ladislav Kokoska
Summary: This study validates the efficacy of the broth macrodilution volatilization method for evaluating the antibacterial properties of essential oils (EOs) and demonstrates the growth-inhibitory effect of Indian medicinal plants on pneumonia-causing bacteria in both liquid and vapor phases. Among the EOs tested, Trachyspermum ammi EO exhibits the strongest antibacterial effect against Haemophilus influenzae. Chemical analysis reveals the main constituents of the EOs and identifies & alpha;-citral, cyperotundone, thymol, and & beta;-cymene as major compounds. This study highlights the therapeutic potential of Indian medicinal plants in inhalation therapy.
Article
Biochemistry & Molecular Biology
Maria Bailen, Cristina Illescas, Monica Quijada, Rafael Alberto Martinez-Diaz, Eneko Ochoa, Maria Teresa Gomez-Munoz, Juliana Navarro-Rocha, Azucena Gonzalez-Coloma
Summary: The antiparasitic activity of 23 essential oils from plants was evaluated against Leishmania and Phytomonas, finding that oils from Satureja montana, Thymus vulgaris, Mentha suaveolens, and Lavandula luisieri exhibited the best activity. Steam distillation increased the content of certain compounds in the oils. Thymol and carvacrol were identified as the major active components.
Article
Veterinary Sciences
Michelina Pusceddu, Ignazio Floris, Nicoletta P. Mangia, Alberto Angioni, Alberto Satta
Summary: The study found that Thymus herba-barona, Thymus capitatus, and Cinnamomum zeylanicum essential oils have good inhibitory, fungicidal, and sporicidal activity against the etiological agent of chalkbrood in honey bees. Further research is needed to evaluate the potential effects of these essential oils on bees and hive products.
VETERINARY SCIENCES
(2021)
Article
Polymer Science
Roxana Gheorghita Puscaselu, Andrei Lobiuc, Ioan Ovidiu Sirbu, Mihai Covasa
Summary: This study developed biopolymer-based films with improved properties by adding essential oils such as lemon, orange, grapefruit, cinnamon, clove, chamomile, ginger, eucalyptus or mint. Lemon essential oil prevented mass reduction but degraded the microstructure and elasticity. Mint and ginger essential oils resulted in films with a more homogenous microstructure, but higher concentrations led to pore appearance and color modifications.
Article
Infectious Diseases
Atika Ailli, Nadia Handaq, Hanane Touijer, Aman Allah Gourich, Aziz Drioiche, Khalid Zibouh, Brahim Eddamsyry, Fadoua El Makhoukhi, Aicha Mouradi, Yousef A. Bin Jardan, Mohammed Bourhia, Abdelhakim Elomri, Touriya Zair
Summary: This study examined the chemical composition and antioxidant and antimicrobial activities of the essential oils (EOs) of six different plants. The analysis revealed different compounds in each EO and demonstrated their antioxidant and antimicrobial properties. These EOs can serve as natural alternatives and be used as additives in cosmetics.
Letter
Pharmacology & Pharmacy
Jun Miura, Celestino Obua, Catherine Abbo, Tomonori Tateishi, Sunao Kaneko
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Entomology
Abdullah Haris, Muhammad Azeem, Muhammad Binyameen
Summary: This study evaluated the potential of Carpesium abrotanoides essential oil as a mosquito repellent, and tested its major constituents. The results showed that both the essential oil and trans-nerolidol had good repellent effects against Aedes aegypti, comparable to the popular DEET repellent.
JOURNAL OF MEDICAL ENTOMOLOGY
(2022)
Article
Chemistry, Applied
Joham Sarfraz Ali, Muhammad Azeem, Abdul Mannan, Muhammad Zia
Summary: The essential oil extracted from Monotheca buxifolia leaves has a diverse chemical composition and multiple biological activities, including antioxidant and antibacterial properties. The study suggests that the oil has therapeutic potential and could be further explored for medicinal purposes.
