Revolutionizing Therapeutic Drug Monitoring with the Use of Interstitial Fluid and Microneedles Technology

A Comprehensive Review on the Predictive Performance of the Sheiner-Tozer and Derivative Equations for the Correction of Phenytoin Concentrations

(2016) Tony K. L. Kiang et al.   ANNALS OF PHARMACOTHERAPY

Therapeutic drug monitoring of mycophenolate in adult solid organ transplant patients: an update

(2016) Tony K. L. Kiang et al.   Expert Opinion on Drug Metabolism & Toxicology

Therapeutic Drug Monitoring of Vancomycin in Dermal Interstitial Fluid Using Dissolving Microneedles

(2016) Yukako Ito et al.   International Journal of Medical Sciences

Pharmacokinetic profile of methotrexate in psoriatic skin via the oral or subcutaneous route using dermal microdialysis showing higher methotrexate bioavailability in psoriasis plaques than in non-lesional skin

(2016) S.R. Quist et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Integrated hollow microneedle-optofluidic biosensor for therapeutic drug monitoring in sub-nanoliter volumes

(2016) Sahan A. Ranamukhaarachchi et al.   Scientific Reports

Self-powered microneedle-based biosensors for pain-free high-accuracy measurement of glycaemia in interstitial fluid

(2015) L.M. Strambini et al.   BIOSENSORS & BIOELECTRONICS

A Qualitative Review on the Pharmacokinetics of Antibiotics in Saliva: Implications on Clinical Pharmacokinetic Monitoring in Humans

(2015) Tony K. L. Kiang et al.   CLINICAL PHARMACOKINETICS

Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients

(2015) Jason A. Roberts et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Vancomycin serum concentrations do not adequately predict tissue exposure in diabetic patients with mild to moderate limb infections

(2015) Yukihiro Hamada et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Drug Distribution to Human Tissues: Prediction and Examination of the Basic Assumption in In Vivo Pharmacokinetics-Pharmacodynamics (PK/PD) Research

(2015) Patrick Poulin   JOURNAL OF PHARMACEUTICAL SCIENCES

A Paradigm Shift in Pharmacokinetic–Pharmacodynamic (PKPD) Modeling: Rule of Thumb for Estimating Free Drug Level in Tissue Compared with Plasma to Guide Drug Design

(2015) Patrick Poulin   JOURNAL OF PHARMACEUTICAL SCIENCES

Vancomycin Tissue Pharmacokinetics in Patients with Lower-Limb Infections via In Vivo Microdialysis

(2015) Seth T. Housman et al.   JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION

A LC–MS/MS method for therapeutic drug monitoring of carbamazepine, lamotrigine and valproic acid in DBS

(2015) Camilla Linder et al.   Bioanalysis

Hydrogel-Forming Microneedle Arrays Allow Detection of Drugs and Glucose In Vivo: Potential for Use in Diagnosis and Therapeutic Drug Monitoring

(2015) Ester Caffarel-Salvador et al.   PLoS One

Collection of Analytes from Microneedle Patches

(2014) Andrey V. Romanyuk et al.   ANALYTICAL CHEMISTRY

A Comprehensive Review on the Pharmacokinetics of Antibiotics in Interstitial Fluid Spaces in Humans: Implications on Dosing and Clinical Pharmacokinetic Monitoring

(2014) Tony K. L. Kiang et al.   CLINICAL PHARMACOKINETICS

Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?

(2014) J. M. Varghese et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Preferences of Adult Outpatients in Medical or Dental Care Settings for Giving Saliva, Urine or Blood for Clinical Testing

(2014) Sreenivas Koka et al.   JOURNAL OF THE AMERICAN DENTAL ASSOCIATION

Utility of noninvasive biomatrices in pharmacokinetic studies

(2013) Kanumuri Siva Rama Raju et al.   BIOMEDICAL CHROMATOGRAPHY

The Potential Role of Oral Fluid in Antidoping Testing

(2013) S. Anizan et al.   CLINICAL CHEMISTRY

Effect of microneedles shape on skin penetration and minimally invasive continuous glucose monitoring in vivo

