Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells

Advanced pancreatic ductal adenocarcinoma - Complexities of treatment and emerging therapeutic options

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Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration

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Physiology of intracellular potassium channels: A unifying role as mediators of counterion fluxes?

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Pharmacological targeting of ion channels for cancer therapy: In vivo evidences

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Impact of intracellular ion channels on cancer development and progression

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Mitochondrial ROS regulation of proliferating cells

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Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma

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Organellar channels and transporters

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Biophysical Characterization and Expression Analysis of Kv1.3 Potassium Channel in Primary Human Leukemic B Cells

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Early effects of the antineoplastic agent salinomycin on mitochondrial function

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Cancer statistics, 2014

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Effect of immunosuppression on the human mesangial cell cycle

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Potassium channels in cell cycle and cell proliferation

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Mitochondrial Channels: Ion Fluxes and More

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The voltage-dependent K+ channels Kv1.3 and Kv1.5 in human cancer

(2013) Núria Comes et al.   Frontiers in Physiology

Kv1.3 Channels Can Modulate Cell Proliferation During Phenotypic Switch by an Ion-Flux Independent Mechanism

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Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells

(2012) Luigi Leanza et al.   EMBO Molecular Medicine

C5b-9-activated, Kv1.3 channels mediate oligodendrocyte cell cycle activation and dedifferentiation

(2011) Cosmin A. Tegla et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Clofazimine: current status and future prospects

(2011) M. C. Cholo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Functional Blockade of the Voltage-gated Potassium Channel Kv1.3 Mediates Reversion of T Effector to Central Memory Lymphocytes through SMAD3/p21cip1Signaling

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Downregulation of voltage-dependent anion channel-1 expression by RNA interference prevents cancer cell growth in vivo

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Anti-proliferative effect of Kv1.3 blockers in A549 human lung adenocarcinoma in vitro and in vivo

(2010) Soo Hwa Jang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mitochondrial potassium channels and reactive oxygen species

(2010) Dominika Malinska et al.   FEBS LETTERS

The causes of cancer revisited: “Mitochondrial malignancy” and ROS-induced oncogenic transformation – Why mitochondria are targets for cancer therapy

(2010) Stephen J. Ralph et al.   MOLECULAR ASPECTS OF MEDICINE

The functional network of ion channels in T lymphocytes

(2009) Michael D. Cahalan et al.   IMMUNOLOGICAL REVIEWS

Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger

(2009) Stephen J. Ralph et al.   MOLECULAR ASPECTS OF MEDICINE

Targeting Ion Channels in Cancer: A Novel Frontier in Antineoplastic Therapy

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