Article
Family Studies
Shaddy K. Saba, Jessica Godwin, Sunghyun H. Hong, Tiffany Pan, Yujeong Chang, Eleanor Brindle, Todd I. Herrenkohl
Summary: The study compares associations between childhood maltreatment and adult physiological dysregulation using multiple dimension reduction approaches and measures of maltreatment. The significance and magnitude of effects varied with different maltreatment and physiological dysregulation measures. Further review of the methods used to study adult health conditions and their relation to childhood maltreatment is needed.
CHILD ABUSE & NEGLECT
(2023)
Article
Medicine, General & Internal
Yanxia Lu, Xinyi Gwee, Denise Q. L. Chua, Crystal T. Y. Tan, Keng Bee Yap, Anis Larbi, Tze Pin Ng
Summary: The co-occurrence of multi-system physiological dysregulation (PD) and physical frailty independently predict mortality and other health outcomes, with increased predictive accuracy when combined. PD seems to be a valid representation of a biological endo-phenotype of frailty, suggesting that further studies on subclinical measures of frailty could be beneficial.
FRONTIERS IN MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Fatima Touma, Robert A. Hummer
Summary: This study aimed to understand the disparities in physiological dys-regulation among racial/ethnic and immigrant generation groups in the early adult life course. The results showed that child/adolescent immigrants had lower levels of physiological dysregulation compared to third-plus-generation Whites and third-plus-generation same race/ethnic peers. The impact of socioeconomic, social, and behavioral control variables measured at different stages of life was minimal.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Immunology
Erik L. Knight, Yanping Jiang, Jacqueline Rodriguez-Stanley, David M. Almeida, Christopher G. Engeland, Samuele Zilioli
Summary: Exposure to and perceptions of stress are associated with altered systemic inflammation, with diurnal cortisol slopes playing a role in linking self-reported psychological stress to inflammation. The results support an allostatic load model of psychosomatic health, highlighting the importance of cortisol in understanding the relationship between stress exposure, perceived stress, and immune functioning.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Article
Clinical Neurology
Einar Bredeli, Cecilie L. Vestergaard, Borge Sivertsen, Havard Kallestad, Simon Overland, Lee M. Ritterband, Nick Glozier, Stale Pallesen, Jan Scott, Knut Langsrud, Oystein Vedaa
Summary: The study found that IIV was significantly associated with scores on the Insomnia Severity Index, dysfunctional beliefs and attitudes about sleep, fatigue levels, body mass index, and alcohol consumption. However, the association with mental health outcomes was not significant, and IIV was related to a more positively rated sleep quality.
Article
Endocrinology & Metabolism
Kalee De France, Gary W. Evans, Gene H. Brody, Stacey N. Doan
Summary: Childhood poverty is associated with higher levels of internalizing symptoms, but some children show remarkable resilience and exhibit lower levels of psychological distress. However, recent research suggests that coping with adversity can have negative effects on physical health. This study examines whether low levels of internalizing symptoms in childhood poverty are related to elevated chronic physiological stress over time.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Stacey N. Doan, Alicia S. Davis, Molly Lazarus, Akriti Poudel, Phil Tran, Natalie Clark, Thomas E. Fuller-Rowell
Summary: Belonging to an institution is often seen as a protective factor against the negative effects of discrimination and racial climate stress. However, recent research suggests that when individuals experience discrimination from the same institution they identify with, belonging can actually have detrimental effects. This study aimed to investigate the role of institutional belonging in moderating the relationship between racial climate stress and health.
JOURNAL OF RACIAL AND ETHNIC HEALTH DISPARITIES
(2023)
Article
Multidisciplinary Sciences
Fernando A. Campos, Elizabeth A. Archie, Laurence R. Gesquiere, Jenny Tung, Jeanne Altmann, Susan C. Alberts
Summary: The study found that female baboons with higher levels of glucocorticoids face an increased risk of death, and differences in HPA axis activity among individuals provide valuable information about disparities in lifespan.
Article
Public, Environmental & Occupational Health
Dawei Zhu, Xin Ye, Wentao Li, Ruoxi Ding, Ping He
Summary: This study found that there are urban-rural disparities in physiological health in China, with the urban health advantage approach being offset or even reversed by the urban health penalty approach as individuals age.
Article
Public, Environmental & Occupational Health
Jourdyn A. Lawrence, Ichiro Kawachi, Kellee White, Mary T. Bassett, David R. Williams
Summary: This paper examines the associations between different measures of discrimination and allostatic load. The results suggest that everyday discrimination is associated with elevated lipids, while lifetime discrimination is associated with lower sympathetic nervous system, greater cardiovascular risk scores, increased inflammation, metabolic glucose, and metabolic lipids. Appraised burden has nuanced associations with metabolic glucose and parasympathetic nervous system scores.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Biology
Jessica R. Dietch, Alisa Huskey, Ian O. Dadeboe, Danica C. Slavish, Daniel J. Taylor
Summary: The objective of this study was to examine the relationship between sleep characteristics and college degree attainment. The results showed that the strongest predictors of degree attainment were female gender, greater age, higher GPA, and lower intraindividual variability in sleep duration. The study highlights the importance of considering variability in sleep duration, in addition to mean sleep duration, in predicting college retention.
