Multi-target chimaeric VLP as a therapeutic vaccine in a model of colorectal cancer

Abstract 2232: Immune-inflammatory markers predict the outcome of metastatic colorectal cancer patients treated with the thymidylate synthase poly-epitope peptide (TSPP) vaccine: results from a multi-arm TSPP/VAC phase Ib program:

(2016) Pierpaolo Correale et al.   CANCER RESEARCH

Abstract 2235: Clinical results of a Phase I/II trial of adjuvant therapeutic vaccination in high risk resected prostate cancer patients using autologous dendritic cells loaded with mRNA from primary prostate cancer tissue, hTERT and survivin

(2016) Anne Merete Aa. Tryggestad et al.   CANCER RESEARCH

Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors

(2016) Mutsunori Murahashi et al.   CLINICAL IMMUNOLOGY

Extended evaluation of a phase 1/2 trial on dosing, safety, immunogenicity, and overall survival after immunizations with an advanced-generation Ad5 [E1-, E2b-]-CEA(6D) vaccine in late-stage colorectal cancer

(2015) Joseph P. Balint et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A loss of antitumor therapeutic activity of CEA DNA vaccines is associated with the lack of tumor cells' antigen presentation to Ag-specific CTLs in a colon cancer model

(2015) Euri Ahn et al.   CANCER LETTERS

MC32 tumor cells acquire Ag-specific CTL resistance through the loss of CEA in a colon cancer model

(2015) Sang-Yeul Lee et al.   Human Vaccines & Immunotherapeutics

Phase I study of alphaviral vector (AVX701) in colorectal cancer patients: comparison of immune responses in stage III and stage IV patients

(2015) Michael A Morse et al.   Journal for ImmunoTherapy of Cancer

Immunologic response to the survivin-derived multi-epitope vaccine EMD640744 in patients with advanced solid tumors

(2014) Volker Lennerz et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Phase II Clinical Trial of Multiple Peptide Vaccination for Advanced Head and Neck Cancer Patients Revealed Induction of Immune Responses and Improved OS

(2014) Y. Yoshitake et al.   CLINICAL CANCER RESEARCH

Mannosylation of Virus-Like Particles Enhances Internalization by Antigen Presenting Cells

(2014) Farah Al-Barwani et al.   PLoS One

Comparative quantitative monitoring of rabbit haemorrhagic disease viruses in rabbit kittens

(2014) Markus Matthaei et al.   Virology Journal

Stage at diagnosis and colorectal cancer survival in six high-income countries: A population-based study of patients diagnosed during 2000–2007

(2013) Camille Maringe et al.   ACTA ONCOLOGICA

Effects of pre-existing anti-carrier immunity and antigenic element multiplicity on efficacy of a modular virus-like particle vaccine

(2013) Yap P. Chuan et al.   BIOTECHNOLOGY AND BIOENGINEERING

A Randomized Phase II Trial of Multiepitope Vaccination with Melanoma Peptides for Cytotoxic T Cells and Helper T Cells for Patients with Metastatic Melanoma (E1602)

(2013) C. L. Slingluff et al.   CLINICAL CANCER RESEARCH

Transpouch prostate biopsy: a word of caution

(2013) R. E. Lovegrove et al.   Colorectal Disease

An Enhanced Heterologous Virus-Like Particle for Human Papillomavirus Type 16 Tumour Immunotherapy

(2013) Khairunadwa Jemon et al.   PLoS One

Atomic Model of Rabbit Hemorrhagic Disease Virus by Cryo-Electron Microscopy and Crystallography

(2013) Xue Wang et al.   PLoS Pathogens

Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma

(2012) Surasak Phuphanich et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Virus-like particles and α-galactosylceramide form a self-adjuvanting composite particle that elicits anti-tumor responses

(2012) Sara J. McKee et al.   JOURNAL OF CONTROLLED RELEASE

Antigen Incorporated In Virus-like Particles Is Delivered to Specific Dendritic Cell Subsets That Induce An Effective Antitumor Immune Response In Vivo

(2012) Kunyu Li et al.   JOURNAL OF IMMUNOTHERAPY

Cross-presentation of epitopes on virus-like particles via the MHC I receptor recycling pathway

(2011) Stephanie J Win et al.   IMMUNOLOGY AND CELL BIOLOGY

High-Resolution Cryo-Electron Microscopy Structures of Murine Norovirus 1 and Rabbit Hemorrhagic Disease Virus Reveal Marked Flexibility in the Receptor Binding Domains

(2010) U. Katpally et al.   JOURNAL OF VIROLOGY

Topoisomerase II alpha as a universal tumor antigen: antitumor immunity in murine tumor models and H-2Kb-restricted T cell epitope

(2009) Jung-Sun Park et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Identification and characterization of survivin-derived H-2Kb-restricted CTL epitopes

(2009) Uta B. Hofmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer

(2009) Eric Van Cutsem et al.   NEW ENGLAND JOURNAL OF MEDICINE

Survivin: Key Regulator of Mitosis and Apoptosis and Novel Target for Cancer Therapeutics

(2008) A. C. Mita et al.   CLINICAL CANCER RESEARCH

Wild-TypeKRASIs Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer

(2008) Rafael G. Amado et al.   JOURNAL OF CLINICAL ONCOLOGY

K-rasMutations and Benefit from Cetuximab in Advanced Colorectal Cancer

(2008) Christos S. Karapetis et al.   NEW ENGLAND JOURNAL OF MEDICINE

DNA topoisomerases: harnessing and constraining energy to govern chromosome topology

(2008) Allyn J. Schoeffler et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Virus-like particles from rabbit hemorrhagic disease virus can induce an anti-tumor response

(2008) Matthew Peacey et al.   VACCINE