Technical Advances in the Measurement of Residual Disease in Acute Myeloid Leukemia

UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

(2017) Tom Smith et al.   GENOME RESEARCH

Minimal residual disease prior to allogeneic hematopoietic cell transplantation in acute myeloid leukemia: a meta-analysis

(2017) Sarah A. Buckley et al.   HAEMATOLOGICA

Minimal Residual Disease Monitoring of Acute Myeloid Leukemia by Massively Multiplex Digital PCR in Patients with NPM1 Mutations

(2017) Nuria Mencia-Trinchant et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Measurable residual disease testing in acute myeloid leukaemia

(2017) C S Hourigan et al.   LEUKEMIA

Current and Emerging Applications of Droplet Digital PCR in Oncology

(2017) Susana Olmedillas-López et al.   Molecular Diagnosis & Therapy

Minimal residual disease prior to allogeneic hematopoietic cell transplantation in acute myeloid leukemia: a meta-analysis

(2017) Sarah A. Buckley et al.   HAEMATOLOGICA

Comparison of 2 Commercially Available Next-Generation Sequencing Platforms in Oncology

(2017) Nicole M. Kuderer et al.   JAMA Oncology

18 FDG-PET/CT: 21st century approach to leukemic tumors in 124 cases

(2016) Isabel Cunningham et al.   AMERICAN JOURNAL OF HEMATOLOGY

Multigene Measurable Residual Disease Assessment Improves Acute Myeloid Leukemia Relapse Risk Stratification in Autologous Hematopoietic Cell Transplantation

(2016) Matthew P. Mulé et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

(2016) Hartmut Döhner et al.   BLOOD

Usefulness and pitfalls of F-18-FDG PET/CT for diagnosing extramedullary acute leukemia

(2016) Wen-lan Zhou et al.   EUROPEAN JOURNAL OF RADIOLOGY

When the Minimal Becomes Measurable

(2016) Christopher S. Hourigan et al.   JOURNAL OF CLINICAL ONCOLOGY

Extramedullary Disease in Adult Acute Myeloid Leukemia Is Common but Lacks Independent Significance: Analysis of Patients in ECOG-ACRIN Cancer Research Group Trials, 1980-2008

(2016) Chezi Ganzel et al.   JOURNAL OF CLINICAL ONCOLOGY

Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia: Time to Move Toward a Minimal Residual Disease–Based Definition of Complete Remission?

(2016) Daisuke Araki et al.   JOURNAL OF CLINICAL ONCOLOGY

Assessment of Minimal Residual Disease in Standard-Risk AML

(2016) Adam Ivey et al.   NEW ENGLAND JOURNAL OF MEDICINE

A multigene array for measurable residual disease detection in AML patients undergoing SCT

(2015) M Goswami et al.   BONE MARROW TRANSPLANTATION

Droplet digital polymerase chain reaction for DNMT3A and IDH1/2 mutations to improve early detection of acute myeloid leukemia relapse after allogeneic hematopoietic stem cell transplantation

(2015) Chiara Brambati et al.   HAEMATOLOGICA

Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia

(2015) Jeffery M. Klco et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Identification of the NUP98-PHF23 fusion gene in pediatric cytogenetically normal acute myeloid leukemia by whole-transcriptome sequencing

(2015) Marco Togni et al.   Journal of Hematology & Oncology

Quantifying ultra-rare pre-leukemic clones via targeted error-corrected sequencing

(2015) A L Young et al.   LEUKEMIA

Advancing the Minimal Residual Disease Concept in Acute Myeloid Leukemia

(2015) Peter Hokland et al.   SEMINARS IN HEMATOLOGY

Droplet digital polymerase chain reaction for DNMT3A and IDH1/2 mutations to improve early detection of acute myeloid leukemia relapse after allogeneic hematopoietic stem cell transplantation

(2015) Chiara Brambati et al.   HAEMATOLOGICA

Acute myeloid leukemia: 2014 Update on risk-stratification and management

(2015) Elihu H. Estey   AMERICAN JOURNAL OF HEMATOLOGY

Can we say farewell to monitoring minimal residual disease in acute promyelocytic leukaemia?