(2013) Beelee Chua et al.   SENSORS AND ACTUATORS A-PHYSICAL

Microneedle-Mediated Minimally Invasive Patient Monitoring

(2013) Ryan F. Donnelly et al.   THERAPEUTIC DRUG MONITORING

Therapeutic Drug Monitoring of Antiepileptic Drugs by Use of Saliva

(2013) Philip N. Patsalos et al.   THERAPEUTIC DRUG MONITORING

Fundamentals of Population Pharmacokinetic Modelling

(2012) Catherine M. T. Sherwin et al.   CLINICAL PHARMACOKINETICS

Fundamentals of Population Pharmacokinetic Modelling

(2012) Tony K. L. Kiang et al.   CLINICAL PHARMACOKINETICS

A Minimally Invasive System for Glucose Area Under the Curve Measurement Using Interstitial Fluid Extraction Technology: Evaluation of the Accuracy and Usefulness with Oral Glucose Tolerance Tests in Subjects With and Without Diabetes

(2012) Kazuhiko Sakaguchi et al.   Diabetes Technology & Therapeutics

Aliskiren penetrates adipose and skeletal muscle tissue and reduces renin–angiotensin system activity in obese hypertensive patients

(2012) Michael Boschmann et al.   JOURNAL OF HYPERTENSION

Therapeutic Drug Monitoring in Interstitial Fluid: A Feasibility Study Using a Comprehensive Panel of Drugs

(2012) Tony K.L. Kiang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Advancing Prediction of Tissue Distribution and Volume of Distribution of Highly Lipophilic Compounds from a Simplified Tissue-Composition-Based Model as a Mechanistic Animal Alternative Method

(2012) Patrick Poulin et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Systematic Review of Efficacy, Pharmacokinetics, and Administration of Intraventricular Vancomycin in Adults

(2012) Karen Ng et al.   Neurocritical Care

Interstitial Fluid and Lymph Formation and Transport: Physiological Regulation and Roles in Inflammation and Cancer

(2012) Helge Wiig et al.   PHYSIOLOGICAL REVIEWS

Comparison of vancomycin concentrations in blood and interstitial fluid: a possible model for less invasive therapeutic drug monitoring

(2011) Urs O. Häfeli et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Does Olanzapine Warrant Clinical Pharmacokinetic Monitoring in Schizophrenia?

(2011) Erin Schwenger et al.   CLINICAL PHARMACOKINETICS

Risperidone in Schizophrenia: Is There a Role for Therapeutic Drug Monitoring?

(2011) Katherine Seto et al.   THERAPEUTIC DRUG MONITORING

The Role of Therapeutic Drug Monitoring of Imatinib in Patients with Chronic Myeloid Leukemia and Metastatic or Unresectable Gastrointestinal Stromal Tumors

(2011) Jennifer F T Teng et al.   THERAPEUTIC DRUG MONITORING

Increasing tumoral 5-fluorouracil concentrations during a 5-day continuous infusion: a microdialysis study

(2010) Inge R. H. M. Konings et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Interstitium: The next diagnostic and therapeutic platform in critical illness

(2010) Bala Venkatesh et al.   CRITICAL CARE MEDICINE

Application of Basic Pharmacokinetic Concepts to Analysis of Microdialysis Data

(2009) Claire Dahyot et al.   CLINICAL PHARMACOKINETICS

Pharmacokinetics and Therapeutic Drug Monitoring of Psychotropic Drugs in Pediatrics

(2009) Simona Pichini et al.   THERAPEUTIC DRUG MONITORING

Bioanalytical issues in patient-friendly sampling methods for therapeutic drug monitoring: focus on antiretroviral drugs

(2009) R ter Heine et al.   Bioanalysis

Measurement of xenobiotics in saliva: is saliva an attractive alternative matrix? Case studies and analytical perspectives

(2008) Ramesh Mullangi et al.   BIOMEDICAL CHROMATOGRAPHY

Application of prolonged microdialysis sampling in carboplatin-treated cancer patients

(2008) Inge R. H. M. Konings et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Does Oxcarbazepine Warrant Therapeutic Drug Monitoring?

(2008) Penny Bring et al.   CLINICAL PHARMACOKINETICS