NATURAL PRODUCT RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Muhammad Azeem, Tariq Zaman, Arshad Mehmood Abbasi, Muhammad Abid, Raimondas Mozuraitis, Mona S. Alwahibi, Mohamed Soliman Elshikh
Summary: This study aimed to identify plant-based natural pesticides to control Tribolium castaneum and Aspergillus flavus in stored grains. Essential oils from Chenopodium ambrosioides and Erigeron canadensis showed excellent toxicity against T. castaneum and exhibited good anti-fungal activity against A. flavus. These findings suggest that these essential oils can play an important role in protecting stored grains from contamination by T. castaneum and A. flavus.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Plant Sciences
Sunjeet Kumar, Raza Ahmad, Sidra Saeed, Muhammad Azeem, Raimondas Mozuraitis, Anna-Karin Borg-Karlson, Guopeng Zhu
Summary: This study investigates the aroma composition and chemical components of essential oils in different coriander cultivars. The findings show significant differences in volatile aroma components of fresh coriander leaves among cultivars, but similar chemistry and antibacterial activity in essential oils.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biotechnology & Applied Microbiology
Christine K. Karungi, Edith K. Wakida, Godfrey Z. Rukundo, Zohray M. Talib, Jessica E. Haberer, Celestino Obua
Summary: This study aimed to evaluate the capacity of lay health workers in rural Uganda to provide community-based care and management for people with dementia, as well as implement the knowledge and skills acquired. The results showed that after the training, the lay health workers had a basic understanding of dementia and were able to sensitize the communities. However, they faced challenges in differentiating early dementia signs from superstitious beliefs.
BIOMED RESEARCH INTERNATIONAL
(2022)
Review
Health Care Sciences & Services
Mark Mohan Kaggwa, Godfrey Zari Rukundo, Edith K. Wakida, Samuel Maling, Baker Makaya Sserumaga, Letizia Maria Atim, Celestino Obua
Summary: The study found that the suicide rate in Uganda has significantly increased since the onset of the COVID-19 pandemic. The annual incidence rates of suicide attempts and completed suicides were approximately 60 per 100,000 people and 3 per 100,000 people, respectively. The number of suicide attempts rose following the first month of COVID-19 lockdown, with poisoning being the most common method. This study highlights the urgent need for proactive interventions, such as controlling pesticides and herbicides, to prevent suicide in the community, especially during pandemic conditions.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2022)
Article
Education, Scientific Disciplines
Edith K. Wakida, Godfrey Z. Rukundo, Clara Atuhaire, Christine K. Karungi, Edward Kumakech, Jessica E. Haberer, Zohray M. Talib, Celestino Obua
Summary: The study evaluated the perceptions of undergraduates and mentors on the appropriateness, acceptability, and feasibility of a mentored seed-grant program by HEPI-TUITAH on HIV training in Uganda. Most participants found the program acceptable, appropriate, and feasible for health professions undergraduate students, emphasizing the value of interprofessional education and data collection experience.
ADVANCES IN MEDICAL EDUCATION AND PRACTICE
(2022)
Article
Plant Sciences
Ken Keefover-Ring, Craig H. Carlson, Brennan Hyden, Muhammad Azeem, Lawrence B. Smart
Summary: Secondary chemistry mediates important ecological interactions in plants, and this study examines the genetic basis of the sexually dimorphic secondary chemistry in male and female Salix purpurea willow catkins. The research identifies the specific chemicals produced by each sex, maps quantitative trait loci (QTL) for these traits, and identifies candidate genes associated with the synthesis of these chemicals. The findings contribute to our understanding of the evolution and maintenance of dioecy in plants.
