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Circular RNAs in cancer: an emerging key player

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Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

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Differential Expression of Circular RNAs in Glioblastoma Multiforme and Its Correlation with Prognosis

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Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma

(2016) Jakob Hedegaard et al.   CANCER CELL

miRNA-124 modulates lung carcinoma cell migration and invasion

(2016) Zhengliang Li et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

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Silencing of cZNF292 circular RNA suppresses human glioma tube formation via the Wnt/β-catenin signaling pathway

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The Landscape of microRNA Targeting in Prostate Cancer Defined by AGO-PAR-CLIP

(2016) Mark P. Hamilton et al.   NEOPLASIA

Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance

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The RNA Binding Protein Quaking Regulates Formation of circRNAs

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Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

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Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity

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Exon Circularization Requires Canonical Splice Signals

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Analysis of Intron Sequences Reveals Hallmarks of Circular RNA Biogenesis in Animals

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cir-ITCH Plays an Inhibitory Role in Colorectal Cancer by Regulating the Wnt/β-Catenin Pathway

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Identification and Characterization of Circular RNAs As a New Class of Putative Biomarkers in Human Blood

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Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

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circRNA Biogenesis Competes with Pre-mRNA Splicing

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Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types

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(2014) Laura S. Mertens et al.   Nature Reviews Urology

The Health Economics of Bladder Cancer: An Updated Review of the Published Literature

(2014) Christina Yeung et al.   PHARMACOECONOMICS

Circular RNA Is Expressed across the Eukaryotic Tree of Life

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Circular RNA and miR-7 in Cancer

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Natural RNA circles function as efficient microRNA sponges

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Circular RNAs are a large class of animal RNAs with regulatory potency

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Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif

(2013) Mark P. Hamilton et al.   Nature Communications

Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

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(2012) Philip J. Uren et al.   BIOINFORMATICS

MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma

(2012) YuXiang Fang et al.   HEPATOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

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(2012) Ben Langmead et al.   NATURE METHODS

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

(2012) Julia Salzman et al.   PLoS One

Circular RNAs are abundant, conserved, and associated with ALU repeats

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Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes

(2011) M. F. Lin et al.   GENOME RESEARCH

miRNA-7 Attenuation in Schwannoma Tumors Stimulates Growth by Upregulating Three Oncogenic Signaling Pathways

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miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma

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microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma

(2008) B. Kefas et al.   CANCER RESEARCH

MicroRNA-7, a Homeobox D10 Target, Inhibits p21-Activated Kinase 1 and Regulates Its Functions

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Regulation of Epidermal Growth Factor Receptor Signaling in Human Cancer Cells by MicroRNA-7

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