(2014) David Grimwade et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Prospective Validation of a New Method of Monitoring Minimal Residual Disease in Childhood Acute Myelogenous Leukemia

(2014) D. Steinbach et al.   CLINICAL CANCER RESEARCH

Accurate quantitation of JAK2 V617F allele burden by array-based digital PCR

(2014) E. Kinz et al.   International Journal of Laboratory Hematology

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

(2014) Liran I. Shlush et al.   NATURE

Theoretical and experimental assessment of degenerate primer tagging in ultra-deep applications of next-generation sequencing

(2014) Richard H. Liang et al.   NUCLEIC ACIDS RESEARCH

CBFA2T3-GLIS2 fusion transcript is a novel common feature in pediatric, cytogenetically normal AML, not restricted to FAB M7 subtype

(2013) R. Masetti et al.   BLOOD

A phase 3 study of gemtuzumab ozogamicin during induction and postconsolidation therapy in younger patients with acute myeloid leukemia

(2013) S. H. Petersdorf et al.   BLOOD

Extramedullary disease in patients with acute myeloid leukemia assessed by (18)F-FDG PET

(2013) Anne-Sofie Weindel Ibar Cribe et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Monitoring of residual disease by next-generation deep-sequencing of RUNX1 mutations can identify acute myeloid leukemia patients with resistant disease

(2013) A Kohlmann et al.   LEUKEMIA

Absolute quantification by droplet digital PCR versus analog real-time PCR

(2013) Christopher M Hindson et al.   NATURE METHODS

Minimal residual disease in acute myeloid leukaemia

(2013) Christopher S. Hourigan et al.   Nature Reviews Clinical Oncology

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia

(2013) Francesco Lo-Coco et al.   NEW ENGLAND JOURNAL OF MEDICINE

Minimal residual disease monitoring by quantitative RT-PCR in core binding factor AML allows risk stratification and predicts relapse: results of the United Kingdom MRC AML-15 trial

(2012) J. A. L. Yin et al.   BLOOD

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

(2012) John S. Welch et al.   CELL

Next-generation sequencing for minimal residual disease monitoring in acute myeloid leukemia patients with FLT3-ITD or NPM1 mutations

(2012) Felicitas Thol et al.   GENES CHROMOSOMES & CANCER

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

(2012) Li Ding et al.   NATURE

New Fusion Transcripts Identified in Normal Karyotype Acute Myeloid Leukemia

(2012) Hongxiu Wen et al.   PLoS One

Detection of ultra-rare mutations by next-generation sequencing

(2012) M. W. Schmitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Digital RNA sequencing minimizes sequence-dependent bias and amplification noise with optimized single-molecule barcodes

(2012) K. Shiroguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

(2011) Benjamin J. Hindson et al.   ANALYTICAL CHEMISTRY

18F-FDG-PET/CT for detection of extramedullary acute myeloid leukemia

(2011) F. Stolzel et al.   HAEMATOLOGICA

Impact of Pretransplantation Minimal Residual Disease, As Detected by Multiparametric Flow Cytometry, on Outcome of Myeloablative Hematopoietic Cell Transplantation for Acute Myeloid Leukemia

(2011) Roland B. Walter et al.   JOURNAL OF CLINICAL ONCOLOGY

Somatic coding mutations in human induced pluripotent stem cells

(2011) Athurva Gore et al.   NATURE

Counting absolute numbers of molecules using unique molecular identifiers

(2011) Teemu Kivioja et al.   NATURE METHODS

Genotype and SNP calling from next-generation sequencing data

(2011) Rasmus Nielsen et al.   NATURE REVIEWS GENETICS

Counting individual DNA molecules by the stochastic attachment of diverse labels

(2011) G. K. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID

(2011) C. B. Jabara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection and quantification of rare mutations with massively parallel sequencing

(2011) I. Kinde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries

(2011) Daniel Aird et al.   GENOME BIOLOGY

Early assessment of treatment response in patients with AML using [18F]FLT PET imaging

(2010) Matt Vanderhoek et al.   LEUKEMIA RESEARCH

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

(2010) Ramin Nazarian et al.   NATURE

Real-Time Quantitative Polymerase Chain Reaction Detection of Minimal Residual Disease by StandardizedWT1Assay to Enhance Risk Stratification in Acute Myeloid Leukemia: A European LeukemiaNet Study

(2009) Daniela Cilloni et al.   JOURNAL OF CLINICAL ONCOLOGY

Prospective Minimal Residual Disease Monitoring to Predict Relapse of Acute Promyelocytic Leukemia and to Direct Pre-Emptive Arsenic Trioxide Therapy

(2009) David Grimwade et al.   JOURNAL OF CLINICAL ONCOLOGY

Anthracycline Dose Intensification in Acute Myeloid Leukemia

(2009) Hugo F. Fernandez et al.   NEW ENGLAND JOURNAL OF MEDICINE

First Demonstration of Leukemia Imaging with the Proliferation Marker 18F-Fluorodeoxythymidine

(2008) A. K. Buck et al.   JOURNAL OF NUCLEAR MEDICINE

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

(2008) Timothy J. Ley et al.   NATURE

Substantial biases in ultra-short read data sets from high-throughput DNA sequencing

(2008) J. C. Dohm et al.   NUCLEIC ACIDS RESEARCH

Mathematical Analysis of Copy Number Variation in a DNA Sample Using Digital PCR on a Nanofluidic Device

(2008) Simant Dube et al.   PLoS One