CHRONOBIOLOGY INTERNATIONAL
(2023)
Article
Medicine, General & Internal
Charles C. Lanfear, Rebecca Bucci, David S. Kirk, Robert J. Sampson
Summary: This study examines the differences in exposure to firearm violence by race, sex, and cohort in a longitudinal survey of children in the United States. The findings show significant disparities in exposure to violence based on race and sex, suggesting that societal conditions play a key role. The study highlights the importance of understanding the factors influencing exposure to firearm violence. Evaluation: 8 out of 10.
Review
Behavioral Sciences
Sabine Finlay, Cody Roth, Tiansha Zimsen, Zoltan Sarnyai, Brett McDermott, Tahnee Lee Bridson
Summary: This study systematically reviewed the association between Adverse Childhood Experiences (ACEs) and Allostatic Load (AL), finding that ACEs are associated with elevated AL and poorer health outcomes in adulthood. Furthermore, health risk behaviors, social support, and coping resources moderate or mediate this association.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Endocrinology & Metabolism
Arun S. Karlamangla, David M. Almeida, Margie E. Lachman, Sharon Stein Merkin, Duncan Thomas, Teresa E. Seeman
Summary: This article discusses the importance of including measures of dysregulated system dynamics in the operationalization of allostatic load. It highlights the association between compression of cortisol diurnal dynamic range and dysregulation in other physiological systems, as well as cognitive decline and all-cause mortality. The findings suggest that incorporating measures of system dynamics in the next generation of allostatic load measurement can enhance understanding of the physiological burden of chronic stress and improve prediction of future health consequences.
PSYCHONEUROENDOCRINOLOGY
(2022)
Review
Endocrinology & Metabolism
Francis Osei, Andrea Block, Pia-Maria Wippert
Summary: This systematic review examined the association between the primary mediators of allostatic load and metabolic syndrome. The study found that higher levels of serum cortisol, salivary cortisol, urinary cortisol, hair cortisol, and lower levels of DHEAS were associated with metabolic syndrome.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Psychology, Clinical
Bei Bei, Donna M. Pinnington, Nina Quin, Lin Shen, Michelle Blumfield, Joshua F. Wiley, Sean P. A. Drummond, Louise K. Newman, Rachel Manber
Summary: This study evaluated the feasibility and efficacy of a scalable cognitive behavioural therapy (CBT) sleep intervention tailored for gestational parents during pregnancy and postpartum periods. The results showed that CBT was effective in reducing insomnia severity and sleep disturbance, and improving sleep-related impairment. Participants with elevated insomnia symptoms at baseline benefited more from CBT, but there were no significant effects on symptoms of depression or anxiety.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Developmental
Rebecca Cooper, Maria A. Di Biase, Bei Bei, Nicholas B. Allen, Orli Schwartz, Sarah Whittle, Vanessa Cropley
Summary: The preference for morning or evening rhythms during adolescence can predict both neurodevelopmental and psychological outcomes in adolescents.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Oncology
Judith E. Carroll, Zev M. Nakamura, Brent J. Small, Xingtao Zhou, Harvey J. Cohen, Tim A. Ahles, Jaeil Ahn, Traci N. Bethea, Martine Extermann, Deena Graham, Claudine Isaacs, Heather S. L. Jim, Paul B. Jacobsen, Brenna C. McDonald, Sunita K. Patel, Kelly Rentscher, James Root, Andrew J. Saykin, Danielle B. Tometich, Kathleen Van Dyk, Wanting Zhai, Elizabeth C. Breen, Jeanne S. Mandelblatt
Summary: The study examined the longitudinal relationships between levels of C-reactive protein (CRP) and cognition in older breast cancer survivors and noncancer controls. The results showed that breast cancer survivors had higher levels of CRP, and increased CRP levels predicted lower cognitive function. This suggests that chronic inflammation may play a role in the development of cognitive problems.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Psychology, Clinical
Sumedha Verma, Nina Quin, Laura Astbury, Cornelia Wellecke, Joshua F. Wiley, Margot Davey, Shantha M. W. Rajaratnam, Bei Bei
Summary: This study compared the efficacy of cognitive behavioural therapy (CBT) and light dark therapy (LDT) with treatment-as-usual (TAU) in reducing postpartum insomnia symptoms. The results showed that both CBT and LDT were effective in reducing insomnia symptoms, with sustained improvements at follow-up.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Clinical Neurology
Sean P. A. Drummond, Joshua F. Wiley, Johanna M. Boardman, Eugene Aidman, Elizabeth A. Kensinger, Tony J. Cunningham
Article
Clinical Neurology
Rachel Manber, Carmela Alcantara, Bei Bei, Charles M. Morin, Annemieke A. van Straten
Summary: In this Round Table Discussion, an international panel of experts discussed the use of technology in delivering cognitive behavioral therapy for insomnia (CBT-I) and increasing its reach. The experts shared that the most common method is through video calls, covered by publicly funded health insurance programs like Medicare, especially during the COVID-19 pandemic. There are also fully automated insomnia treatment programs, but they are usually not covered by Medicare or other health insurance programs.