JOURNAL OF EXPERIMENTAL BOTANY
(2022)
Article
Parasitology
Sajid Iqbal, Fawad Ahmed Khan, Abdullah Haris, Raimondas Mozuraitis, Muhammad Binyameen, Muhammad Azeem
Summary: This study evaluated the repellent potential of essential oils from Lepidium pinnatifidum, Mentha longifolia, Origanum vulgare, and Agrimonia eupatoria against Aedes aegypti mosquitoes. Results showed that essential oils from Mentha longifolia and Origanum vulgare exhibited high mosquito repellent activity and longevity, making them potential alternatives to synthetic chemicals for protecting humans from mosquito bites.
EXPERIMENTAL PARASITOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Abdullah Haris, Muhammad Azeem, Muhammad Ghazanfar Abbas, Muhammad Mumtaz, Raimondas Mozuraitis, Muhammad Binyameen
Summary: Repellents made with essential oils are effective in protecting people from outdoor mosquitoes. The study found that Perovskia atriplicifolia, Citrus reticulata (fruit peels), C. reticulata (leaves), Mentha longifolia, and Dysphania ambrosioides were the most effective essential oils in repelling Aedes aegypti mosquitoes. P. atriplicifolia showed the longest repellent effect, followed by C. reticulata (peels), M. longifolia, and C. reticulata (leaves). The study also identified the major constituents of these essential oils. The results could contribute to the development of plant-based commercial repellents for dengue mosquitoes.
Article
Biology
Muhammad Ghazanfar Abbas, Abdullah Haris, Muhammad Binyameen, Abdul Nazir, Raimondas Mozuraitis, Muhammad Azeem
Summary: Plant essential oils, such as those extracted from Mentha longifolia and Erigeron bonariensis, have shown potential as mosquito repellents and larvicides against Aedes aegypti mosquitoes. These oils can effectively control both larvae and adult mosquitos, making them a cost-effective and environmentally friendly alternative to synthetic repellents.
Article
Health Care Sciences & Services
Edith K. Wakida, Celestino Obua, Jessica E. Haberer, Stephen J. Bartels
Summary: This study aims to understand the role and challenges of the district health management teams (DHMT) in mental health integration in Uganda, and propose solutions for improvement. The findings suggest that DHMT members lack knowledge and data on mental health integration, and recommend training, standard outcome reports, and practical tools for better support and supervision.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2023)
Article
Chemistry, Multidisciplinary
Palwasha Khan, Amara Waheed, Muhammad Azeem, Amna Parveen, Muhammad Arfat Yameen, Jamshed Iqbal, Muhammad Ali, Shiwei Wang, Sadaf Qayyum, Awal Noor, Tatheer Alam Naqvi
Summary: This study evaluated the potential of Tagetes minuta essential oil (EO) to inhibit biofilm and related virulence factors. The EO significantly inhibited virulence factors linked with quorum sensing (QS), such as pyocyanin production, protease production, and swarming motility. It also inhibited biofilm formation, indicating that the inhibition of biofilm by EO is through the inhibition of the QS pathway. However, the EO showed limited antibacterial activity. The study confirmed that the EO interferes with the QS pathway that controls various virulence factors.
Article
Infectious Diseases
David Oyet, Vallence Niyonzima, Gideon Akol, Emmanuel Onyait, Daphine Twinomugisha, Doreen Kawala Wambera, Edith K. Wakida, Celestino Obua
Summary: This study explores the barriers and facilitators to the utilization of community drug distribution points (CDDPs) among people living with HIV (PLHIV) in south-western Uganda. The results show that peer support, positive attitudes from primary healthcare providers, satisfaction with HIV services, and accessibility of anti-retroviral medication services are major facilitators for CDDP utilization. Stigma, lack of physical infrastructure, and lack of comprehensive services are identified as the main barriers. The study suggests improving physical infrastructure at CDDP sites, protecting the privacy and confidentiality of PLHIV, and addressing stigma through interventions from primary healthcare providers and other stakeholders.
HIV AIDS-RESEARCH AND PALLIATIVE CARE
(2023)
