A TBX5 3′UTR variant increases the risk of congenital heart disease in the Han Chinese population

MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis

(2016) Xin Wang et al.   CARDIOVASCULAR RESEARCH

miRNA-940 reduction contributes to human Tetralogy of Fallot development

(2014) Dandan Liang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MiR-10a and MiR-10b Target the 3′-Untranslated Region of TBX5 to Repress Its Expression

(2014) Feng Wang et al.   PEDIATRIC CARDIOLOGY

Characterization of Circulating MicroRNA Expression in Patients with a Ventricular Septal Defect

(2014) Dong Li et al.   PLoS One

Distinct tissue-specific requirements for the zebrafish tbx5 genes during heart, retina and pectoral fin development

(2014) A. Pi-Roig et al.   Open Biology

MicroRNA-421 Dysregulation is Associated with Tetralogy of Fallot

(2014) Douglas Bittel et al.   Cells

Replication of Relevant SNPs Associated with Cardiovascular Disease Susceptibility Obtained from GWAs in a Case-Control Study in a Canarian Population

(2013) Francisco Rodríguez Esparragón et al.   DISEASE MARKERS

Genetic variants reducing MTR gene expression increase the risk of congenital heart disease in Han Chinese populations

(2013) J.-Y. Zhao et al.   EUROPEAN HEART JOURNAL

In vivo cardiac reprogramming contributes to zebrafish heart regeneration

(2013) Ruilin Zhang et al.   NATURE

Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16

(2013) Heather J Cordell et al.   NATURE GENETICS

A functional variant in the cystathionine β-synthase gene promoter significantly reduces congenital heart disease susceptibility in a Han Chinese population

(2012) Jian-Yuan Zhao et al.   CELL RESEARCH

A New Level of Complexity

(2012) Thomas Boettger et al.   CIRCULATION RESEARCH

Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease

(2012) Scott Smemo et al.   HUMAN MOLECULAR GENETICS

MicroRNA 218 Mediates the Effects of Tbx5a Over-Expression on Zebrafish Heart Development

(2012) Elena Chiavacci et al.   PLoS One

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

(2012) B. C. Bernardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional analysis of the novel sequence variants within TBX5 gene promoter in patients with ventricular septal defects

(2012) Jiping Shan et al.   Translational Research

GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease

(2011) Bradley E Aouizerat et al.   BMC Cardiovascular Disorders

Functional Variant in Methionine Synthase Reductase Intron-1 Significantly Increases the Risk of Congenital Heart Disease in the Han Chinese Population

(2011) Jian-Yuan Zhao et al.   CIRCULATION

Genome-Wide Association Studies of the PR Interval in African Americans

(2011) J. Gustav Smith et al.   PLoS Genetics

Functional analysis of novel TBX5 T-box mutations associated with Holt-Oram syndrome

(2010) C. J. J. Boogerd et al.   CARDIOVASCULAR RESEARCH

Association of polymorphisms in 9p21 region with CAD in North Indian population: replication of SNPs identified through GWAS

(2010) J Kumar et al.   CLINICAL GENETICS

Assessment of variability in GWAS with CRLMM genotyping algorithm on WTCCC coronary artery disease

(2010) L Zhang et al.   PHARMACOGENOMICS JOURNAL

Tbx5-mediated expression of Ca2+/calmodulin-dependent protein kinase II is necessary for zebrafish cardiac and pectoral fin morphogenesis

(2009) Sarah C. Rothschild et al.   DEVELOPMENTAL BIOLOGY

Pdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation

(2009) Troy Camarata et al.   DEVELOPMENTAL BIOLOGY

The Emerging Role of MicroRNAs in Cardiac Remodeling and Heart Failure

(2008) Vijay Divakaran et al.   CIRCULATION RESEARCH

The developmental genetics of congenital heart disease

(2008) Benoit G. Bruneau   NATURE