Article
Immunology
Jeffrey D. Galley, Lauren Mashburn-Warren, Lexie C. Blalock, Christian L. Lauber, Judith E. Carroll, Kharah M. Ross, Calvin Hobel, Mary Coussons-Read, Christine Dunkel Schetter, Tamar L. Gur
Summary: Uncovering the mechanisms of fetal programming during pregnancy is crucial for understanding long-term health outcomes in offspring. Maternal factors such as inflammation, stress, anxiety, and depression have been linked to abnormal neurodevelopment and can potentially disrupt the microbiome, which is important for normal brain development. This study examined the association between maternal stress, anxiety, depression, inflammatory cytokines, and the offspring microbiome in the first 13 months of life. The results showed that higher maternal anxiety and stress were associated with reduced microbial diversity and altered abundance of beneficial bacterial species in the offspring. This provides strong evidence for a potential mechanism by which maternal factors can impact offspring health through dysregulation of the microbiota.
BRAIN BEHAVIOR AND IMMUNITY
(2023)
Article
Psychology, Developmental
Eunyeong Jang, Solbi Kang, Bei Bei, Seockhoon Chung, Michael Gradisar, Michal Kahn, Natalie Barnett, Sooyeon Suh
Summary: This study developed an assessment tool called PUMBA-Q to measure parental understanding and misperceptions about baby's sleep. The questionnaire was validated using self-report and objective sleep measures. The results showed the link between parental cognitions and child sleep, highlighting the importance of managing parental cognitions about child sleep when treating pediatric sleep problems.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Endocrinology & Metabolism
Robin Ortiz, Songzhu Zhao, David M. Kline, Guy Brock, Judith E. Carroll, Teresa E. Seeman, Sara R. Jaffee, Jeffrey S. Berger, Sherita H. Golden, Mercedes R. Carnethon, Joshua J. Joseph
Summary: Early life stress (ELS) is associated with increased morbidity and mortality. The relationship between ELS and cortisol levels may explain the connection to poor health outcomes, but previous studies have been limited by the cortisol measures used.
PSYCHONEUROENDOCRINOLOGY
(2023)
Article
Clinical Neurology
Marie-Antoinette Spina, Thomas Andrillon, Nina Quin, Joshua F. Wiley, Shantha M. W. Rajaratnam, Bei Bei
Summary: This study aimed to investigate whether monitoring sleep using wearable devices and providing support for interpretation of sensor-based sleep data improved insomnia symptoms or impacted sleep-wake state discrepancy. The results showed that the intervention group had lower insomnia severity and sleep disturbance compared to the control group. However, there were no significant differences in sleep-wake state discrepancy.
Article
Clinical Neurology
Sumedha Verma, Donna M. Pinnington, Rachel Manber, Bei Bei
Summary: This study investigated the changes in sleep timing and chronotype from late pregnancy to 2 years postpartum, and examined their associations with symptoms of insomnia, daytime sleep-related impairment, and mood. The results showed that sleep timing and chronotype became progressively earlier over the 2 postpartum years, and morningness chronotype may be sleep-protective during the transition from pregnancy to parenthood.
JOURNAL OF SLEEP RESEARCH
(2023)
Review
Clinical Neurology
Meagan E. Crowther, William J. Saunders, Tracey L. Sletten, Sean P. A. Drummond, Bei Bei
Summary: Cognitive behavioural therapy for insomnia (CBT-I) is considered the front-line treatment for insomnia. This review summarizes the literature on tailoring CBT-I to different individuals and identifies gaps in research methodology and treatment development process. It highlights the need to evaluate the benefits of adaptations in CBT-I and involve consumers and stakeholders throughout the process.
JOURNAL OF SLEEP RESEARCH
(2023)
Letter
Oncology
Judith E. E. Carroll, Jeanne S. S. Mandelblatt, Elizabeth C. C. Breen
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Victoria Dax, Maria Ftanou, Ben Tran, Jeremy Lewin, Joshua F. Wiley
Summary: Psychological distress is common in men with testicular cancer, and masculinities may work to explain this. This study found that masculinities are implicated in psychological distress in men with testicular cancer, and psychological flexibility as well as leveraging masculine beliefs, such as optimistic action, may be modifiable targets to reduce distress.